Protein Alignment gammaTub37C and TUBB

DIOPT Version :10

• Sequence 1: NP_476922.1
• Gene: gammaTub37C / 35199
• FlyBaseID: FBgn0010097
• Length: 457
• Species: Drosophila melanogaster
• Sequence 2: NP_001280141.1
• Gene: TUBB / 203068
• HGNCID: 20778
• Length: 464
• Species: Homo sapiens
• Alignment Length: 428
• Identity: 142/428 - (33%)
• Similarity: 242/428 - (56%)
• Gaps: 33/428 - (7%)

  Fly    20 EFWKRLCLEHGISPDGVLEDFATDGQDRKDVFFYQADDNHYIPRAVLIDLEPRVINNIMTSPYSK 84
            :||:.:..||||.|.|.....:....||..|::.:|....|:|||:|:||||..::::.:.|:.:
Human    39 KFWEVISDEHGIDPTGTYHGDSDLQLDRISVYYNEATGGKYVPRAILVDLEPGTMDSVRSGPFGQ 103

  Fly    85 LYNQENVFLSKHGGGAGNNWASG-FSQGEKVQEEVFDILDREADGSDSLEGFVLCHSIAGGTGSG 148
            ::..:|....:  .|||||||.| :::|.::.:.|.|::.:||:..|.|:||.|.||:.||||||
Human   104 IFRPDNFVFGQ--SGAGNNWAKGHYTEGAELVDSVLDVVRKEAESCDCLQGFQLTHSLGGGTGSG 166

  Fly   149 MGSYVLERLSERFPKKLIQTYSVFPNQDEISDVVVQPYNSILTLKRLTKCADSVVVLDNTALNRI 213
            ||:.::.::.|.:|.:::.|:||.|: .::||.||:|||:.|::.:|.:..|....:||.||..|
Human   167 MGTLLISKIREEYPDRIMNTFSVVPS-PKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDI 230

  Fly   214 ATERLHIQTPTFTQINNLVSTIMSLSTTTLRYPSYMNNNLIGLTASLIPTPQLHFLMTGYTPLMS 278
            ....|.:.|||:..:|:|||..||..||.||:|..:|.:|..|..:::|.|:|||.|.|:.||.|
Human   231 CFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTS 295

  Fly   279 DCETKTSVRKTTVLDVMRRLLQPKNMMVSALTDKQSRQCFVSILNIIQGEVDPSQVHKSLQRIRE 343
              ......|..||.::.:::...|||| :|...:..|  ::::..:.:|.:...:|.:.:..::.
Human   296 --RGSQQYRALTVPELTQQVFDAKNMM-AACDPRHGR--YLTVAAVFRGRMSMKEVDEQMLNVQN 355

  Fly   344 RKLANFIPWGPASIQVAL----PRSSPYVQSAHKVSGLMMA-----NHTGISSLFKRALAQYDKL 399
            :..:.|:.|.|.:::.|:    ||            ||.||     |.|.|..||||...|:..:
Human   356 KNSSYFVEWIPNNVKTAVCDIPPR------------GLKMAVTFIGNSTAIQELFKRISEQFTAM 408

  Fly   400 RKRNAFLDNFRRESMFQDDLTELDIARDTVDCLVQEYE 437
            .:|.|||..:..|.|.:.:.||   |...::.||.||:
Human   409 FRRKAFLHWYTGEGMDEMEFTE---AESNMNDLVSEYQ 443

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
gammaTub37C	NP_476922.1	gamma_tubulin	4..436	CDD:276957	140/425 (33%)
TUBB	NP_001280141.1	PLN00220	39..449	CDD:215107	142/428 (33%)