DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment brat and emb1974

DIOPT Version :9

Sequence 1:	NP_001188842.2	Gene:	brat / 35197	FlyBaseID:	FBgn0010300	Length:	1061	Species:	Drosophila melanogaster
Sequence 2:	NP_187362.3	Gene:	emb1974 / 819892	AraportID:	AT3G07060	Length:	774	Species:	Arabidopsis thaliana

Alignment Length:	416	Identity:	76/416 - (18%)
Similarity:	144/416 - (34%)	Gaps:	120/416 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly   608 SLHGLGLGLSGASLLDSSSSAGGAVGAFS--------------NGGLLLGGRDRNALAVEQHFGE 658
            |||     |...|.|.|...:....|.|.              :|.:.:|.:    ..|||.|..
plant     5 SLH-----LKKISWLSSRILSDNVHGRFRRSITTPATCLAPSLDGDMNIGSK----TLVEQRFSR 60

  Fly   659 LMPKRGGGGYTGSNGSATSAVAHYN--------------PYEKWSNG--GSDNLFSSVTSGVSGS 707
            ............|:.|::.:..|.:              |...|.|.  |:..||..
plant    61 GFASVRRVSRASSSSSSSPSSPHVDLLSFIKASLDKLEGPSHHWLNRDFGNKQLFKD-------- 117

  Fly   708 SAVADAFASLSAVGGSVVSGAGAGGSTVSSESLLDLTNKLLSATIYPPKSQIKRQKMIYHCKFGE 772
                         .|:.|..||         .|||.|:.|..   :..|.::.:|:....|..|.
plant   118 -------------KGTYVVLAG---------HLLDGTSDLSG---FFEKLKLLQQRSPGVCFMGI 157

  Fly   773 FGVMEGQFTEPSGVAVN--AQNDIIVADTNNHRIQIFDKEGRFKFQFGECGK---RD--SQLLYP 830
                  .|::.:.:|.:  |..::|:.:.....:.:.:||  |....||...   :|  :.|:|.
plant   158 ------HFSDQARIADDRTALAELILKEYLTFPVLLSEKE--FPKTSGEVRYIVFKDFKNPLIYE 214

  Fly   831 NR----VAVVRNSGDIIVTERSPTHQIQIYN----------QYGQFVRKFGATILQHPRGVTVDN 881
            .:    .:||:....::..:...:..::::.          :...|...|...:|..|..::.|.
plant   215 EKDLDIASVVKALDSLLTQDTEKSKSVRLFTNTWSKQAEAIKESHFPSFFQDLLLYFPGCISADE 279

  Fly   882 KG-RIIVVECKVMRVIIFDQNGNVLHKFGC----------SKHLEFPNGVVVNDKQE-IFISDNR 934
            .| |:.:.:....|:|||:.:|.::...||          |..:..|.|.:.::.:: ::|.|:.
plant   280 VGDRLFLSDTNHHRIIIFENSGKIVDSIGCFPGFEDGDFESAKMLRPTGTLYDEAEDCLYIVDSE 344

  Fly   935 AHCVKVFNYEGQYLRQIGGEGITNYP 960
            .|.::..|...:.|.       |.||
plant   345 NHAIRRANINSRVLE-------TVYP 363

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
brat	NP_001188842.2	BBOX	176..222	CDD:197662
		zf-B_box	328..366	CDD:279037
		NHL_brat_like	760..1030	CDD:271329	42/234 (18%)
		NHL repeat	783..819	CDD:271329	6/37 (16%)
		NHL repeat	830..871	CDD:271329	4/54 (7%)
		NHL repeat	874..910	CDD:271329	9/36 (25%)
		NHL repeat	914..954	CDD:271329	7/40 (18%)
		NHL repeat	959..997	CDD:271329	2/2 (100%)
		NHL repeat	1002..1027	CDD:271329
emb1974	NP_187362.3	NHL	<264..>361	CDD:302697	21/103 (20%)
		NHL repeat	272..309	CDD:271320	9/36 (25%)
		NHL repeat	318..361	CDD:271320	8/49 (16%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24104
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100