Protein Alignment gammaTub37C and TUBA3E

DIOPT Version :9

• Sequence 1: NP_001260565.1
• Gene: gammaTub37C / 35199
• FlyBaseID: FBgn0010097
• Length: 457
• Species: Drosophila melanogaster
• Sequence 2: NP_997195.2
• Gene: TUBA3E / 112714
• HGNCID: 20765
• Length: 450
• Species: Homo sapiens
• Alignment Length: 461
• Identity: 136/461 - (29%)
• Similarity: 240/461 - (52%)
• Gaps: 40/461 - (8%)

  Fly     4 EIITLQLGQCGNQIGFEFWKRLCLEHGISPDGVLEDFAT--DGQDRKDVFFYQADDNHYIPRAVL 66
            |.|::.:||.|.|||...|:..||||||.|||.:....|  .|.|..:.||.:.....::||||.
Human     3 ECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSETGAGKHVPRAVF 67

  Fly    67 IDLEPRVINNIMTSPYSKLYNQENVFLSKHGGGAGNNWASG-FSQGEKVQEEVFDILDREADGSD 130
            :||||.|::.:.|..|.:|::.|.:...|.  .|.:|:|.| ::.|:::.:.|.|.:.:.||...
Human    68 VDLEPTVVDEVRTGTYRQLFHPEQLITGKE--DAASNYARGHYTIGKEIVDLVLDRIRKLADLCT 130

  Fly   131 SLEGFVLCHSIAGGTGSGMGSYVLERLSERFPKKLIQTYSVFPNQDEISDVVVQPYNSILTLKRL 195
            .|:||::.||..||||||..|.::||||..:.||....::::| ..::|..||:|||||||....
Human   131 GLQGFLIFHSFGGGTGSGFASLLMERLSVDYSKKSKLEFAIYP-APQVSTAVVEPYNSILTTHTT 194

  Fly   196 TKCADSVVVLDNTALNRIATERLHIQTPTFTQINNLVSTIMSLSTTTLRYPSYMNNNLIGLTASL 260
            .:.:|...::||.|:..|....|.|:.||:|.:|.|:..|:|..|.:||:...:|.:|.....:|
Human   195 LEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLIGQIVSSITASLRFDGALNVDLTEFQTNL 259

  Fly   261 IPTPQLHFLMTGYTPLMSDCETKTSVRKTTVLDVMRRLLQPKNMMVSALTDKQSRQC------FV 319
            :|.|::||.:..|.|::|  ..|....:.:|.::.....:|.|.||         :|      ::
Human   260 VPYPRIHFPLATYAPVIS--AEKAYHEQLSVAEITNACFEPANQMV---------KCDPRHGKYM 313

  Fly   320 SILNIIQGEVDPSQVHKSLQRIRERKLANFIPWGPASIQVALPRSSPYVQSAHKVSGL-----MM 379
            :...:.:|:|.|..|:.::..|:.::...|:.|.|...:|.:....|.|.....::.:     |:
Human   314 ACCMLYRGDVVPKDVNAAIATIKTKRTIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCML 378

  Fly   380 ANHTGISSLFKRALAQYDKLRKRNAFLDNFRRESMFQDDLTEL------------DIARDTVDCL 432
            :|.|.|:..:.|.:.::|.:..:.||:..:..|.|.:.:.:|.            ::..|:|:..
Human   379 SNTTAIAEAWARLVHKFDLMYAKWAFVHWYVGEGMEEGEFSEAREDLAALEKDCEEVGVDSVEAE 443

  Fly   433 VQEYEA 438
            .:|.||
Human   444 AEEGEA 449

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
gammaTub37C	NP_001260565.1	PLN00222	1..447	CDD:215108	136/461 (30%)
		gamma_tubulin	4..436	CDD:276957	133/457 (29%)
TUBA3E	NP_997195.2	PTZ00335	1..440	CDD:185562	132/450 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5023
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810