DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG17568 and znf335

DIOPT Version :10

Sequence 1:NP_609951.2 Gene:CG17568 / 35198 FlyBaseID:FBgn0032763 Length:513 Species:Drosophila melanogaster
Sequence 2:XP_005167155.1 Gene:znf335 / 100148891 ZFINID:ZDB-GENE-130530-814 Length:1534 Species:Danio rerio


Alignment Length:522 Identity:113/522 - (21%)
Similarity:181/522 - (34%) Gaps:155/522 - (29%)


- Green bases have known domain annotations that are detailed below.


  Fly    88 VLRRTETDGDQEMDVAALRQQFGLCDDDWTHIIKPIPALEMESDNVYQKPAELLKDFPLAETSSQ 152
            |:::.|...::|.|:.    ..|..||              :.|:.| |||:        |.:..
Zfish   519 VVKKEEQPEEEEDDIV----DAGALDD--------------QGDSDY-KPAD--------EEARS 556

  Fly   153 EMEISKRT-------TTTHLIQTKKNVEMEIPKQEFIDLGPILLEKNTSQLDMEDVLDELPQEEL 210
            .:.:|..|       ::......|:...|..|.::|:...    |...:..:..:..|....||.
Zfish   557 RLAVSHFTPPPSCSSSSPASTSRKRPRRMVGPPRKFLPDS----ESPAAPSETNNTEDPQAPEEA 617

  Fly   211 SQPRLDSTTSPASMENDVKSEMLDSCEGDDDFLPVDGQLMDLVAVATTPNTLESTAEEKAKRGRM 275
            |...||:.:|..|...:|:..:..|          |.:..| .:..|:|:.||...:::.:..:.
Zfish   618 SSSGLDNGSSSFSNGTEVEPGVSQS----------DSENRD-PSSNTSPDDLEFLPKKRGRPSKR 671

  Fly   276 DCEKCGKVYRNRASYEKHLERECRRIERRVKVDKTTTTCDICNKTLSSATALKLH---------- 330
            ..:|..|.|.||..|.:.|:...|           ...|.||.....|...||.|          
Zfish   672 FLQKKYKKYMNRNKYYRSLKPLLR-----------PHNCWICGSRFLSQEDLKFHVDSHEGNDPE 725

  Fly   331 -----------------KEGI--HQNVKPYICDSCGKQLKTITALNEHKLVHTESR--------- 367
                             ||.:  |:..|||.|:.|.........:..|..||.:|:         
Zfish   726 RYKCLQCSYRCKRWSSLKEHMFNHEGTKPYKCEMCDYTSVYKKDVTRHSAVHNKSKSRKIDVSCV 790

  Fly   368 ---------PFECTVCKAGFKNRARLKAHYQIHA-EPSFVCNICGKKLQTRRTWNMHKVVHTE-- 420
                     .|.|.:|...:..:.||..|.:.|: |...:|:.|||..:.|.|:.||.:.|.:  
Zfish   791 NPSQVSKVSEFPCPICSRVYPMQKRLTQHMKTHSTEKPHMCDKCGKSFKKRYTFKMHLLTHIQNC 855

  Fly   421 -ERRLKCDVCGALFKRSKTLKTHLLSHTGLRPYVCNYC--------------------GKSFAC- 463
             ....||:.|.......|.|..|.||||..:|:.|..|                    .|.|:| 
Zfish   856 GNSLFKCEFCDYTCNDKKHLLNHQLSHTNDKPFKCEECKYSTSKEDFLVSHIAIKHTGEKPFSCE 920

  Fly   464 --------NANCRSHKLKKHPQEVQQEDGARL----PSR------LNVPTLDELRVM--TQKLPK 508
                    ..|.|.|...:||:..  |:.:|.    |.|      ..|..::|||:.  ||:. :
Zfish   921 MCHFTTRHRKNLRLHVQCRHPETF--EEWSRTHPDEPVRRRQTPVFTVEQIEELRLQHETQEF-Q 982

  Fly   509 GT 510
            ||
Zfish   983 GT 984

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG17568NP_609951.2 zf-AD 10..87 CDD:214871
COG5048 <313..471 CDD:227381 54/237 (23%)
C2H2 Zn finger 314..335 CDD:275368 9/49 (18%)
C2H2 Zn finger 343..363 CDD:275368 3/19 (16%)
C2H2 Zn finger 371..391 CDD:275368 5/19 (26%)
C2H2 Zn finger 398..418 CDD:275368 8/19 (42%)
C2H2 Zn finger 426..446 CDD:275368 6/19 (32%)
C2H2 Zn finger 454..475 CDD:275368 8/49 (16%)
znf335XP_005167155.1 COG5048 <592..838 CDD:227381 57/271 (21%)
C2H2 Zn finger 699..719 CDD:275368 7/19 (37%)
C2H2 Zn finger 729..749 CDD:275368 2/19 (11%)
zf-H2C2_2 741..766 CDD:463886 8/24 (33%)
zf-H2C2_5 755..779 CDD:404746 6/23 (26%)
C2H2 Zn finger 803..823 CDD:275368 5/19 (26%)
zf-H2C2_2 815..840 CDD:463886 9/24 (38%)
C2H2 Zn finger 831..851 CDD:275368 8/19 (42%)
C2H2 Zn finger 862..882 CDD:275368 6/19 (32%)
C2H2 Zn finger 890..911 CDD:275368 2/20 (10%)
C2H2 Zn finger 919..936 CDD:275368 3/16 (19%)
rne <1073..1165 CDD:236766
C2H2 Zn finger 1215..1235 CDD:275370
SFP1 <1236..1320 CDD:227516
C2H2 Zn finger 1243..1263 CDD:275368
zf-H2C2_5 1269..1293 CDD:404746
C2H2 Zn finger 1271..1291 CDD:275368
zf-H2C2_2 1283..1308 CDD:463886
C2H2 Zn finger 1299..1320 CDD:275368
Blue background indicates that the domain is not in the aligned region.

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