DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment l(2)37Cd and gtf3c5

DIOPT Version :9

Sequence 1:	NP_609947.1	Gene:	l(2)37Cd / 35193	FlyBaseID:	FBgn0086445	Length:	480	Species:	Drosophila melanogaster
Sequence 2:	XP_002936239.2	Gene:	gtf3c5 / 100492614	XenbaseID:	XB-GENE-1012275	Length:	518	Species:	Xenopus tropicalis

Alignment Length:	505	Identity:	140/505 - (27%)
Similarity:	224/505 - (44%)	Gaps:	83/505 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 IEYPGRVVNPDRMIATLGGIINVSKVLGDEVKRLALHFHPENPYNKPTFGDCTDKTGVLLSI--T 78
            :||||.|.:..:|:.||||...|||...|..|||.|:|.|.:||..|..|:....|.::|.:  .
Frog    25 VEYPGLVRDVGKMLRTLGGEEGVSKTYADPSKRLELYFRPNDPYCHPLCGNRFPTTTMILRVKKK 89

  Fly    79 VRRHKKDKQRPPE------YFVRVLGHCSRSFTFETLCDFQYLPLWSTPKSDNANAAQELTYALD 137
            |||.|......||      ..:.::|.....:.|:.:.|||||.....|..:..:...::...
Frog    90 VRRKKAPDPGAPEPTEEGKISLEIIGVVGTVYKFQGMSDFQYLAFKQDPDGNRTSLYDKVLLC-- 152

  Fly   138 QLKPKNTTDLDYFKRRHSQLLAL---PELFTHVDTVYAGTYRIDPS--------EDGQHEVLGVQ 191
              ||:..   |:|    :|.:||   |.:|:.:|......||.|.:        :.....::|:.
Frog   153 --KPEKE---DFF----NQEIALHIPPPIFSRLDNCVDYFYRPDVNHREGYRLPQVSNDNLIGLS 208

  Fly   192 SKSSYDNQGVVSFN--MVDSFPTQADSQNLKRLKVKYVSDEQLALVKKLFDDCPIWTRIALQYES 254
            ......|...|||.  .:.:.|.|...:|..::....:..:....:::||.:.|||:|.|::...
Frog   209 RARRPHNAIFVSFEEAEIPNEPLQPAVKNWTKMCTNPMDKQAEEEMRQLFTNRPIWSRNAIKANI 273

  Fly   255 GLTNDKLKCITPSLAFYFSNGPWRTLYVRFGYDPRKDFNSRYYQTFDFRLRFSTGLSEFVYAKKF 319
            .:..||||.:.|.:|:|...||||:|:|||||||||:..::.||..|||:|...   ::.||...
Frog   274 SVHPDKLKLLLPIVAYYMLTGPWRSLWVRFGYDPRKNPEAKIYQVLDFRIRCGV---KYGYAPND 335

  Fly   320 --VKQRRAA---NAPF-----APIEDRVSDLVQDIDYP----------------------YFDEH 352
              ||.:|:.   :.|.     ||....|.||.|.:..|                      .|.|.
Frog   336 MPVKAKRSTYNYSLPITLKKPAPQVVSVQDLKQGLAAPSSNTPGGTKPGFNKYKLKESIYIFQEG 400

  Fly   353 KLPRSRQCMLRYCDVRMTRIQEMLEKIPTPLTGAVCNERTGWLPPGFDAQVRQIVCASISELLRN 417
            .||..||...:.||:.:..::::::.  .....|.|.||.||..|....::|..:...|.:::|:
Frog   401 NLPPYRQMFYQLCDLNVDSLRDIIQM--NEGAEAECTERDGWCLPKTSEKLRDAMSLMIKQIIRS 463

  Fly   418 H------------YRKENLTAEVEAVTQADEEDEDEAEDEETQEEDMELD 455
            .            ..||.||  .|:..:.|||:|:|....|..|.:||.:
Frog   464 KRPSLFSEPSTSTSNKEQLT--YESGEEEDEEEEEEFHPSEGSENEMETE 511

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
l(2)37Cd	NP_609947.1	Tau95	13..303	CDD:286777	92/307 (30%)
gtf3c5	XP_002936239.2	Tau95_N	25..132	CDD:375251	37/106 (35%)
gtf3c5	XP_002936239.2	Tau95	168..322	CDD:370643	45/153 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	81	1.000	Domainoid score	I8450
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H40806
Inparanoid	1	1.050	165	1.000	Inparanoid score	I4072
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1111142at2759
OrthoFinder	1	1.000	-	-		FOG0003593
OrthoInspector	1	1.000	-	-		oto103225
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X2465
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	7.060