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Protein Alignment gammaTub37C and TUBA3D

DIOPT Version :10

Sequence 1:	NP_476922.1	Gene:	gammaTub37C / 35199	FlyBaseID:	FBgn0010097	Length:	457	Species:	Drosophila melanogaster
Sequence 2:	NP_525125.2	Gene:	TUBA3D / 113457	HGNCID:	24071	Length:	450	Species:	Homo sapiens

Alignment Length:	442	Identity:	137/442 - (30%)
Similarity:	239/442 - (54%)	Gaps:	19/442 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 EIITLQLGQCGNQIGFEFWKRLCLEHGISPDGVLEDFAT--DGQDRKDVFFYQADDNHYIPRAVL 66
            |.|::.:||.|.|||...|:..||||||.|||.:....|  .|.|..:.||.:.....::||||.
Human     3 ECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSETGAGKHVPRAVF 67

  Fly    67 IDLEPRVINNIMTSPYSKLYNQENVFLSKHGGGAGNNWASG-FSQGEKVQEEVFDILDREADGSD 130
            :||||.|::.:.|..|.:|::.|.:...|.  .|.||:|.| ::.|:::.:.|.|.:.:.||...
Human    68 VDLEPTVVDEVRTGTYRQLFHPEQLITGKE--DAANNYARGHYTIGKEIVDLVLDRIRKLADLCT 130

  Fly   131 SLEGFVLCHSIAGGTGSGMGSYVLERLSERFPKKLIQTYSVFPNQDEISDVVVQPYNSILTLKRL 195
            .|:||::.||..||||||..|.::||||..:.||....::::| ..::|..||:|||||||....
Human   131 GLQGFLIFHSFGGGTGSGFASLLMERLSVDYGKKSKLEFAIYP-APQVSTAVVEPYNSILTTHTT 194

  Fly   196 TKCADSVVVLDNTALNRIATERLHIQTPTFTQINNLVSTIMSLSTTTLRYPSYMNNNLIGLTASL 260
            .:.:|...::||.|:..|....|.|:.||:|.:|.|:..|:|..|.:||:...:|.:|.....:|
Human   195 LEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLIGQIVSSITASLRFDGALNVDLTEFQTNL 259

  Fly   261 IPTPQLHFLMTGYTPLMSDCETKTSVRKTTVLDVMRRLLQPKNMMVSALTDKQSRQCFVSILNII 325
            :|.|::||.:..|.|::|  ..|....:.:|.::.....:|.|.||..  |.:..: :::...:.
Human   260 VPYPRIHFPLATYAPVIS--AEKAYHEQLSVAEITNACFEPANQMVKC--DPRHGK-YMACCMLY 319

  Fly   326 QGEVDPSQVHKSLQRIRERKLANFIPWGPASIQVALPRSSPYVQSAHKVSGL-----MMANHTGI 385
            :|:|.|..|:.::..|:.::...|:.|.|...:|.:....|.|.....::.:     |::|.|.|
Human   320 RGDVVPKDVNAAIATIKTKRTIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAI 384

  Fly   386 SSLFKRALAQYDKLRKRNAFLDNFRRESMFQDDLTELDIARDTVDCLVQEYE 437
            :..:.|...::|.:..:.||:..:..|.|.:.:.:|   ||:.:..|.::||
Human   385 AEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSE---AREDLAALEKDYE 433

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 592.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.