Protein Alignment AsnRS and DED81

DIOPT Version :10

• Sequence 1: NP_609948.1
• Gene: AsnRS / 35194
• FlyBaseID: FBgn0086443
• Length: 558
• Species: Drosophila melanogaster
• Sequence 2: NP_011883.1
• Gene: DED81 / 856412
• SGDID: S000001061
• Length: 554
• Species: Saccharomyces cerevisiae
• Alignment Length: 571
• Identity: 296/571 - (51%)
• Similarity: 386/571 - (67%)
• Gaps: 40/571 - (7%)

  Fly    11 LGAIFTSEKKGSDE-SGDGSESKPFKTILQAMRHAGKEPFPTIYVDTKDPNAAEP---------- 64
            :.:::..|..|.|| :..||:..||||           |...::...:..:|.||
Yeast     1 MSSLYIKEATGVDELTTAGSQDHPFKT-----------PAYALFASQQKSDATEPKLFVFKTEDN 54

  Fly    65 -YEPAAKSQLKK-------IQKLFVRESHKNADKLQREAEDAEKRQQNLEDARKVKISEDPSLPV 121
             |:..:.|.|||       ::|..|::..:...|.|:|||:|.|:.    .|..:.|.||.|||.
Yeast    55 EYQEISASALKKARKGCDGLKKKAVKQKEQELKKQQKEAENAAKQL----SALNITIKEDESLPA 115

  Fly   122 ARKIRIYEGTANRDSRVKVYGWVHRLRRQGKSLIFITLRDGTGFLQCVLNDQLCQTYDALTLSTE 186
            |.|.|||:..:....||||.||:||| |..|.:||:.||||:||:||||:..|......|.|:.|
Yeast   116 AIKTRIYDSYSKVGQRVKVSGWIHRL-RSNKKVIFVVLRDGSGFIQCVLSGDLALAQQTLDLTLE 179

  Fly   187 SSVVLFGTLKLVPEGKTAPGGHELNVDYWELIGLAPPGGADAILN---EEAQPDVQLDNRHIMIR 248
            |:|.|:||:..:|||||||||.||||||:|::||| |||.|:..|   |.:.|.:.||.||:.:|
Yeast   180 STVTLYGTIVKLPEGKTAPGGVELNVDYYEVVGLA-PGGEDSFTNKIAEGSDPSLLLDQRHLALR 243

  Fly   249 GENTSKVLKMRSVVTQAFRGHYEARGYNEVTPPTLVQTQVEGGSTLFKLKYFGEEAYLTQSSQLY 313
            |:..|.|:|:|:.:.::.|..|:.....|||||.:|||||||||||||:.|:|||||||||||||
Yeast   244 GDALSAVMKVRAALLKSVRRVYDEEHLTEVTPPCMVQTQVEGGSTLFKMNYYGEEAYLTQSSQLY 308

  Fly   314 LETCLPALGDVFTISQSYRAEQSRTRRHLAEYTHVEAECPFLTFDDLLDRLEDLVCDVVDRVLKS 378
            |||||.:||||:||.:|:|||:|.|||||:||||:|||..||||||||..:|.|:...|..||:.
Yeast   309 LETCLASLGDVYTIQESFRAEKSHTRRHLSEYTHIEAELAFLTFDDLLQHIETLIVKSVQYVLED 373

  Fly   379 P-WGYLVKELNPDFKPPQKPFRRMNYEDAIKWLKENNVTKDDGTFYEFGEDIPEAPERKMTDTIN 442
            | .|.|||:|||:||.|:.||.|:.|:|||.||.|:::..::|..::||:||.||.||||||||.
Yeast   374 PIAGPLVKQLNPNFKAPKAPFMRLQYKDAITWLNEHDIKNEEGEDFKFGDDIAEAAERKMTDTIG 438

  Fly   443 EPIMLCRFPAEIKSFYMQRCKEDQRLTESVDVLLPNVGEIVGGSMRIYDSEELLKGYKREGIDPQ 507
            .||.|.|||.|||||||:||.:|.|:|||||||:||||||.||||||.|.:||:.|:||||||..
Yeast   439 VPIFLTRFPVEIKSFYMKRCSDDPRVTESVDVLMPNVGEITGGSMRIDDMDELMAGFKREGIDTD 503

  Fly   508 PYYWYTDQRVYGTMPHGGYGLGLERFLCWLLNRYHIREVCLYPRFLDRCRP 558
            .|||:.|||.|||.||||||:|.||.|.||.:|:.:|:..|||||..||:|
Yeast   504 AYYWFIDQRKYGTCPHGGYGIGTERILAWLCDRFTVRDCSLYPRFSGRCKP 554

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AsnRS	NP_609948.1	AsnS	135..558	CDD:439788	255/426 (60%)
DED81	NP_011883.1	asnS	114..554	CDD:273086	261/441 (59%)