Protein Alignment AsnRS and Nars1

DIOPT Version :10

• Sequence 1: NP_609948.1
• Gene: AsnRS / 35194
• FlyBaseID: FBgn0086443
• Length: 558
• Species: Drosophila melanogaster
• Sequence 2: NP_001363950.1
• Gene: Nars1 / 70223
• MGIID: 1917473
• Length: 549
• Species: Mus musculus
• Alignment Length: 550
• Identity: 390/550 - (70%)
• Similarity: 468/550 - (85%)
• Gaps: 1/550 - (0%)

  Fly     9 LTLGAIFTSEKKGSDESGDGSESKPFKTILQAMRHAGKEPFPTIYVDTKDPNAAEPYEPAAKSQL 73
            :.|..::.|:::|:|.:|||::.|||||.|:|:...|||||||||||::..|.. .::..:|||:
Mouse     1 MVLAELYVSDREGNDATGDGTKEKPFKTGLKALMTVGKEPFPTIYVDSQKENEV-GWDVISKSQM 64

  Fly    74 KKIQKLFVRESHKNADKLQREAEDAEKRQQNLEDARKVKISEDPSLPVARKIRIYEGTANRDSRV 138
            |.|:|::.||..||..:.::||||..:|::|||:|:|:.|..|||||....::|......|..||
Mouse    65 KNIKKMWHREQMKNDSREKKEAEDNLRREKNLEEAKKIIIKNDPSLPEPACVKISALEGYRGQRV 129

  Fly   139 KVYGWVHRLRRQGKSLIFITLRDGTGFLQCVLNDQLCQTYDALTLSTESSVVLFGTLKLVPEGKT 203
            ||:|||||||||||:|:|:.||||||:|||||:|.|||.|:.:.|||||||.::|||.|.|:||.
Mouse   130 KVFGWVHRLRRQGKNLMFLVLRDGTGYLQCVLSDDLCQCYNGVVLSTESSVAVYGTLNLTPKGKQ 194

  Fly   204 APGGHELNVDYWELIGLAPPGGADAILNEEAQPDVQLDNRHIMIRGENTSKVLKMRSVVTQAFRG 268
            |||||||:.|:|||:||||.||||.::|||:..||||:|||:||||||.||:||.||::|:.||.
Mouse   195 APGGHELSCDFWELVGLAPAGGADNLINEESDVDVQLNNRHMMIRGENMSKILKARSMITRCFRD 259

  Fly   269 HYEARGYNEVTPPTLVQTQVEGGSTLFKLKYFGEEAYLTQSSQLYLETCLPALGDVFTISQSYRA 333
            |:..|||.|||.|||||||||||:|||||.||||||:||||||||||||||||||||.|:|||||
Mouse   260 HFFDRGYCEVTTPTLVQTQVEGGATLFKLDYFGEEAFLTQSSQLYLETCLPALGDVFCIAQSYRA 324

  Fly   334 EQSRTRRHLAEYTHVEAECPFLTFDDLLDRLEDLVCDVVDRVLKSPWGYLVKELNPDFKPPQKPF 398
            |||||||||||:||||||||||||:|||:|||||||||||||||||...:|.||||:||||::||
Mouse   325 EQSRTRRHLAEFTHVEAECPFLTFEDLLNRLEDLVCDVVDRVLKSPVASIVYELNPNFKPPKRPF 389

  Fly   399 RRMNYEDAIKWLKENNVTKDDGTFYEFGEDIPEAPERKMTDTINEPIMLCRFPAEIKSFYMQRCK 463
            |||||.|||:||||::|.|:||||||||:||||||||.|||||||||:|||||.||||||||||.
Mouse   390 RRMNYSDAIEWLKEHDVKKEDGTFYEFGDDIPEAPERLMTDTINEPILLCRFPVEIKSFYMQRCP 454

  Fly   464 EDQRLTESVDVLLPNVGEIVGGSMRIYDSEELLKGYKREGIDPQPYYWYTDQRVYGTMPHGGYGL 528
            ||.|||||||||:||||||||||||.:||||:|:|||||||||.|||||||||.|||.|||||||
Mouse   455 EDPRLTESVDVLMPNVGEIVGGSMRSWDSEEILEGYKREGIDPAPYYWYTDQRKYGTCPHGGYGL 519

  Fly   529 GLERFLCWLLNRYHIREVCLYPRFLDRCRP 558
            ||||||.|:|||||||:||||||||.||||
Mouse   520 GLERFLSWILNRYHIRDVCLYPRFLQRCRP 549

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AsnRS	NP_609948.1	AsnS	135..558	CDD:439788	334/422 (79%)
Nars1	NP_001363950.1	AsnRS_cyto_like_N	128..210	CDD:239818	58/81 (72%)
		AsxRS_core	226..545	CDD:238399	262/318 (82%)