Protein Alignment AsnRS and Dars1

DIOPT Version :10

• Sequence 1: NP_609948.1
• Gene: AsnRS / 35194
• FlyBaseID: FBgn0086443
• Length: 558
• Species: Drosophila melanogaster
• Sequence 2: NP_803228.2
• Gene: Dars1 / 226414
• MGIID: 2442544
• Length: 501
• Species: Mus musculus
• Alignment Length: 518
• Identity: 137/518 - (26%)
• Similarity: 238/518 - (45%)
• Gaps: 66/518 - (12%)

  Fly    84 SHKNADKLQRE----AEDAEKRQQNLEDARKVKISEDPSLPVARKIRIYEGTANR-DSRVKVYGW 143
            |.|..:| .||    |||..|.:..:  :..::..|.|...:   :|:.:.|..: |..|.|...
Mouse     7 SRKGQEK-PREIVDAAEDYAKERYGI--SSMIQSQEKPDRVL---VRVKDLTVQKADDVVWVRAR 65

  Fly   144 VHRLRRQGKSLIFITLRDGTGFLQCVL------NDQLCQTYDALTLSTESSVVLFGTLKLVPE-- 200
            ||..|.:||. .|:.||.....:|.::      :.|:.:.  |..::.||.:.:.|.::.|.:
Mouse    66 VHTSRAKGKQ-CFLVLRQQQFNVQALVAVGDHASKQMVKF--AANINKESIIDVEGVVRKVNQKI 127

  Fly   201 GKTAPGGHELNVDYWELIGLAPP---------------GGAD--AILNEEAQPDVQLDNRHIMIR 248
            |.......||:|....:|.||.|               |..|  |.:|:    |.:||||.|.:|
Mouse   128 GSCTQQDVELHVQKIYVISLAEPRLPLQLDDAIRPEVEGEEDGRATVNQ----DTRLDNRVIDLR 188

  Fly   249 GENTSKVLKMRSVVTQAFRGHYEARGYNEVTPPTLVQTQVEGGSTLFKLKYFGEEAYLTQSSQLY 313
            ...:..:.:::|.:...||.....:|:.|:..|.::....|||:.:|.:.||...|||.||.|||
Mouse   189 TSTSQAIFRLQSGICHLFRETLINKGFVEIQTPKIISAASEGGANVFTVSYFKNNAYLAQSPQLY 253

  Fly   314 LETCLPA-LGDVFTISQSYRAEQSRTRRHLAEYTHVEAECPF-LTFDDLLDRLEDLVCDVVDRVL 376
            .:.|:.| ...||.|...:|||.|.|.|||.|:..::.|..| ..:.::::.:.|.:..:. :.|
Mouse   254 KQMCICADFEKVFCIGPVFRAEDSNTHRHLTEFVGLDIEMAFNYHYHEVVEEIADTLVQIF-KGL 317

  Fly   377 KSPWGYLVKELNPDFKPPQKPFR------RMNYEDAIKWLKENNVTKDDGTFYEFGEDIPEAPER 435
            :..:...::.::..|  |.:||:      |:.|.:|:..|:|..|..||      .||:....|:
Mouse   318 QERFQTEIQTVSKQF--PCEPFKFLEPTLRLEYCEALAMLREAGVEMDD------EEDLSTPNEK 374

  Fly   436 KMTDTINEP-----IMLCRFPAEIKSFYMQRCKEDQRLTESVDVLLPNVGEIVGGSMRIYDSEEL 495
            .:...:.|.     .:|.::|..::.||......:.:.:.|.|:.:.. .||:.|:.||:|.:.|
Mouse   375 LLGRLVKEKYDTDFYVLDKYPLAVRPFYTMPDPRNPKQSNSYDMFMRG-EEILSGAQRIHDPQLL 438

  Fly   496 LKGYKREGIDPQPYYWYTDQRVYGTMPHGGYGLGLERFLCWLLNRYHIREVCLYPRFLDRCRP 558
            .:.....|||.:....|.|...:|..||.|.|:||||.....|..:::|:..::||...|..|
Mouse   439 TERALHHGIDLEKIKAYIDSFRFGAPPHAGGGIGLERVTMLFLGLHNVRQTSMFPRDPKRLTP 501

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AsnRS	NP_609948.1	AsnS	135..558	CDD:439788	123/460 (27%)
Dars1	NP_803228.2	PLN02850	20..501	CDD:215456	131/502 (26%)
		Aspartate. /evidence=ECO:0000250	251..254		2/2 (100%)