Protein Alignment l(2)37Cd and TFC1

DIOPT Version :10

• Sequence 1: NP_609947.1
• Gene: l(2)37Cd / 35193
• FlyBaseID: FBgn0086445
• Length: 480
• Species: Drosophila melanogaster
• Sequence 2: NP_009681.3
• Gene: TFC1 / 852421
• SGDID: S000000327
• Length: 649
• Species: Saccharomyces cerevisiae
• Alignment Length: 625
• Identity: 124/625 - (19%)
• Similarity: 213/625 - (34%)
• Gaps: 213/625 - (34%)

  Fly     2 SRQLSFNPQKEYELIEYPGRVVNPDRMIATLGGIINVSKVLGDEVKRLALHFHPENPYNKPTF-G 65
            |.:|..|...::..|:         :.|...|||..|.:...:       |...|:.:....: .
Yeast    38 SLELPLNVSTKHSSIQ---------KAIKMCGGIEKVKEAFKE-------HGPIESQHGLQLYLN 86

  Fly    66 DCTDKTG---------------------VLLSIT------------VRRHKKDKQRPPEYFVRVL 97
            |.||..|                     |:|.:|            |:...|..:...:..|..:
Yeast    87 DDTDSDGSKSYFNEHPVIGKRVPFRDESVILKVTMPKGTLSKNNNSVKDSIKSLKDSNKLRVTPV 151

  Fly    98 GHCSRSFTFETLCDFQYLPLWSTPKSDNANAAQELTYALDQLK-----------PKN-------- 143
            .....:..|..:.|||.       |.||..:|:|...:...|:           |.|
Yeast   152 SIVDNTIKFREMSDFQI-------KLDNVPSAREFKSSFGSLEWNNFKSFVNSVPDNDSQPQENI 209

  Fly   144 ------------TTDLDYFKRRHSQLLALPELFTHVDTVYAGTYRIDP----SEDGQHEVLGVQS 192
                        :||..........::..|.|:         .|:.:|    .::|..||.|...
Yeast   210 GNLILDRSVKIPSTDFQLPPPPKLSMVGFPLLY---------KYKANPFAKKKKNGVTEVKGTYI 265

  Fly   193 KSSYDNQGVVSFNMVDS--FPTQADSQNL------KRLKVK---------YVS-DEQLALVKKLF 239
            |    |..:...::.|.  .|:||..|.|      |:.||.         |.| :|.|.::::||
Yeast   266 K----NYQLFVHDLSDKTVIPSQAHEQVLYDFEVAKKTKVYPGTKSDSKFYESLEECLKILRELF 326

  Fly   240 DDCPIWTRIALQYESGLTNDK----LKCITPSLAFYFSNGPWRTLYVRFGYDPRKDFNSRYYQTF 300
            ...|||.:   ::..|:...|    :|.....:::.|:.||||..|::||.|||.......|||.
Yeast   327 ARRPIWVK---RHLDGIVPKKIHHTMKIALALISYRFTMGPWRNTYIKFGIDPRSSVEYAQYQTE 388

  Fly   301 DFRLRFSTGLSEFVYAKKFVKQRRAANAPFAPIEDRVSDLVQDIDYPY-FDEHKLP--RSRQCML 362
            .|:      :...:.:...||:    |.|..|.....||....||..: ||..::|  ...|..|
Yeast   389 YFK------IERKLLSSPIVKK----NVPKPPPLVFESDTPGGIDSRFKFDGKRIPWYLMLQIDL 443

  Fly   363 RYCDVRMTRI---QEMLEKIPTPLTGAVCNERTGWLPPGFDAQVRQIVCASISELLRNHYR---- 420
            ...:..:..:   .|.|:|         .||.|||.......::|:||...:..:::.:|.
Yeast   444 LIGEPNIAEVFHNVEYLDK---------ANELTGWFKELDLVKIRRIVKYELGCMVQGNYEYNKY 499

  Fly   421 -----------KENLTAE---------------------VEAVTQ----ADEEDE---------- 439
                       ||::..|                     ::|.:|    |.|||:
Yeast   500 KLKYFKTMLFVKESMVPENKNSEEGMGVNTNKDADGDINMDAGSQMSSNAIEEDKGIAAGDDFDD 564

  Fly   440 -----DEAEDEETQEEDMELDETQAMGNSEQFVDNDIEQL 474
                 :|.:|...:.|:|:.|:...:..|   :|:|::.:
Yeast   565 NGAITEEPDDAALENEEMDTDQNLKVPAS---IDDDVDDV 601

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
l(2)37Cd	NP_609947.1	Tau95_N	16..115	CDD:465457	22/132 (17%)
		Tau95	160..303	CDD:462865	45/168 (27%)
TFC1	NP_009681.3	Tau95_N	37..167	CDD:465457	23/144 (16%)
		Tau95	227..391	CDD:462865	45/179 (25%)