DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17568 and ztf-23

DIOPT Version :9

Sequence 1:	NP_609951.2	Gene:	CG17568 / 35198	FlyBaseID:	FBgn0032763	Length:	513	Species:	Drosophila melanogaster
Sequence 2:	NP_491096.1	Gene:	ztf-23 / 171880	WormBaseID:	WBGene00021846	Length:	419	Species:	Caenorhabditis elegans

Alignment Length:	374	Identity:	90/374 - (24%)
Similarity:	144/374 - (38%)	Gaps:	84/374 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   143 DFPLAETSSQEMEISKRTTTTHLIQTKKNVE--------------MEIPKQEFID-------LGP 186
            |||.....|.....::..:...:::.|:|:|              :||.:....|       |.|
Worm    43 DFPALSAISLMDHFAQNHSDVAIVEFKRNLEDEKRFRKMVADSIAIEIDETSQQDSSTQMTVLQP 107

  Fly   187 ILLEKNTSQLDMEDVLDELPQE-----ELSQPRLDSTTSPASMENDVKSEMLDSCEGDDDFLPVD 246
             ::::.|:|:.:      ||.|     |:...|.........:::|...|.|...:.|||::...
Worm   108 -MMQQGTAQMIL------LPPEGSQYDEIVDHRGPDEDDFGVLDDDENIEELIDDDDDDDYIDEL 165

  Fly   247 GQLMDLVAVATTPNTLESTAEEKAKRGRMDCEKCGKVYRNRASYEKHLER-ECRRIER---RVKV 307
            |..:.:.|...:...||.           |....|.:   |:|...||:. ..||:::   .|.|
Worm   166 GNPVFIGAHDDSDYILED-----------DLSPQGPI---RSSNNYHLKYIRTRRMDKLIDNVVV 216

  Fly   308 DKTTTTCDICNKTLSSATALKLHKEGIHQNVK--PYICDSCGKQLKTITALNEHKLVHTESRPFE 370
            :.|...........:|..|.   .:|...:.|  .:.||.|.:..|..:.|:||:..|...:||:
Worm   217 NATQRDSPEQEDCSTSGVAF---ADGQTNSGKMGRFSCDRCSRTFKYQSKLDEHRRTHLGVKPFQ 278

  Fly   371 CTVCKAGFKNRARLKAHYQIH-AEPSFVCNICGKKLQTRRTWNMHKVVHTEERRLKCDVCGALFK 434
            |..|...|..|..||.|.::| .|..|||.           |.                ||..|.
Worm   279 CHYCTRQFSQRGALKTHMRLHTGERPFVCQ-----------WE----------------CGKQFA 316

  Fly   435 RSKTLKTHLLSHTGLRPYVCNYCGKSFACNANCRSHKLKKHPQEVQQED 483
            .|.....|..:|:|.|||:||.|||||..|::...|....|.:|:.|:|
Worm   317 SSSAKSHHEKTHSGERPYICNVCGKSFTKNSHVIRHLKNIHNRELAQQD 365

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17568	NP_609951.2	zf-AD	10..87	CDD:214871
		COG5048	<313..471	CDD:227381	45/160 (28%)
		C2H2 Zn finger	314..335	CDD:275368	3/20 (15%)
		C2H2 Zn finger	343..363	CDD:275368	7/19 (37%)
		C2H2 Zn finger	371..391	CDD:275368	7/19 (37%)
		C2H2 Zn finger	398..418	CDD:275368	2/19 (11%)
		C2H2 Zn finger	426..446	CDD:275368	5/19 (26%)
		zf-H2C2_2	439..463	CDD:290200	13/23 (57%)
		C2H2 Zn finger	454..475	CDD:275368	9/20 (45%)
ztf-23	NP_491096.1	C2H2 Zn finger	251..271	CDD:275368	7/19 (37%)
		zf-H2C2_2	264..288	CDD:290200	9/23 (39%)
		C2H2 Zn finger	279..299	CDD:275368	7/19 (37%)
		zf-H2C2_2	291..317	CDD:290200	12/52 (23%)
		C2H2 Zn finger	307..328	CDD:275368	7/47 (15%)
		zf-H2C2_2	324..344	CDD:290200	12/19 (63%)
		C2H2 Zn finger	336..357	CDD:275368	9/20 (45%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000