DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17568 and CG4424

DIOPT Version :9

Sequence 1:	NP_609951.2	Gene:	CG17568 / 35198	FlyBaseID:	FBgn0032763	Length:	513	Species:	Drosophila melanogaster
Sequence 2:	NP_650859.3	Gene:	CG4424 / 42390	FlyBaseID:	FBgn0038765	Length:	345	Species:	Drosophila melanogaster

Alignment Length:	367	Identity:	84/367 - (22%)
Similarity:	130/367 - (35%)	Gaps:	120/367 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly   133 VYQKPAELLKDFPLAETSSQ----EMEISKRTTTTHLIQTKKNVEMEIPKQEFIDLGPILLEKNT 193
            :.|:..|.|:::.:.:...|    |:....|.:|...|:|:   ::|.|:.|.::.|
  Fly    81 ICQRSNEFLREYVIKDAVEQGVVKEVVQQTRPSTPPPIETE---QLEPPEDEVLEEG-------- 134

  Fly   194 SQLDMEDVLDELPQEELSQPRLDSTTSPASMEND--VKSEMLDSCEGDDDFLPVDGQLMDLVAVA 256
             ....||.::|.|.            .||..|..  :..|||.:     .:.|          .|
  Fly   135 -VWSTEDPIEETPH------------GPAEKERPTVLTVEMLPA-----PYPP----------PA 171

  Fly   257 TTPNTLESTAEEKAKRGRMD-CEKCGKVYRNRASYEKHLERECRRIERRVKVDKTTTTCDICNKT 320
            :||    ..|...|.:|::. |..||..|..:::.:.|:.|
  Fly   172 STP----PPAPAGAVKGKLHVCAICGNGYPRKSTLDTHMRR------------------------ 208

  Fly   321 LSSATALKLHKEGIHQNVKPYICDSCGKQLKTITALNEHKLVHTESRPFECTVCKAGFKNRARLK 385
                          |.:.:||.|:.|.|.......|..|...||.::|:.|..|:..|.:|..|.
  Fly   209 --------------HNDERPYECEICHKSFHVNYQLKRHIRQHTGAKPYTCQYCQRNFADRTSLV 259

  Fly   386 AHYQIHAEPSFVCNICGKKLQTRRTWNMHKVVHTEERRLKCDVCGALFKRSKTLKTHLLSHTGLR 450
            .|                    .||       |..||...|..||..|..:..||.|..:|||.:
  Fly   260 KH--------------------ERT-------HRNERPYACKTCGKKFTYASVLKMHYKTHTGEK 297

  Fly   451 PYVCNYCGKSFACNANCRSHKLKKHPQEVQQEDGARLPSRLN 492
            |::|..|.||||     |.|.|..|.|..|..:..||.:.|:
  Fly   298 PHICQLCNKSFA-----RIHNLVAHLQTQQHINDPRLTAYLS 334

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17568	NP_609951.2	zf-AD	10..87	CDD:214871
		COG5048	<313..471	CDD:227381	40/157 (25%)
		C2H2 Zn finger	314..335	CDD:275368	0/20 (0%)
		C2H2 Zn finger	343..363	CDD:275368	5/19 (26%)
		C2H2 Zn finger	371..391	CDD:275368	6/19 (32%)
		C2H2 Zn finger	398..418	CDD:275368	2/19 (11%)
		C2H2 Zn finger	426..446	CDD:275368	7/19 (37%)
		zf-H2C2_2	439..463	CDD:290200	12/23 (52%)
		C2H2 Zn finger	454..475	CDD:275368	9/20 (45%)
CG4424	NP_650859.3	zf-AD	10..92	CDD:285071	3/10 (30%)
		C2H2 Zn finger	189..209	CDD:275368	6/57 (11%)
		DUF45	<204..281	CDD:302795	27/141 (19%)
		COG5048	210..>345	CDD:227381	47/157 (30%)
		C2H2 Zn finger	217..237	CDD:275368	5/19 (26%)
		C2H2 Zn finger	245..265	CDD:275368	8/46 (17%)
		zf-H2C2_2	257..282	CDD:290200	11/51 (22%)
		C2H2 Zn finger	273..293	CDD:275368	7/19 (37%)
		zf-H2C2_2	286..310	CDD:290200	13/28 (46%)
		C2H2 Zn finger	301..320	CDD:275368	10/23 (43%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	84	1.000	Inparanoid score	I1804
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.050