DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment brat and rnf152

DIOPT Version :9

Sequence 1:	NP_001188842.2	Gene:	brat / 35197	FlyBaseID:	FBgn0010300	Length:	1061	Species:	Drosophila melanogaster
Sequence 2:	XP_004915369.1	Gene:	rnf152 / 100486837	XenbaseID:	XB-GENE-1001845	Length:	203	Species:	Xenopus tropicalis

Alignment Length:	158	Identity:	27/158 - (17%)
Similarity:	54/158 - (34%)	Gaps:	49/158 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly   177 PRCTACKSKCSDAVAKCFECQSYL--------CANC--VT----AHEFMHCFNGHNVCLIKGFEA 227
            |:...||..|      |..|...:        |..|  ||    .:......:..:|..:.....
Frog    25 PKLLDCKHTC------CSVCLQQMRASQKDLRCPWCRGVTKLPPGYSVSQLPDDPDVVAVIAIPH 83

  Fly   228 STTGTPLSVGSPSNN------PAS-----------------NEFKYASSLTMMLQQQ------QQ 263
            ::..||:.:..|||.      |.|                 |:.|..:.:||.::|.      .|
Frog    84 ASENTPVFIKLPSNGCYMWPLPVSKERALLPGDIGCRLLPGNQQKPVTVVTMPMEQHPLHGNISQ 148

  Fly   264 LDSQQQQQQQQLLPAQPMSQLSKIVLAA 291
            ...:::.:::.::.:...|.:..::|.|
Frog   149 DIVEEEHERRGVVKSSTWSGVCTVILVA 176

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
brat	NP_001188842.2	BBOX	176..222	CDD:197662	11/58 (19%)
		zf-B_box	328..366	CDD:279037
		NHL_brat_like	760..1030	CDD:271329
		NHL repeat	783..819	CDD:271329
		NHL repeat	830..871	CDD:271329
		NHL repeat	874..910	CDD:271329
		NHL repeat	914..954	CDD:271329
		NHL repeat	959..997	CDD:271329
		NHL repeat	1002..1027	CDD:271329
rnf152	XP_004915369.1	RING-HC_RNF152	11..55	CDD:319462	7/35 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D489543at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010