DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment DCTN6-p27 and dnc-6

DIOPT Version :9

Sequence 1:	NP_609949.1	Gene:	DCTN6-p27 / 35195	FlyBaseID:	FBgn0086446	Length:	185	Species:	Drosophila melanogaster
Sequence 2:	NP_491116.2	Gene:	dnc-6 / 171891	WormBaseID:	WBGene00021827	Length:	180	Species:	Caenorhabditis elegans

Alignment Length:	181	Identity:	63/181 - (34%)
Similarity:	89/181 - (49%)	Gaps:	11/181 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MPSENRIKILPKAVVCEESSLRGDITFSSGCVVHPSATVIADAGPIIIGENCIIEEYATVAHRLE 65
            |...:.:.|...|:||.|:.::|::....||||||.....|..|||.:|||.|.||||.:.:..:
Worm     1 MTETSTVSIASSAIVCVEADIKGEVIIKEGCVVHPFVVFDATKGPIYVGENNIFEEYAVIRNNSD 65

  Fly    66 PGAVWDVNNILSIGTHNVFEVGCQVEAAKIGDKNVFESKCYVGPGVTVSSGCVVGAGIKIHGSQR 130
                   ...:.||..|:|:|..:..|..:|.:||......:..|.:||..|.|||...:...|.
Worm    66 -------GQPMIIGDWNIFQVHSKSSAKYVGSRNVIGVHAVLEDGCSVSDDCSVGAKCTVFSHQN 123

  Fly   131 LPENTIVYGEQGLQREAIDKQGSQTLQIDFLRKVLPNYHHLRKPNYDPKKA 181
            |..:..||....|.|.......:...||:||||:||:||||    |..|||
Worm   124 LEPSVSVYAATNLSRTTKTPNMTSPHQIEFLRKILPSYHHL----YGKKKA 170

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DCTN6-p27	NP_609949.1	LbH_Dynactin_6	8..173	CDD:100052	58/164 (35%)
dnc-6	NP_491116.2	LbH_Dynactin_6	8..166	CDD:100052	58/168 (35%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160159521
Domainoid	1	1.000	62	1.000	Domainoid score	I6910
eggNOG	1	0.900	-	-		E1_KOG4042
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H4792
Inparanoid	1	1.050	111	1.000	Inparanoid score	I3441
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG55965
OrthoDB	1	1.010	-	-		D1278795at2759
OrthoFinder	1	1.000	-	-		FOG0005451
OrthoInspector	1	1.000	-	-		oto17742
orthoMCL	1	0.900	-	-		OOG6_104025
Panther	1	1.100	-	-	LDO	PTHR13072
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2477
SonicParanoid	1	1.000	-	-		X3876
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	15	14.840