Protein Alignment AsnRS and nars-1

DIOPT Version :10

• Sequence 1: NP_609948.1
• Gene: AsnRS / 35194
• FlyBaseID: FBgn0086443
• Length: 558
• Species: Drosophila melanogaster
• Sequence 2: NP_001021405.1
• Gene: nars-1 / 172442
• WormBaseID: WBGene00003815
• Length: 545
• Species: Caenorhabditis elegans
• Alignment Length: 552
• Identity: 317/552 - (57%)
• Similarity: 410/552 - (74%)
• Gaps: 11/552 - (1%)

  Fly    11 LGAIFTSEKKGSDESGDGSESKPFKTILQAM---RHAGKEPFPTIYVDTKDPNAAEPYEPAAKSQ 72
            :..::.....|||:. .|:|::|..|::|||   :::|:      ::..|.....|.:|||||:.
 Worm     1 MSKLYIDTDAGSDQH-PGTEAQPLATLVQAMLISKNSGE------FLMKKKSEEGESWEPAAKAA 58

  Fly    73 LKKIQKLFVRESHKNADKLQREAEDAEKRQQNLEDARKVKISEDPSLPVARKIRIYEGTANRDSR 137
            :||..|.:..|..|......||.|..|.:...||:|:|:..|.|.|||.|:.|:|.|...:||.|
 Worm    59 IKKAVKKYEAEVKKLEKAGCREKEAEEAQHAALEEAKKITFSLDKSLPEAKVIKIGESVQHRDQR 123

  Fly   138 VKVYGWVHRLRRQGKSLIFITLRDGTGFLQCVLNDQLCQTYDALTLSTESSVVLFGTLKLVPEGK 202
            |.:..||||||||||||:|:.||||.|||||||||:|||:|||:|||||:||.::|.:|.:|:||
 Worm   124 VSIKAWVHRLRRQGKSLMFLVLRDGYGFLQCVLNDKLCQSYDAVTLSTETSVQVYGIIKALPDGK 188

  Fly   203 TAPGGHELNVDYWELIGLAPPGGADAILNEEAQPDVQLDNRHIMIRGENTSKVLKMRSVVTQAFR 267
            :||.||||.|||||:||.||.||.|.:|||.|..||.|||||::|||||.|::|::|:..|:|.|
 Worm   189 SAPDGHELTVDYWEVIGKAPAGGIDNVLNESAGVDVMLDNRHLVIRGENASRILRIRAAATRAMR 253

  Fly   268 GHYEARGYNEVTPPTLVQTQVEGGSTLFKLKYFGEEAYLTQSSQLYLETCLPALGDVFTISQSYR 332
            .|:.|.||.||.||||||||||||||||.|.|:||.||||||||||||||..|||||:.||||||
 Worm   254 DHFFAAGYTEVAPPTLVQTQVEGGSTLFGLDYYGEPAYLTQSSQLYLETCNAALGDVYCISQSYR 318

  Fly   333 AEQSRTRRHLAEYTHVEAECPFLTFDDLLDRLEDLVCDVVDRVLKSP-WGYLVKELNPDFKPPQK 396
            ||:|||||||:||.||||||.|:|||.|:||:|.||||.|||:|..| ...|::.:||.:|.|.:
 Worm   319 AEKSRTRRHLSEYQHVEAECAFITFDQLMDRIEALVCDTVDRLLADPVTKSLIEFVNPGYKAPAR 383

  Fly   397 PFRRMNYEDAIKWLKENNVTKDDGTFYEFGEDIPEAPERKMTDTINEPIMLCRFPAEIKSFYMQR 461
            ||:||.|::||:||::|:|..:.|..:.:||||.||.||:|||||..||:|.|||..||:|||.|
 Worm   384 PFKRMPYKEAIEWLQKNDVRNEMGEKFVYGEDIAEAAERRMTDTIGVPILLNRFPHGIKAFYMPR 448

  Fly   462 CKEDQRLTESVDVLLPNVGEIVGGSMRIYDSEELLKGYKREGIDPQPYYWYTDQRVYGTMPHGGY 526
            |.:|..||||||:|:|.|||||||||||:..::||..:::.|:|.:.||||.|||.||::|||||
 Worm   449 CADDNELTESVDLLMPGVGEIVGGSMRIWKEDQLLAAFEKGGLDSKNYYWYMDQRKYGSVPHGGY 513

  Fly   527 GLGLERFLCWLLNRYHIREVCLYPRFLDRCRP 558
            |||||||:|||.:..|||:|||||||:.||.|
 Worm   514 GLGLERFICWLTDTNHIRDVCLYPRFVGRCAP 545

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AsnRS	NP_609948.1	AsnS	135..558	CDD:439788	275/423 (65%)
nars-1	NP_001021405.1	AsnRS_cyto_like_N	123..206	CDD:239818	58/82 (71%)
		AsxRS_core	220..541	CDD:238399	205/320 (64%)