Protein Alignment AsnRS and dars1

DIOPT Version :10

• Sequence 1: NP_609948.1
• Gene: AsnRS / 35194
• FlyBaseID: FBgn0086443
• Length: 558
• Species: Drosophila melanogaster
• Sequence 2: NP_001071079.1
• Gene: dars1 / 324025
• ZFINID: ZDB-GENE-061110-135
• Length: 531
• Species: Danio rerio
• Alignment Length: 537
• Identity: 138/537 - (25%)
• Similarity: 248/537 - (46%)
• Gaps: 58/537 - (10%)

  Fly    63 EPYEPAAKSQLKKIQKLFVRESHKNADKLQREAEDAEKRQQNLE-DARKVKISEDPSLPVARK-- 124
            |..:..:|..|||.||    |:.|.|.|.:::|:.|.::|:..| |..|.:....|.:...:|
Zfish    12 EEQQAQSKKALKKQQK----EAEKAAKKAEKQAKLASEQQETEEDDFAKDRYGICPMVQSQQKLD 72

  Fly   125 ---IRIYEGTANR-DSRVKVYGWVHRLRRQGKSLIFITLRDGTGFLQCVL------NDQLCQTYD 179
               :|:.:.|..: :.::.|...:|..|.:||. .|:.||.....:|.:|      :.|:.:.
Zfish    73 RALVRVQDLTLEKAEQQIWVRARIHTSRAKGKQ-CFLVLRHQQFTVQALLAVGDRASKQMVKF-- 134

  Fly   180 ALTLSTESSVVLFGTLKLVPE--GKTAPGGHELNVDYWELI-------------GLAPPGGADAI 229
            |..::.||.:.:...:|.|.:  ...:....||:|:...:|             .:.|.|..|..
Zfish   135 AANITKESIIDVEAVVKKVEQKIESCSQQDVELHVERIFVISQSEARLPLQLEDAVRPEGEGDEE 199

  Fly   230 LNEEAQPDVQLDNRHIMIRGENTSKVLKMRSVVTQAFRGHYEARGYNEVTPPTLVQTQVEGGSTL 294
            .......|.:||||.|.:|...:..:.:::|.|.|.||.....:|:.|:..|.::....|||:.:
Zfish   200 GRATVNQDTRLDNRVIDLRTTTSQAIFRLQSGVCQLFRDTLINKGFVEIQTPKIISAASEGGANV 264

  Fly   295 FKLKYFGEEAYLTQSSQLYLETCLPALGD-VFTISQSYRAEQSRTRRHLAEYTHVEAECPF-LTF 357
            |.:.||...|||.||.|||.:.|:.|..| ||.:...:|||.|.|.|||.|:..::.|..| ..:
Zfish   265 FTVSYFKTSAYLAQSPQLYKQMCICADFDKVFCVGPVFRAEDSNTHRHLTEFVGLDIEMAFSYHY 329

  Fly   358 DDLLDRLEDLVCDVVDRVLKSPWGYLVKELNPDFKPPQKPFR------RMNYEDAIKWLKENNVT 416
            .:::|.:.|.:..:. :.|:..:...::.:|..:  |.:||:      |:.|::.:..|:...|.
Zfish   330 HEVIDSITDTMVQIF-KGLRDRFQTEIQTVNKQY--PSEPFKFLEPTLRLEYKEGLAMLRAAGVE 391

  Fly   417 KDDGTFYEFGEDIPEAPERKMTDTINEP-----IMLCRFPAEIKSFYMQRCKEDQRLTESVDVLL 476
            ..|      .||:....|:.:...:.|.     .:|.::|..::.||......:.:.:.|.|:.:
Zfish   392 MGD------EEDLSTPNEKLLGRLVKEKYDTDFYVLDKYPLAVRPFYTMPDPNNPKYSNSYDMFM 450

  Fly   477 PNVGEIVGGSMRIYDSEELLKGYKREGIDPQPYYWYTDQRVYGTMPHGGYGLGLERFLCWLLNRY 541
            .. .||:.|:.||:|::.|.:......||.:....|.|...||..||.|.|:||||.....|..:
Zfish   451 RG-EEILSGAQRIHDAQLLTERAMHHNIDLEKIKAYIDSFRYGAPPHAGGGIGLERVTMLYLGLH 514

  Fly   542 HIREVCLYPRFLDRCRP 558
            ::|:..::||...|..|
Zfish   515 NVRQTSMFPRDPKRLTP 531

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AsnRS	NP_609948.1	AsnS	135..558	CDD:439788	116/456 (25%)
dars1	NP_001071079.1	PLN02850	11..531	CDD:215456	137/535 (26%)