DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17568 and F58G1.2

DIOPT Version :9

Sequence 1:	NP_609951.2	Gene:	CG17568 / 35198	FlyBaseID:	FBgn0032763	Length:	513	Species:	Drosophila melanogaster
Sequence 2:	NP_001254358.1	Gene:	F58G1.2 / 174931	WormBaseID:	WBGene00010264	Length:	500	Species:	Caenorhabditis elegans

Alignment Length:	430	Identity:	91/430 - (21%)
Similarity:	148/430 - (34%)	Gaps:	112/430 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    95 DGDQEMDVAALRQ-QFGLCDDDWTHIIKPIPALEMESDNVYQKPAELLKDFPLAETSSQEMEISK 158
            |...|:|...:|| |...|..|    :..:||..:..|.:.....:.:....:.:....||.:.:
Worm   123 DPSAELDKCIVRQKQQDFCAPD----LNMVPASSLSIDEIRNAVRKSMFRCKVCKNRFGEMSLLE 183

  Fly   159 RTTTTHLIQTKKNVEMEIPKQ--EFIDLGPILLEKNTSQLDMEDVLDELPQEELSQPRLDSTTS- 220
            |    ||..:.       ||.  .|::          :|.:|.|.:.||.:|   :.|::...|
Worm   184 R----HLRDSH-------PKAYIAFLE----------NQREMADYMGELERE---RNRIEELVSG 224

  Fly   221 ---PASMENDVKSEMLDSCEGDDDFLPVDGQ--------LMDLVAVATTPNTLESTAEEKAKRGR 274
               |...|.:..|..|:.     |.:|:.|:        |.....:....:.|........||.
Worm   225 GFIPPESEIEATSNNLEV-----DSIPLPGENSQGHIPRLNRYGGLMYPMDALRKKFPYLKKRS- 283

  Fly   275 MDCEKCGKVYRNRASYEKHLER---ECRRIERRV--------KVDKTTTTCDI------------ 316
            ..|..|.|.:||..|:..||.:   ||....:.:        ..|..|..||:
Worm   284 PQCPFCDKRFRNDISFNNHLTKKHPECAEFVQCLHCFKCLPSAADLPTHDCDLTYLCLDCRPIRN 348

  Fly   317 -CNKTLSSATALKLHKEGIHQNVKPYICDSCGKQLKTITALNEH-KLVHTESRPFECTVCKAGFK 379
             ||.........|.|: |.|...:   |..|.::..|...|.:| |:.|..||.|:|..|:..|.
Worm   349 MCNGYRLFRHRTKFHR-GYHSGFR---CPDCNQKFLTPRKLRKHRKMAHVFSRTFQCHFCEEFFI 409

  Fly   380 NRARLKAHYQIHAEPSFVCNICGKKLQTRRTWNMHKVVHTEERRLKCDVCGALFKRSKTLKTHLL 444
            :...:                           .:|:.|||...:.:|.||.....|...::.|..
Worm   410 SDTAV---------------------------TIHERVHTGILKFECTVCDFRASRYLQMEEHTK 447

  Fly   445 SHTGLRPYVCNYCGKSFACN--ANCRSHKLKKHPQEVQQE 482
            .|.|   |:|:.|  ...|.  .:.:.|.|.:|...|.:|
Worm   448 EHHG---YMCSVC--QLKCQHWNDIKDHMLAEHSCYVTEE 482

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17568	NP_609951.2	zf-AD	10..87	CDD:214871
		COG5048	<313..471	CDD:227381	36/173 (21%)
		C2H2 Zn finger	314..335	CDD:275368	7/33 (21%)
		C2H2 Zn finger	343..363	CDD:275368	6/20 (30%)
		C2H2 Zn finger	371..391	CDD:275368	3/19 (16%)
		C2H2 Zn finger	398..418	CDD:275368	1/19 (5%)
		C2H2 Zn finger	426..446	CDD:275368	5/19 (26%)
		zf-H2C2_2	439..463	CDD:290200	6/23 (26%)
		C2H2 Zn finger	454..475	CDD:275368	5/22 (23%)
F58G1.2	NP_001254358.1	bZIP	<186..222	CDD:304365	11/55 (20%)
		C2H2 Zn finger	372..393	CDD:275368	6/20 (30%)
		C2H2 Zn finger	401..421	CDD:275368	4/46 (9%)
		C2H2 Zn finger	429..449	CDD:275368	5/19 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000