Protein Alignment CG17568 and Zfp212

DIOPT Version :10

• Sequence 1: NP_609951.2
• Gene: CG17568 / 35198
• FlyBaseID: FBgn0032763
• Length: 513
• Species: Drosophila melanogaster
• Sequence 2: NP_001094309.1
• Gene: Zfp212 / 297066
• RGDID: 1307836
• Length: 492
• Species: Rattus norvegicus
• Alignment Length: 480
• Identity: 107/480 - (22%)
• Similarity: 180/480 - (37%)
• Gaps: 71/480 - (14%)

  Fly    24 KVQMNENSQGNWDNVLIMAIRKYFEVQMQLEDELSSVLCT--ECYTLISELIDFAEHVTKVQDIF 86
            ::|..|...|:.:..|....:...|...|||.:. :||.|  :.|.|:...::..|::.:.:: |
  Rat    61 RLQSLEGRAGSAEKKLADFEKTAVEFSNQLEGKW-AVLGTLLQEYGLLQRRLENVENLLRNKN-F 123

  Fly    87 EVLRRTETDGDQEMDVAALRQQFGLCDDDWTHIIKPIPALEMESDNVYQKPAELLKDFPLAETSS 151
            .|||.......:...|:...:..|:|..            |.|.:|:.....||.::.
  Rat   124 WVLRLPPGSKGETPKVSGPLENDGVCFS------------EQEWENLEDWQKELYRNV------- 169

  Fly   152 QEMEISKRTTTTHLIQTKKNVEMEIPKQEFIDLGPILLEKNTSQLDMEDVLDELPQEELSQPRLD 216
              ||.:..|..:..:..:...|:|:..:...|    |:|:.|...|...|..|:..::.....|.
  Rat   170 --MESNYETLVSLKVLGQPEEEVELGAEMVGD----LVEEGTHLADRAMVKQEMLYKQEGPSGLP 228

  Fly   217 STTSPASMENDVKSEMLDSCEGDDDFL----PVDGQLMDLVAVATTPNTLESTAEEKAKRGRMDC 277
            |..|.|:..        .:|.|.:..:    |.|..|::.....:.|.::||:.:....| .:||
  Rat   229 SMFSSAAEP--------QACFGSEQAVFWNSPGDSALLESGPGDSNPESVESSRDPAPGR-NLDC 284

  Fly   278 EKCGKVYRNRASYEKHLERECRRIERRVKVDKTTTTCDICNKTLSSATALKLHKEGIHQNVKPYI 342
            .:..|.:|     :..|.:||.: ..:||.|.:...|..|..:......|..|.:. |.:.:.|.
  Rat   285 PRKQKSHR-----QVQLGQECGQ-GPKVKRDTSPYKCSECQISFRYKQQLTAHLQS-HTSRESYS 342

  Fly   343 CDSCGKQLKTITALNEHKLVHTESRPFECTVCKAGFKNRARLKAHYQIHAE--PSFVCNICGKKL 405
            .....:.|:....|   |.....|:..:|.||...|..:..|..|.:.|.:  ||     ...::
  Rat   343 ATEPEESLRPRPRL---KPQAKRSKLHQCDVCHRSFSCKVSLVTHQRCHQQEGPS-----TSPQI 399

  Fly   406 QTRRTWNM------HKVVHTEERRLKCDVCGALFKRSKTLKTHLLSHTGLRPYVCNYCGKSFACN 464
            |.|.:.|.      |.........|.|..||..|.....|..|...|||.|||.|..|.|||...
  Rat   400 QERFSPNSLVALPGHIPWRKSRSSLICGYCGKSFSHPSDLVRHQRIHTGERPYSCPECEKSFVQK 464

  Fly   465 ANCRSHKLKKHPQEVQQEDGARLPS 489
            .:...|      |::.|.:...|.|
  Rat   465 QHLLQH------QKIHQRERGGLAS 483

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG17568	NP_609951.2	zf-AD	10..87	CDD:214871	14/64 (22%)
		COG5048	<313..471	CDD:227381	41/165 (25%)
		C2H2 Zn finger	314..335	CDD:275368	4/20 (20%)
		C2H2 Zn finger	343..363	CDD:275368	3/19 (16%)
		C2H2 Zn finger	371..391	CDD:275368	6/19 (32%)
		C2H2 Zn finger	398..418	CDD:275368	4/25 (16%)
		C2H2 Zn finger	426..446	CDD:275368	6/19 (32%)
		C2H2 Zn finger	454..475	CDD:275368	6/20 (30%)
Zfp212	NP_001094309.1	KRAB_A-box	142..180	CDD:143639	10/58 (17%)
		C2H2 Zn finger	315..335	CDD:275368	4/20 (20%)
		COG5048	<329..>474	CDD:227381	40/159 (25%)
		C2H2 Zn finger	368..388	CDD:275368	6/19 (32%)
		C2H2 Zn finger	426..446	CDD:275368	6/19 (32%)
		zf-C2H2	426..446	CDD:395048	6/19 (32%)
		zf-H2C2_2	438..463	CDD:463886	13/24 (54%)
		C2H2 Zn finger	454..474	CDD:275368	7/25 (28%)