DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment brat and nhlrc3

DIOPT Version :9

Sequence 1:	NP_001188842.2	Gene:	brat / 35197	FlyBaseID:	FBgn0010300	Length:	1061	Species:	Drosophila melanogaster
Sequence 2:	XP_002936773.2	Gene:	nhlrc3 / 100497010	XenbaseID:	XB-GENE-988782	Length:	344	Species:	Xenopus tropicalis

Alignment Length:	170	Identity:	43/170 - (25%)
Similarity:	80/170 - (47%)	Gaps:	26/170 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   876 GVTVDNKGRIIVVECK---VMRVIIFDQNGNVLHKFGCSKHLEFPNGV--VVNDKQ-EIFISD-- 932
            ||.||....::.|..:   |.:|::|.:.|....::. :..::.|:|:  |..||: .|:|:|
Frog    68 GVAVDPTNSLVYVAQRGENVSKVLVFTEEGYFKQQWN-TDSIDMPHGIFAVSTDKEHSIWITDVG 131

  Fly   933 --NRAHCVKVFNYEGQYLRQIGGEGIT---------NYPIGVGINSNGEILIADNHNNFNLTI-- 984
              |..|.||.::..|:.|:.:|..|.:         :.|..:.:.::|::.|.|.....|..|
Frog   132 QGNFGHTVKKYSPSGKLLQVLGTAGKSGSALDPLQFDQPAEIFVENSGDLYIVDGDGGLNNRILK 196

  Fly   985 FTQDGQLISALESK-VKHAQCF---DVALMDDGSVVLASK 1020
            ||:|..|:..|..: .|..|.|   .|.:.:.|.|.:|.:
Frog   197 FTKDFWLLWTLGGRGTKPGQFFIPHSVTVDEVGRVWVADR 236

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
brat	NP_001188842.2	BBOX	176..222	CDD:197662
		zf-B_box	328..366	CDD:279037
		NHL_brat_like	760..1030	CDD:271329	43/170 (25%)
		NHL repeat	783..819	CDD:271329
		NHL repeat	830..871	CDD:271329
		NHL repeat	874..910	CDD:271329	9/36 (25%)
		NHL repeat	914..954	CDD:271329	15/46 (33%)
		NHL repeat	959..997	CDD:271329	11/39 (28%)
		NHL repeat	1002..1027	CDD:271329	6/22 (27%)
nhlrc3	XP_002936773.2	NHL	52..340	CDD:302697	43/170 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D489543at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010