Protein Alignment brat and trim45

DIOPT Version :9

• Sequence 1: NP_001188842.2
• Gene: brat / 35197
• FlyBaseID: FBgn0010300
• Length: 1061
• Species: Drosophila melanogaster
• Sequence 2: NP_001011026.1
• Gene: trim45 / 496435
• XenbaseID: XB-GENE-997848
• Length: 547
• Species: Xenopus tropicalis
• Alignment Length: 557
• Identity: 103/557 - (18%)
• Similarity: 170/557 - (30%)
• Gaps: 178/557 - (31%)

  Fly   166 SSSNTSANGSPPRCTACKSK-CSDAVAKCFECQSYLCANCVTAHE-FMHCFNGHNVCLIKGFEAS 228
            :.|...|.|. .:|..|:.. |...:..|...   ||..|:...| |.....||
 Frog     4 NGSRKEAQGR-TQCPQCQQPFCQPRILPCLHT---LCGGCLAKLEPFSALGKGH----------- 53

  Fly   229 TTGTPLSVGSPSNN-----PASNEFK----YASSLTMMLQQQQQ------LDSQQQQQQQQLLPA 278
            :.||..||..|..:     ||....:    :.:...::|.|.|.      .|..::.|      |
 Frog    54 SAGTHWSVLCPVCDSEVALPAGGVEELLPDWLAEAEVLLAQVQSGGLALPCDLCREGQ------A 112

  Fly   279 QPMSQLSKI-VLAAAAQANSQEQQREDSIYGSLHPQQQQQQQQQQQRQLFCPRHKQELLKFSCRT 342
            :...|..|: |.....||:.::::   :....|||.|.............|..|..|.|...|..
 Frog   113 EKRCQECKVNVCEFCCQAHRRQKR---TAAHPLHPLQDLSLGTILPPAPCCTLHPLEALGLFCEP 174

  Fly   343 CCILVCKECIVLEHSTGLHELENVQSPGMTTSTGSTANESALQTL------LADMRGKIGEI--- 398
            |.:..|::|.:..|..  |:|.    |....:.|.  .||.|:.|      :..:...:|.:
 Frog   175 CTVPCCRDCAIGHHRG--HDLR----PAAECAGGH--RESLLRALQEAEPHIEQLEAALGGVQEA 231

  Fly   399 --------VGIAGNSD---QNLTKVKLQYQKA-HNELNETHQFFASMLDERKTELLKELETLYTA 451
                    :|:....:   :...:..|:::.| ..::.|..|....:|..||.:|.::|..|.||
 Frog   232 GKALGQRALGLRAEVEAFIEGYVRAVLEHKAALLRDIEEETQRRQQVLALRKAQLQQQLLDLRTA 296

  Fly   452 K------------------------------------VNSNN-------SWQQRSR--------- 464
            .                                    .:.||       .|::...
 Frog   297 SGFTRDLVARGPDLHLLQAQGLALTRLKELNQGAPRAADQNNPAGIQFSPWEEAGLCQGYQMQGV 361

  Fly   465 ---DLIDKGLATCEA--------VERSPA------------------PPSSLLTEALLLRKSLEQ 500
               ...|.|  .|||        .:..||                  |||     ..::.|..::
 Frog   362 LQVKAADPG--KCEARGAGLQSVCQGQPASFTFFCRTASGDPVLGGQPPS-----VTIVHKDTDR 419

  Fly   501 QLQTGIQEMQLPFEIEFMSNYQSIQAGVRNTFGYIRANSSDGGPTGMSLTSNGHGKQPPIARPTQ 565
            .|...||:.|   :..|..:|.:.:.|..:....:|...:.|.|..:.:..... :.|.|.....
 Frog   420 SLHPSIQDNQ---DGTFHISYLAPEPGELSISVSLRGQHTPGSPFSVKVRGKSQ-RHPGIYHCCT 480

  Fly   566 SASNSSASSA---------------GSGHHGHHQQSH 587
            ..|:.....|               |.||.||..|||
 Frog   481 FCSSGGQKEARCGCGGTMPGGYQGCGHGHKGHPGQSH 517

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
brat	NP_001188842.2	BBOX	176..222	CDD:197662	11/47 (23%)
		zf-B_box	328..366	CDD:279037	11/37 (30%)
		NHL_brat_like	760..1030	CDD:271329
		NHL repeat	783..819	CDD:271329
		NHL repeat	830..871	CDD:271329
		NHL repeat	874..910	CDD:271329
		NHL repeat	914..954	CDD:271329
		NHL repeat	959..997	CDD:271329
		NHL repeat	1002..1027	CDD:271329
trim45	NP_001011026.1	RING-HC_TRIM45-C-VII	14..69	CDD:319502	16/68 (24%)
		Bbox1_TRIM45_C-X	102..145	CDD:380867	10/51 (20%)
		zf-B_box	155..195	CDD:395518	11/45 (24%)
		BBC	203..>279	CDD:128778	10/77 (13%)
		Filamin	366..461	CDD:395505	20/104 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D489543at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010