DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment gammaTub37C and Tubg1

DIOPT Version :9

Sequence 1:	NP_001260565.1	Gene:	gammaTub37C / 35199	FlyBaseID:	FBgn0010097	Length:	457	Species:	Drosophila melanogaster
Sequence 2:	NP_665721.1	Gene:	Tubg1 / 252921	RGDID:	628606	Length:	451	Species:	Rattus norvegicus

Alignment Length:	447	Identity:	344/447 - (76%)
Similarity:	401/447 - (89%)	Gaps:	1/447 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MPSEIITLQLGQCGNQIGFEFWKRLCLEHGISPDGVLEDFATDGQDRKDVFFYQADDNHYIPRAV 65
            ||.||||||||||||||||||||:||.||||||:|::|:|||:|.||||||||||||.|||||||
  Rat     1 MPREIITLQLGQCGNQIGFEFWKQLCAEHGISPEGIVEEFATEGTDRKDVFFYQADDEHYIPRAV 65

  Fly    66 LIDLEPRVINNIMTSPYSKLYNQENVFLSKHGGGAGNNWASGFSQGEKVQEEVFDILDREADGSD 130
            |:|||||||::|:.|.|:||||.||::||:||||||||||||||||||:.|::|||:||||||||
  Rat    66 LLDLEPRVIHSILNSSYAKLYNPENIYLSEHGGGAGNNWASGFSQGEKIHEDIFDIIDREADGSD 130

  Fly   131 SLEGFVLCHSIAGGTGSGMGSYVLERLSERFPKKLIQTYSVFPNQDEISDVVVQPYNSILTLKRL 195
            ||||||||||||||||||:|||:||||::|:||||:|||||||||||:||||||||||:||||||
  Rat   131 SLEGFVLCHSIAGGTGSGLGSYLLERLNDRYPKKLVQTYSVFPNQDEMSDVVVQPYNSLLTLKRL 195

  Fly   196 TKCADSVVVLDNTALNRIATERLHIQTPTFTQINNLVSTIMSLSTTTLRYPSYMNNNLIGLTASL 260
            |:.||.||||||||||.|||:|||||.|:|:|||.|||||||.||||||||.||||:||||.|||
  Rat   196 TQNADCVVVLDNTALNLIATDRLHIQNPSFSQINQLVSTIMSASTTTLRYPGYMNNDLIGLIASL 260

  Fly   261 IPTPQLHFLMTGYTPLMSDCETKTSVRKTTVLDVMRRLLQPKNMMVSALTDKQSRQCFVSILNII 325
            ||||:|||||||||||.:| ::..|||||||||||||||||||:|||...|:|:..|:::|||||
  Rat   261 IPTPRLHFLMTGYTPLTTD-QSVASVRKTTVLDVMRRLLQPKNVMVSTGRDRQTNHCYIAILNII 324

  Fly   326 QGEVDPSQVHKSLQRIRERKLANFIPWGPASIQVALPRSSPYVQSAHKVSGLMMANHTGISSLFK 390
            ||||||:|||||||||||||||||||||||||||||.|.|||:.|||:||||||||||.|||||:
  Rat   325 QGEVDPTQVHKSLQRIRERKLANFIPWGPASIQVALSRKSPYLPSAHRVSGLMMANHTSISSLFE 389

  Fly   391 RALAQYDKLRKRNAFLDNFRRESMFQDDLTELDIARDTVDCLVQEYEAATQIDYPQW 447
            |...|:||||||.||::.||:|.:|:|:..|:|.:|:.|..|:.||.|||:.||..|
  Rat   390 RTCRQFDKLRKREAFMEQFRKEDIFKDNFDEMDTSREIVQQLIDEYHAATRPDYISW 446

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
gammaTub37C	NP_001260565.1	PLN00222	1..447	CDD:215108	343/445 (77%)
gammaTub37C	NP_001260565.1	gamma_tubulin	4..436	CDD:276957	334/431 (77%)
Tubg1	NP_665721.1	gamma_tubulin	3..435	CDD:276957	334/432 (77%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	374	1.000	Domainoid score	I844
eggNOG	1	0.900	-	-		E1_COG5023
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H833
Inparanoid	1	1.050	735	1.000	Inparanoid score	I572
OMA	1	1.010	-	-		QHG53966
OrthoDB	1	1.010	-	-		D267298at33208
OrthoFinder	1	1.000	-	-		FOG0002428
OrthoInspector	1	1.000	-	-		mtm9090
orthoMCL	1	0.900	-	-		OOG6_101897
Panther	1	1.100	-	-	O	PTHR11588
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1612
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	15	14.840