DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment AsnRS and slm5

DIOPT Version :9

Sequence 1:	NP_001260561.1	Gene:	AsnRS / 35194	FlyBaseID:	FBgn0086443	Length:	558	Species:	Drosophila melanogaster
Sequence 2:	NP_595079.1	Gene:	slm5 / 2539632	PomBaseID:	SPBC1198.10c	Length:	441	Species:	Schizosaccharomyces pombe

Alignment Length:	454	Identity:	124/454 - (27%)
Similarity:	213/454 - (46%)	Gaps:	82/454 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   138 VKVYGWVHRLRRQGKSLIFITLRDGTGFLQCVLNDQLCQTYDALTLSTESSVVLFGTLKLVPEGK 202
            :.:.|||..:|:. |::.|..:.|||           ||....:..|.|.|..|.....:..||:
pombe    23 ISINGWVRSIRKL-KNVCFAMVSDGT-----------CQQALQVVTSPEQSKKLSYGASVNIEGQ 75

  Fly   203 TAPGGH-ELNVDYWELIGLAPPGGADAI-----LNEEAQP--------DVQLDNRHIMIRGENTS 253
            .|...: :|.:..:||:       |:.|     :|::..|        ::.....|:.:|.....
pombe    76 LAVSKNAKLGLQQYELL-------AEKIKIYGQINDDNYPIQKKHLTTEMLRQIPHLRLRTAKQG 133

  Fly   254 KVLKMRSVVTQAFRGHYEARGYNEVTPPTLVQTQVEGGSTLFKL-----------------KYFG 301
            ::.::||...:|.|..:.::.:.|..||.:..:..||...:|.|                 .:|.
pombe   134 EIFRLRSDSLKALRQFFSSKDFTETNPPIITSSDCEGAGEVFTLTPQETHKNKSFERDDQKHFFD 198

  Fly   302 EEAYLTQSSQLYLETCLPALGDVFTISQSYRAEQSRTRRHLAEYTHVEAECPFLT-FDDLLDRLE 365
            ..|:||.|:||:||.....|..|:|||.::|||||.|.|||||:..:|||..|:| ...|...:|
pombe   199 RPAFLTVSTQLHLEALALGLSRVYTISPAFRAEQSHTSRHLAEFWMLEAEVAFMTSLSQLTSLME 263

  Fly   366 DLVCDVVDRVL-----KSPWGYLVKELNPDFKPPQKPFRRMNYEDAIKWLKENNVTKDDGTF-YE 424
            |::...::.::     :..|..|:           ||::.|.|.:||   :|.:..|....: .:
pombe   264 DMIKYTLNSLMEQNYHRDHWDQLL-----------KPWKCMTYSEAI---EELSAVKKTWKYPPK 314

  Fly   425 FGEDIPEAPERKMTDTINE-PIMLCRFPAEIKSFYMQRCKEDQRLTESVDVLLPNVGEIVGGSMR 488
            :|.|:....|:.:.:.::: |:.:..:|.:||.|||:....|  ...:||:|:|.|||:.|||:|
pombe   315 WGNDLSSEHEKYLCEILHKTPVFVTDYPQKIKPFYMKSSGPD--TVAAVDLLVPQVGELAGGSLR 377

  Fly   489 IYDSEELLKGYKREGIDPQPYYWYTDQRVYGTMPHGGYGLGLERFLCWLL-NRYHIREVCLYPR 551
                ::.|..||..   |....||.|...|...||||:|||:||.:.:|. ...:::|...:||
pombe   378 ----KDHLDEYKTY---PPELQWYLDLMKYSNAPHGGFGLGIERLIAFLEGENTNVKETIPFPR 434

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
AsnRS	NP_001260561.1	AsnS	122..558	CDD:223096	124/454 (27%)
		AsnRS_cyto_like_N	137..219	CDD:239818	21/81 (26%)
		AsxRS_core	233..552	CDD:238399	100/353 (28%)
slm5	NP_595079.1	asnC	9..439	CDD:235176	124/454 (27%)
		EcAsnRS_like_N	23..101	CDD:239813	23/96 (24%)
		AsxRS_core	113..434	CDD:238399	97/343 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0017
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810