Protein Alignment l(2)37Cb and Dqx1

DIOPT Version :10

• Sequence 1: NP_609946.1
• Gene: l(2)37Cb / 35192
• FlyBaseID: FBgn0086444
• Length: 894
• Species: Drosophila melanogaster
• Sequence 2: NP_291084.1
• Gene: Dqx1 / 93838
• MGIID: 2136388
• Length: 718
• Species: Mus musculus
• Alignment Length: 668
• Identity: 229/668 - (34%)
• Similarity: 359/668 - (53%)
• Gaps: 47/668 - (7%)

  Fly   247 ETRRSLPVYP----FKEDLIAAVKEHQVLIIEGETGSGKTTQVPQYLVE----AGFTKDKKMIGC 303
            |.||:||::.    |.|.|.::  ...|:::.|:.||||:||:||:..|    .||...:  :..
Mouse    37 EQRRALPIWAARFLFLEHLESS--PTGVVLVSGDPGSGKSTQIPQWCAEFALARGFQTGQ--VTV 97

  Fly   304 TQPRRVAAMSVAARVAEEMGVKLGNEVGYSIRFEDCTSDRTILKYMTDGTLHREFLSEPDLASYS 368
            |||..:||||:|:|||:||.:.||:|:||||..||||...|:|::..|....:|..|.....::|
Mouse    98 TQPYPLAAMSLASRVADEMDLTLGHEIGYSIPQEDCTGPNTMLRFCWDRLFLQEVASTRGPGAWS 162

  Fly   369 VMIIDEAHERTLHTDILFGLVKDIARFR-----PELKLLISSATLDAEKFSAFFDDAPIFRIPGR 428
            |:|:|||.||::.:|:|.||::| .|.|     |.: ::::...|: .||.||:.::||.|:|
Mouse   163 VLILDEAQERSVASDLLQGLLRD-TRLRNLPGDPRV-VVVTDPALE-PKFQAFWGNSPIVRVP-- 222

  Fly   429 RYP---VDIFYTKAPEADYIDACCVSVLQI-HATQPLGDILVFLTGQDEIETCQEVLHDRVKRLG 489
            |.|   ..:.|......|.::|.|.:||:: ...:..||:||:|..::||..|.|.|...:..|.
Mouse   223 REPGGDPTLAYKDTVPTDLVEAACQAVLELCQQEEAPGDVLVYLPSEEEISLCCESLSGEMGTLA 287

  Fly   490 SKIRELIVIPVYANLPSDMQAKIFEPTPPNARKVILATNIAETSLTIDNIIYVIDPGFAKQNNFN 554
            .......|:|::......:|. ::|.|..:.||:::...:|:.|.::.:|.:|||.|...::.:|
Mouse   288 VPGPPPRVLPLHPGCAQAIQT-VYEDTDVSVRKIVVTHWLADFSFSLPSIQHVIDSGLELRSVYN 351

  Fly   555 SRTGMESLMVVPISKASANQRAGRAGRTAPGKCFRLYTAWAYKHELEDNTVPEIQRINLGNAVLM 619
            .|...||.::.||||..|..|..||....||.|.|||:....:.|......|::...||.:.||:
Mouse   352 PRIRAESQVLRPISKCQAEARLLRAKGFPPGSCLRLYSKSTLELEAPPLPHPKVCEENLSSLVLL 416

  Fly   620 LKALGINDLIHFDFLDPPPHETLVLALEQLYALGALNHHGELTKLGRRMAEFPVDPMMGKMLLAS 684
            |....|.:.....|||.|..|.|:.|||.|..|.|||..|||:.||..::|||:.|.:.|.||||
Mouse   417 LMRKQIAEPGECHFLDRPAPEALMRALEDLDYLAALNDDGELSDLGVILSEFPLPPELAKALLAS 481

  Fly   685 EKYKCSEEMVTIAAMLSVNSAIFYRPKDKIIHADTA--RKNFNHMHGDHLSLLQVYNQWAETDYS 747
            .::.|.:||:|:||||:.... |.||.   :.|..|  |:...|..|||.||:|||..:.::...
Mouse   482 CEFNCVDEMLTLAAMLTAAPG-FTRPP---LSAGEAALRRALEHADGDHSSLIQVYEAFVQSGAD 542

  Fly   748 TQWCYENFIQYRSMKRARDVREQLVGLMQRVEIDM----VSCLPETVNVRKAATAGYFYHVARLS 808
            ..||....:.:.|:.:||.:|.:||.||||:|:.:    ........:::||..:|||..|||.:
Mouse   543 EAWCQARGLNWESLCQARKLRAELVELMQRIELPLSQPAFGSEQNRRDLQKALLSGYFLKVARDT 607

  Fly   809 KG-GHYKTIKHNQTVMIHP-----NSSLFEELPRWVLYHELVFTSKEYMRQVIEIESKWLLEVAP 867
            .| |:|..:.|.....:.|     |.....:.|.|||||....:....:..|.||:.:.|:|:||
Mouse   608 DGTGNYLLLTHKHVAQLSPYCSYRNRRTPAQPPTWVLYHSFSISKDNCLCIVSEIQPEMLVELAP 672

  Fly   868 HYYKA----KELEDSTNK 881
            .|:.:    .|..|..|:
Mouse   673 PYFLSNLPPSESRDLLNQ 690

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
l(2)37Cb	NP_609946.1	PTZ00121	<6..267	CDD:173412	8/23 (35%)
		HrpA	251..>868	CDD:441249	221/645 (34%)
Dqx1	NP_291084.1	HrpA	41..>615	CDD:441249	206/587 (35%)
		DEAD-like_helicase_N	42..221	CDD:475120	70/185 (38%)
		DEAQ box. /evidence=ECO:0000305|PubMed:11353393	167..170		2/2 (100%)
		OB_NTP_bind	591..674	CDD:400182	27/82 (33%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	690..718		0/1 (0%)