DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment DCTN6-p27 and Dctn6

DIOPT Version :9

Sequence 1:	NP_609949.1	Gene:	DCTN6-p27 / 35195	FlyBaseID:	FBgn0086446	Length:	185	Species:	Drosophila melanogaster
Sequence 2:	XP_006509157.1	Gene:	Dctn6 / 22428	MGIID:	1343154	Length:	208	Species:	Mus musculus

Alignment Length:	193	Identity:	85/193 - (44%)
Similarity:	118/193 - (61%)	Gaps:	22/193 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 SENRIKILPKAVVCEESSLRGDIT------------------FSSGCVVHPSATVIADAGPIIIG 49
            ::..:||.|.||||.||.:|||:|                  |....|:||.|.:||:|||||||
Mouse     5 TQKSVKIAPGAVVCVESEIRGDVTIECMWLSSPLRRNTSSQLFCPRTVIHPKARIIAEAGPIIIG 69

  Fly    50 ENCIIEEYATVAHRLEPGAVWDVNNI----LSIGTHNVFEVGCQVEAAKIGDKNVFESKCYVGPG 110
            |..:|||.|.:.:......:.|..:.    :.|||:|||||||..:|.|:||.||.|||.|||..
Mouse    70 EGNLIEEQALIINAHPDNIIPDTEDTEPKPMIIGTNNVFEVGCHSQAMKMGDNNVIESKAYVGRN 134

  Fly   111 VTVSSGCVVGAGIKIHGSQRLPENTIVYGEQGLQREAIDKQGSQTLQIDFLRKVLPNYHHLRK 173
            |.::|||::||...::..:.:||||::||...|:|...::...||||:|||.|:|||||||:|
Mouse   135 VILTSGCIIGACCSLNTFEAIPENTVIYGADCLRRVQTERPQPQTLQLDFLMKILPNYHHLKK 197

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DCTN6-p27	NP_609949.1	LbH_Dynactin_6	8..173	CDD:100052	84/186 (45%)
Dctn6	XP_006509157.1	LbH_Dynactin_6	10..197	CDD:100052	84/186 (45%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167837598
Domainoid	1	1.000	85	1.000	Domainoid score	I8196
eggNOG	1	0.900	-	-		E1_KOG4042
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H4792
Inparanoid	1	1.050	175	1.000	Inparanoid score	I4057
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG55965
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0005451
OrthoInspector	1	1.000	-	-		oto93583
orthoMCL	1	0.900	-	-		OOG6_104025
Panther	1	1.100	-	-	LDO	PTHR13072
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2477
SonicParanoid	1	1.000	-	-		X3876
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	15	14.790