DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG17568 and CG15436

DIOPT Version :9

Sequence 1:	NP_609951.2	Gene:	CG17568 / 35198	FlyBaseID:	FBgn0032763	Length:	513	Species:	Drosophila melanogaster
Sequence 2:	NP_608840.1	Gene:	CG15436 / 33657	FlyBaseID:	FBgn0031610	Length:	346	Species:	Drosophila melanogaster

Alignment Length:	276	Identity:	74/276 - (26%)
Similarity:	113/276 - (40%)	Gaps:	46/276 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   198 MEDVLDELPQEELSQPRLDSTTSPASMENDVKSEMLDSCEGDDDFLPVDGQLMDLVAVATTPNTL 262
            :||.|..|.:||         ....|.:.|.:   :||....||    ||
  Fly    84 IEDALCALLEEE---------DWEISEDEDAR---IDSASAADD----DG--------------- 117

  Fly   263 ESTAEEKAKRGRMDCEKCGKVYRNRASYEKHLERECRRIERRVKVDKTTTTCDICNKTLSSATAL 327
                :..:|:...:|.:|.|.|:.:.::.:|:         |..:|..:..|..|.:.......|
  Fly   118 ----KSDSKKVAFECRECHKKYQRKGTFLRHM---------RTHMDGQSFPCPYCKRNFRLRVTL 169

  Fly   328 KLHKEGIHQNVKPYICDSCGKQLKTITALNEHKLVHTESRPFECTVCKAGFKNRARLKAHYQIH- 391
            |.|.: .|...|||.|..|.|.....:.|..|:..||..|||:|:.|...|...:.|:.|.:.|
  Fly   170 KAHMK-THNAAKPYECSHCAKTFAQQSTLQSHERTHTGERPFKCSQCSKTFIKSSDLRRHIRTHG 233

  Fly   392 AEPSFVCNICGKKLQTRRTWNMHKVVHTEERRLKCDVCGALFKRSKTLKTHLLSHTGLRPYVCNY 456
            :|..|.|:.|.|....:...:.|...||.||..||..|...|...:.||.|...|...||:.|::
  Fly   234 SERPFKCSKCTKTFTRKFHLDNHFRSHTGERPFKCSHCPKAFAMKQHLKQHSRLHLPDRPFRCSH 298

  Fly   457 CGKSFACNANCRSHKL 472
            |.|:|..::..:.|||
  Fly   299 CPKTFRLSSTLKEHKL 314

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17568	NP_609951.2	zf-AD	10..87	CDD:214871
		COG5048	<313..471	CDD:227381	49/158 (31%)
		C2H2 Zn finger	314..335	CDD:275368	5/20 (25%)
		C2H2 Zn finger	343..363	CDD:275368	5/19 (26%)
		C2H2 Zn finger	371..391	CDD:275368	5/19 (26%)
		C2H2 Zn finger	398..418	CDD:275368	4/19 (21%)
		C2H2 Zn finger	426..446	CDD:275368	6/19 (32%)
		zf-H2C2_2	439..463	CDD:290200	10/23 (43%)
		C2H2 Zn finger	454..475	CDD:275368	7/19 (37%)
CG15436	NP_608840.1	zf-AD	4..78	CDD:285071
		C2H2 Zn finger	128..148	CDD:275368	6/28 (21%)
		C2H2 Zn finger	156..176	CDD:275368	5/20 (25%)
		COG5048	<180..341	CDD:227381	46/135 (34%)
		C2H2 Zn finger	184..204	CDD:275368	5/19 (26%)
		zf-H2C2_2	197..219	CDD:290200	9/21 (43%)
		C2H2 Zn finger	212..232	CDD:275368	5/19 (26%)
		zf-H2C2_2	224..249	CDD:290200	8/24 (33%)
		C2H2 Zn finger	240..260	CDD:275368	4/19 (21%)
		zf-H2C2_2	252..276	CDD:290200	8/23 (35%)
		C2H2 Zn finger	268..288	CDD:275368	6/19 (32%)
		C2H2 Zn finger	296..316	CDD:275368	7/19 (37%)
		C2H2 Zn finger	324..341	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	84	1.000	Inparanoid score	I1804
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24390
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.150