DRSC/TRiP Functional Genomics Resources

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Protein Alignment brat and NHLRC3

DIOPT Version :9

Sequence 1:NP_001188842.2 Gene:brat / 35197 FlyBaseID:FBgn0010300 Length:1061 Species:Drosophila melanogaster
Sequence 2:NP_001012772.1 Gene:NHLRC3 / 387921 HGNCID:33751 Length:347 Species:Homo sapiens


Alignment Length:261 Identity:55/261 - (21%)
Similarity:83/261 - (31%) Gaps:102/261 - (39%)


- Green bases have known domain annotations that are detailed below.


  Fly   656 FGELMPKRGGGGYTGSNGSATSAVAHYNPYEKWSNGGSDNLFSSVTSGVSGSSAVADAFASLSAV 720
            ||:|:...   |..|..|::.:.:...||.|.:                     |.|.       
Human   141 FGDLVQVL---GTPGKKGTSLNPLQFDNPAELY---------------------VEDT------- 174

  Fly   721 GGSVVSGAGAGGSTVSSESLLDLTNKLLSATIYPPKSQIKRQKMIYHCKFGEFGVMEGQFTEPSG 785
             |.:....|.||          |.|:|:..:          |..:.....||.|....:|..|..
Human   175 -GDIYIVDGDGG----------LNNRLIKLS----------QDFMILWLHGENGTGPAKFNIPHS 218

  Fly   786 VAVNAQNDIIVADTNNHRIQIFDK---------------EGRFKFQF------------------ 817
            |.:::...:.|||..|.|||:|||               ||....:|                  
Human   219 VTLDSAGRVWVADRGNKRIQVFDKDTGEWLGAWNNCFTEEGPSSVRFTPDGKYLIVAQLNLSRLS 283

  Fly   818 ----------GECG-----KRDSQLLYPNRVAVVRNSGDIIVTERSPTHQIQIYNQYGQFVRKFG 867
                      |||.     :...|:| |:.:.|.|.:|.:.|.|.. ..|:|.|.....:|..||
Human   284 VVAAPPVGSIGECSVISTIQLADQVL-PHLLEVDRKTGAVYVAEIG-AKQVQKYVPLNSYVPSFG 346

  Fly   868 A 868
            :
Human   347 S 347

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
bratNP_001188842.2 BBOX 176..222 CDD:197662
zf-B_box 328..366 CDD:279037
NHL_brat_like 760..1030 CDD:271329 37/157 (24%)
NHL repeat 783..819 CDD:271329 15/78 (19%)
NHL repeat 830..871 CDD:271329 12/39 (31%)
NHL repeat 874..910 CDD:271329
NHL repeat 914..954 CDD:271329
NHL repeat 959..997 CDD:271329
NHL repeat 1002..1027 CDD:271329
NHLRC3NP_001012772.1 NHL 1 47..93
NHL 66..336 CDD:302697 51/248 (21%)
NHL repeat 107..153 CDD:271320 4/14 (29%)
NHL 2 150..196 14/94 (15%)
NHL repeat 166..205 CDD:271320 12/87 (14%)
NHL 3 200..243 15/42 (36%)
NHL repeat 213..250 CDD:271320 13/36 (36%)
NHL repeat 258..295 CDD:271320 3/36 (8%)
NHL 4 294..338 14/45 (31%)
NHL repeat 308..335 CDD:271320 9/28 (32%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D489543at2759
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
11.010

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