DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17568 and zfp64

DIOPT Version :9

Sequence 1:	NP_609951.2	Gene:	CG17568 / 35198	FlyBaseID:	FBgn0032763	Length:	513	Species:	Drosophila melanogaster
Sequence 2:	NP_001373446.1	Gene:	zfp64 / 100003733	ZFINID:	ZDB-GENE-031118-80	Length:	642	Species:	Danio rerio

Alignment Length:	274	Identity:	67/274 - (24%)
Similarity:	107/274 - (39%)	Gaps:	46/274 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   223 SMENDVKSEMLDSCEGDDDFLPVDGQLMDLVAVATTPNTLESTAEEKAKR-------GRMDCEKC 280
            |:.|...||.|.:|                  |:....||....:..:|:       .|..|...
Zfish    52 SVRNAGASESLQTC------------------VSKVKKTLTKAQKNPSKKLKPALTQKRHICTFS 98

  Fly   281 GKVYRNRASYEKHLEREC------RRIERRVKVDKTTTTCDICNKTLSSATALKLHKEGIHQNVK 339
            |..::.:.. :|.:||..      |..|           |::|:|..|....|.||.. :|...|
Zfish    99 GCTFKTQYG-QKDMERHILTHTGERPFE-----------CELCHKRFSRRDKLNLHSR-LHTGEK 150

  Fly   340 PYICDSCGKQLKTITALNEHKLVHTESRPFECTVCKAGFKNRARLKAHYQIH-AEPSFVCNICGK 403
            |:.|..|.......::|.:|..:|.:.|||:|.:|....:|.::|..|.:.| .:..|.||.|..
Zfish   151 PHKCKYCTYAAADSSSLKKHLRIHYDERPFKCQICPYASRNSSQLTVHLRSHTGDAPFQCNQCDA 215

  Fly   404 KLQTRRTWNMHKVVHTEERRLKCDVCGALFKRSKTLKTHL-LSHTGLRPYVCNYCGKSFACNANC 467
            |.:.......|..||:.|:..|||:|.........||:|: |.|:....:.|:.|....:..|..
Zfish   216 KFKINSDLKRHSRVHSGEKPYKCDLCDYRCAMKANLKSHVHLKHSASDSFHCSKCDFQCSTKAAL 280

  Fly   468 RSHKLKKHPQEVQQ 481
            |.|..:..|.:..|
Zfish   281 RHHSRQHQPAQPLQ 294

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17568	NP_609951.2	zf-AD	10..87	CDD:214871
		COG5048	<313..471	CDD:227381	46/159 (29%)
		C2H2 Zn finger	314..335	CDD:275368	7/20 (35%)
		C2H2 Zn finger	343..363	CDD:275368	4/19 (21%)
		C2H2 Zn finger	371..391	CDD:275368	5/19 (26%)
		C2H2 Zn finger	398..418	CDD:275368	5/19 (26%)
		C2H2 Zn finger	426..446	CDD:275368	7/20 (35%)
		zf-H2C2_2	439..463	CDD:290200	7/24 (29%)
		C2H2 Zn finger	454..475	CDD:275368	5/20 (25%)
zfp64	NP_001373446.1	C2H2 Zn finger	95..118	CDD:275368	5/23 (22%)
		zf-H2C2_2	110..135	CDD:404364	7/35 (20%)
		C2H2 Zn finger	126..146	CDD:275368	7/20 (35%)
		zf-H2C2_2	139..162	CDD:404364	8/23 (35%)
		C2H2 Zn finger	154..174	CDD:275368	4/19 (21%)
		SFP1	<176..260	CDD:227516	26/83 (31%)
		C2H2 Zn finger	182..202	CDD:275368	5/19 (26%)
		C2H2 Zn finger	210..230	CDD:275368	5/19 (26%)
		zf-H2C2_2	222..246	CDD:404364	8/23 (35%)
		C2H2 Zn finger	238..257	CDD:275368	6/18 (33%)
		C2H2 Zn finger	323..341	CDD:275368
		C2H2 Zn finger	384..404	CDD:275368
		SP1-4_N	<408..>605	CDD:425404
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170577393
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.930