DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17568 and CG4854

DIOPT Version :9

Sequence 1:	NP_609951.2	Gene:	CG17568 / 35198	FlyBaseID:	FBgn0032763	Length:	513	Species:	Drosophila melanogaster
Sequence 2:	NP_650860.1	Gene:	CG4854 / 42391	FlyBaseID:	FBgn0038766	Length:	319	Species:	Drosophila melanogaster

Alignment Length:	295	Identity:	79/295 - (26%)
Similarity:	123/295 - (41%)	Gaps:	64/295 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   188 LLEKNTSQLDMEDVLDELPQEELSQPRLDSTTSPASMENDVKSEMLDS----CEGDDDFLPVDGQ 248
            |.|:...::::|.|.||...::.::.|..|.......:::::.|.|||    .|..:|......:
  Fly    78 LKEQKLQEINIEIVHDEQETKKKTESRDLSKNEATGSDSELEYEYLDSYDVTLESSEDVACSADE 142

  Fly   249 LMDLVAVATTPNTLESTAEEKAKRGRMDCEKCGKVYRNRASYEKHLERECRRIERRVKVDKTTTT 313
            |:.:....:.|.  ||......|....:.|..|:.    ||:                      |
  Fly   143 LVSIEPAISAPE--ESVYSLSPKPVTFEDEDSGQA----ASF----------------------T 179

  Fly   314 CDICNKTLSSATALKLHKEGIHQNVKPYICDSCGKQLKTITALNEHKLVHTESRPFECTVCKAGF 378
            |:|||...|....|..|.: :|...||:.|:.|.|:.:....|..|...||.:||::|..|.:.|
  Fly   180 CNICNNVYSERVKLTNHMK-VHSAKKPHECEICHKRFRQTPQLARHMNTHTGNRPYKCDYCDSRF 243

  Fly   379 KNRARLKAHYQIHAEPSFVCNICGKKLQTRRTWNMHKVVHTEERRLKCDVCGALFKRSKTLKTHL 443
                         |:||              |...|:.:||.||..||:.|...|..|..|:.||
  Fly   244 -------------ADPS--------------TRIKHQRIHTNERPYKCEFCSRSFGYSNVLRVHL 281

  Fly   444 LSHTGLRPYVCNYCGKSFA----CNANCRSHKLKK 474
            .:|||.||:.|.||.|||:    .|::.:|||..|
  Fly   282 KTHTGERPFSCQYCQKSFSQLHHKNSHEKSHKRTK 316

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17568	NP_609951.2	zf-AD	10..87	CDD:214871
		COG5048	<313..471	CDD:227381	53/161 (33%)
		C2H2 Zn finger	314..335	CDD:275368	7/20 (35%)
		C2H2 Zn finger	343..363	CDD:275368	5/19 (26%)
		C2H2 Zn finger	371..391	CDD:275368	3/19 (16%)
		C2H2 Zn finger	398..418	CDD:275368	2/19 (11%)
		C2H2 Zn finger	426..446	CDD:275368	7/19 (37%)
		zf-H2C2_2	439..463	CDD:290200	14/27 (52%)
		C2H2 Zn finger	454..475	CDD:275368	11/25 (44%)
CG4854	NP_650860.1	zf-AD	12..>57	CDD:285071
		C2H2 Zn finger	180..200	CDD:275368	7/20 (35%)
		zf-H2C2_2	193..217	CDD:290200	8/24 (33%)
		COG5048	201..>258	CDD:227381	20/83 (24%)
		C2H2 Zn finger	208..228	CDD:275368	5/19 (26%)
		zf-H2C2_2	221..244	CDD:290200	9/35 (26%)
		C2H2 Zn finger	236..256	CDD:275368	8/46 (17%)
		zf-H2C2_2	251..273	CDD:290200	9/21 (43%)
		C2H2 Zn finger	264..284	CDD:275368	7/19 (37%)
		zf-H2C2_2	277..301	CDD:290200	14/23 (61%)
		C2H2 Zn finger	292..312	CDD:275368	7/19 (37%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	84	1.000	Inparanoid score	I1804
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.050