DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment brat and PSH1

DIOPT Version :9

Sequence 1:	NP_001188842.2	Gene:	brat / 35197	FlyBaseID:	FBgn0010300	Length:	1061	Species:	Drosophila melanogaster
Sequence 2:	NP_014587.1	Gene:	PSH1 / 854102	SGDID:	S000005415	Length:	406	Species:	Saccharomyces cerevisiae

Alignment Length:	120	Identity:	23/120 - (19%)
Similarity:	45/120 - (37%)	Gaps:	26/120 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   197 QSYLCANCVTAHEFMH------CFNGHNVC--LIKGFEASTTGTPLSVGSPSNNPASNEFKYASS 253
            :|.:|:.|   |::|.      |  |||.|  .:..:.||.|...|:...     ..::.....:
Yeast    26 ESLVCSIC---HDYMFVPMMTPC--GHNYCYGCLNTWFASNTQKELACPQ-----CRSDITTIPA 80

  Fly   254 LTMMLQQQQQLDSQQQQQQQQLLPAQPMSQLSKIVLAAAAQANSQEQQRE-DSIY 307
            |...|||......::.:.|..       ....|::.....:.|..:..:| |:::
Yeast    81 LNTTLQQYLSFILEKLRDQND-------ESFKKLLTTKTKEENDYKNDKEKDTLF 128

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
brat	NP_001188842.2	BBOX	176..222	CDD:197662	10/32 (31%)
		zf-B_box	328..366	CDD:279037
		NHL_brat_like	760..1030	CDD:271329
		NHL repeat	783..819	CDD:271329
		NHL repeat	830..871	CDD:271329
		NHL repeat	874..910	CDD:271329
		NHL repeat	914..954	CDD:271329
		NHL repeat	959..997	CDD:271329
		NHL repeat	1002..1027	CDD:271329
PSH1	NP_014587.1	RING-HC_ScPSH1_like	29..72	CDD:319482	13/52 (25%)
PSH1	NP_014587.1	DNA_RNApol_7kD	149..>175	CDD:412622
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2677
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.030