DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG17568 and ZNF667

DIOPT Version :9

Sequence 1:NP_609951.2 Gene:CG17568 / 35198 FlyBaseID:FBgn0032763 Length:513 Species:Drosophila melanogaster
Sequence 2:NP_001308285.1 Gene:ZNF667 / 63934 HGNCID:28854 Length:610 Species:Homo sapiens


Alignment Length:269 Identity:79/269 - (29%)
Similarity:111/269 - (41%) Gaps:59/269 - (21%)


- Green bases have known domain annotations that are detailed below.


  Fly   265 TAEEKAKRGRMDCEKCGKVYRNRASYEKHL--------------ERECRRIERRVKVDKTTT--- 312
            |:|:..|     |:||.|.:|..::...||              |:.|.|....::..|..|   
Human   353 TSEKPYK-----CDKCDKFFRRLSTLILHLRIHNGEKLYRCNKCEKVCNRHSSLIQHQKVHTKKK 412

  Fly   313 ---TCDICNKTLSSATALKLHK---------------------------EGIHQNVKPYICDSCG 347
               .|..|.|..|....||:|:                           :.||...|||.|:.||
Human   413 KLFECKECGKMFSGTANLKIHQNIHSEEKPFKCNKCSKVFGRQSFLIEHQRIHTGEKPYQCEECG 477

  Fly   348 KQLKTITALNEHKLVHTESRPFECTVCKAGFKNRARLKAHYQIH-AEPSFVCNICGKKLQTRRTW 411
            |......:|..||.:|||.||:||..|...|...|.|..|.:|| .|..:.|..|||....|.:.
Human   478 KAFSHRISLTRHKRIHTEDRPYECDQCGKAFSQSAHLAQHERIHTGEKPYTCKTCGKAFSQRTSL 542

  Fly   412 NMHKVVHTEERRLKCDVCGALFKRSKTLKTHLLSHTGLRPYVCNYCGKSFACNANCRSHKLKKHP 476
            .:|:..||.|:..:|:.||..|.....|..|..||:..:||.|:.|||:::     ||..|.:| 
Human   543 ILHERSHTGEKPYECNECGKAFSSGSDLIRHQRSHSSEKPYECSKCGKAYS-----RSSSLIRH- 601

  Fly   477 QEVQQEDGA 485
            |....|:.|
Human   602 QNTHSEEKA 610

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG17568NP_609951.2 zf-AD 10..87 CDD:214871
COG5048 <313..471 CDD:227381 59/185 (32%)
C2H2 Zn finger 314..335 CDD:275368 7/47 (15%)
C2H2 Zn finger 343..363 CDD:275368 7/19 (37%)
C2H2 Zn finger 371..391 CDD:275368 6/19 (32%)
C2H2 Zn finger 398..418 CDD:275368 6/19 (32%)
C2H2 Zn finger 426..446 CDD:275368 6/19 (32%)
zf-H2C2_2 439..463 CDD:290200 10/23 (43%)
C2H2 Zn finger 454..475 CDD:275368 7/20 (35%)
ZNF667NP_001308285.1 KRAB 15..74 CDD:214630
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 119..139
COG5048 141..601 CDD:227381 75/257 (29%)
C2H2 Zn finger 146..166 CDD:275368
C2H2 Zn finger 174..194 CDD:275368
C2H2 Zn finger 202..222 CDD:275368
C2H2 Zn finger 255..275 CDD:275368
C2H2 Zn finger 284..303 CDD:275368
C2H2 Zn finger 332..352 CDD:275368
C2H2 Zn finger 360..380 CDD:275368 7/19 (37%)
C2H2 Zn finger 388..408 CDD:275368 4/19 (21%)
C2H2 Zn finger 417..437 CDD:275368 7/19 (37%)
C2H2 Zn finger 445..465 CDD:275368 0/19 (0%)
C2H2 Zn finger 473..493 CDD:275368 7/19 (37%)
C2H2 Zn finger 501..521 CDD:275368 6/19 (32%)
C2H2 Zn finger 529..549 CDD:275368 6/19 (32%)
C2H2 Zn finger 557..577 CDD:275368 6/19 (32%)
C2H2 Zn finger 585..605 CDD:275368 9/25 (36%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.910

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