DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17568 and AZF1

DIOPT Version :9

Sequence 1:	NP_609951.2	Gene:	CG17568 / 35198	FlyBaseID:	FBgn0032763	Length:	513	Species:	Drosophila melanogaster
Sequence 2:	NP_014756.3	Gene:	AZF1 / 854280	SGDID:	S000005639	Length:	914	Species:	Saccharomyces cerevisiae

Alignment Length:	391	Identity:	90/391 - (23%)
Similarity:	153/391 - (39%)	Gaps:	82/391 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   151 SQEMEISKRTTTTHLIQTKKNVEMEIPKQEFIDLGPILLEKNTSQLDMEDVLDELPQEELSQPRL 215
            :.:..|:..|:|            .||.||...|.......| |:.|::::...| ::.|:..
Yeast   383 NNDNSINSATST------------NIPNQEDHSLASTDTTSN-SRKDLKEIEQRL-RKHLNDE-- 431

  Fly   216 DSTTSPASMENDVKSEMLDSCEGDDDFLPVDGQLMDLV-------AVATTPNTLESTAEEKAKRG 273
            |:.:|..|...| |:::::..||.:..:...|...:::       :.....|.:..|....:|..
Yeast   432 DNYSSAISRPLD-KNDVIEGSEGLNKHIDESGMQPNIIKKRKKDDSTVYVKNEMPRTDPPMSKDN 495

  Fly   274 RMDCEKCGKVYRNRASYE------KHLERECRRIERRVKVD---------------KTTTTCD-- 315
            ....|  |....|.:..|      ..:..:...:....|||               |..||.|
Yeast   496 STSAE--GAAMANFSGKEPPIPDISSVSDDATNLIGATKVDQLMLIIQARKKGFTEKVNTTQDGD 558

  Fly   316 -ICNKTLSSATALKLHKEGIHQNVKPYICDSCGKQLKTITALNEHKLVHTESRPFECTVCKAGFK 379
             :.|:|:.   .|....|.:....||       |..:...|:.:|          ||..|...|.
Yeast   559 LLFNQTMD---ILPPKSELVGGVEKP-------KGTQNTRAVKKH----------ECPYCHRLFS 603

  Fly   380 NRARLKAHYQIHA--EPSFVCNICGKKLQTRRTWNMHKVVHTEERRLKCDVCGALFKRSKTLKTH 442
            ....|:.|.:.|.  :| |||:.|||:.........|:.:||.|:...||:|...|.|...|..|
Yeast   604 QATHLEVHVRSHIGYKP-FVCDYCGKRFTQGGNLRTHERLHTGEKPYSCDICDKKFSRKGNLAAH 667

  Fly   443 LLSHTGLRPYVCNY--CGKSFACNANCRSHKLKKHPQEVQQEDGARL----PSRLNVPTLDELRV 501
            |::|..|:|:||..  |.|:|....|.::|:.:.| :|......|:|    ||. |:| |:|.::
Yeast   668 LVTHQKLKPFVCKLENCNKTFTQLGNMKAHQNRFH-KETLNALTAKLAEMNPSE-NIP-LEERQL 729

  Fly   502 M 502
            :
Yeast   730 L 730

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17568	NP_609951.2	zf-AD	10..87	CDD:214871
		COG5048	<313..471	CDD:227381	46/164 (28%)
		C2H2 Zn finger	314..335	CDD:275368	5/23 (22%)
		C2H2 Zn finger	343..363	CDD:275368	3/19 (16%)
		C2H2 Zn finger	371..391	CDD:275368	5/19 (26%)
		C2H2 Zn finger	398..418	CDD:275368	5/19 (26%)
		C2H2 Zn finger	426..446	CDD:275368	8/19 (42%)
		zf-H2C2_2	439..463	CDD:290200	11/25 (44%)
		C2H2 Zn finger	454..475	CDD:275368	6/22 (27%)
AZF1	NP_014756.3	COG5048	342..768	CDD:227381	90/391 (23%)
		C2H2 Zn finger	595..615	CDD:275368	5/19 (26%)
		C2H2 Zn finger	623..643	CDD:275368	5/19 (26%)
		C2H2 Zn finger	651..671	CDD:275368	8/19 (42%)
		C2H2 Zn finger	679..702	CDD:275368	6/22 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24390
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100