DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17568 and ZNF524

DIOPT Version :9

Sequence 1:	NP_609951.2	Gene:	CG17568 / 35198	FlyBaseID:	FBgn0032763	Length:	513	Species:	Drosophila melanogaster
Sequence 2:	XP_011524789.1	Gene:	ZNF524 / 147807	HGNCID:	28322	Length:	370	Species:	Homo sapiens

Alignment Length:	181	Identity:	49/181 - (27%)
Similarity:	70/181 - (38%)	Gaps:	35/181 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   320 TLSSATALKLHKEGIHQNVKPYICDSCGKQLKTITALNEHKLVHTESRPFECTVCKAGFKNRARL 384
            |:|..:|  ...||......|:.|..|.:....::.|..|.:.|:|.:|.:|.||...||..:.|
Human   201 TVSEGSA--AGPEGSGPRKAPHFCPVCLRAFPYLSDLERHSISHSELKPHQCKVCGKTFKRSSHL 263

  Fly   385 KAHYQIHAEPSFVCNICGKKLQTRRTWNMHKVVHTEERRLKCDVCGALFKRSKTLKTHLLSHTGL 449
            :.|          |||                 |...|..:|.:|...|:.:..|..|...|:|.
Human   264 RRH----------CNI-----------------HAGLRPFRCPLCPRRFREAGELAHHHRVHSGE 301

  Fly   450 RPYVCNYCGKSFACNANCRSHKLKKHPQEVQQEDGARL--PSRLNVPTLDE 498
            |||.|..|...|......|.|..:|||:.:    |..|  |...:.|..||
Human   302 RPYQCPICRLRFTEANTLRRHAKRKHPEAM----GVPLCAPDPGSEPPWDE 348

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17568	NP_609951.2	zf-AD	10..87	CDD:214871
		COG5048	<313..471	CDD:227381	39/150 (26%)
		C2H2 Zn finger	314..335	CDD:275368	5/14 (36%)
		C2H2 Zn finger	343..363	CDD:275368	4/19 (21%)
		C2H2 Zn finger	371..391	CDD:275368	7/19 (37%)
		C2H2 Zn finger	398..418	CDD:275368	3/19 (16%)
		C2H2 Zn finger	426..446	CDD:275368	5/19 (26%)
		zf-H2C2_2	439..463	CDD:290200	10/23 (43%)
		C2H2 Zn finger	454..475	CDD:275368	5/20 (25%)
ZNF524	XP_011524789.1	COG5048	<219..>283	CDD:227381	22/90 (24%)
		C2H2 Zn finger	222..242	CDD:275368	4/19 (21%)
		zf-H2C2_2	234..259	CDD:290200	9/24 (38%)
		C2H2 Zn finger	250..270	CDD:275368	10/46 (22%)
		zf-H2C2_2	262..285	CDD:290200	9/49 (18%)
		C2H2 Zn finger	278..298	CDD:275368	5/19 (26%)
		zf-H2C2_2	290..314	CDD:290200	9/23 (39%)
		C2H2 Zn finger	306..327	CDD:275368	5/20 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910