DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17568 and STP4

DIOPT Version :9

Sequence 1:	NP_609951.2	Gene:	CG17568 / 35198	FlyBaseID:	FBgn0032763	Length:	513	Species:	Drosophila melanogaster
Sequence 2:	NP_010235.1	Gene:	STP4 / 851512	SGDID:	S000002206	Length:	490	Species:	Saccharomyces cerevisiae

Alignment Length:	431	Identity:	80/431 - (18%)
Similarity:	130/431 - (30%)	Gaps:	147/431 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly   141 LKDFPLAETSSQEMEISKRTTTTHLIQTKKNVEMEIPKQEFIDLGPILLEKNTSQLDMEDVLDEL 205
            |...||:..||..:.:...::.|:||        .:.::||......|....||.:. ..|||.
Yeast   117 LSPTPLSSNSSSHVILPPISSFTNLI--------TVAEREFNGRSNSLHANFTSPVP-RTVLDH- 171

  Fly   206 PQEEL----------------SQPRLDSTTSPASMENDVKSEMLDSCEGDDDFLPVDG------- 247
            .:.||                |.|....:..|.:::|..:|:.:.|       |||.|
Yeast   172 HRHELTFCNPNNTTGFKTITPSPPTQHQSILPTAVDNVPRSKSVSS-------LPVSGFPPLIVK 229

  Fly   248 -----QLMDLVAVATTPNTLESTAEEKAKRGRMDCEKCGKVYRNRASYEKHLERECRRIERRVKV 307
                 ||....:.:..|:.......|...|.....:...|:.:.|...|
Yeast   230 QQQQQQLNSSSSASALPSIHSPLTNEHTSRYSSSLKDSAKITKQRKKKE---------------- 278

  Fly   308 DKTTTTCDICNKTLSSATALKLHKEGIHQNVKPYICDSCGKQLKTITALNEHKLVH--TESRPFE 370
                  |.||:...::                                |:.||..|  .|.||.:
Yeast   279 ------CPICHNFYAN--------------------------------LSTHKSTHLTPEDRPHK 305

  Fly   371 CTVCKAGFKNRARLKAHYQIHAEPSFV-------CNICGKKLQ--TRRT---------------- 410
            |.:|:.||.....|..|.:.|.:..|:       .|..|...|  |.||
Yeast   306 CPICQRGFARNNDLIRHKKRHWKDEFMQIYARESDNNSGADDQDDTARTSANNDSDDSNDKLAAS 370

  Fly   411 ----------WNMHKVVHTEERRLKCDVCGALFKRSKTLKTHLLSHTGLRPYVCNYCGKSFACNA 465
                      .|..|.::..:...||.....|......:..|........|..|:..|....|:
Yeast   371 SSSEETKLLKKNQLKSLYKIKGAFKCPYNSTLINLDMEVYPHKSRSLYFEPINCHQTGVFSRCD- 434

  Fly   466 NCRSHKLK----KHPQEVQQEDGARLPSR-----LNVPTLD 497
            ..::| ||    ::|.:.::||...:|.:     |..|.:|
Yeast   435 TFKNH-LKALHFEYPPKTKKEDRGVVPGKCKHCGLQFPNVD 474

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17568	NP_609951.2	zf-AD	10..87	CDD:214871
		COG5048	<313..471	CDD:227381	34/194 (18%)
		C2H2 Zn finger	314..335	CDD:275368	3/20 (15%)
		C2H2 Zn finger	343..363	CDD:275368	3/19 (16%)
		C2H2 Zn finger	371..391	CDD:275368	6/19 (32%)
		C2H2 Zn finger	398..418	CDD:275368	8/47 (17%)
		C2H2 Zn finger	426..446	CDD:275368	3/19 (16%)
		zf-H2C2_2	439..463	CDD:290200	4/23 (17%)
		C2H2 Zn finger	454..475	CDD:275368	6/24 (25%)
STP4	NP_010235.1	COG5048	14..442	CDD:227381	72/397 (18%)
		C2H2 Zn finger	279..296	CDD:275368	6/48 (13%)
		C2H2 Zn finger	306..326	CDD:275368	6/19 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24390
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100