DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment l(2)37Cb and AT3G26560

DIOPT Version :9

Sequence 1:	NP_609946.1	Gene:	l(2)37Cb / 35192	FlyBaseID:	FBgn0086444	Length:	894	Species:	Drosophila melanogaster
Sequence 2:	NP_189288.1	Gene:	AT3G26560 / 822264	AraportID:	AT3G26560	Length:	1168	Species:	Arabidopsis thaliana

Alignment Length:	1033	Identity:	433/1033 - (41%)
Similarity:	619/1033 - (59%)	Gaps:	176/1033 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 EEPDSEEESRLKDLQE--RDEFASRLKKRDD------DRTRNVVDSTG-GRRAIEEATKRLK--- 69
            |....|:.:|.:|.:|  ||....|.:.|||      ||.||..|..| .||:.....:|.:
plant   120 ERRREEDRNRDRDRRESGRDRDRDRNRDRDDRRDRHRDRERNRGDEEGEDRRSDRRHRERGRGDG 184

  Fly    70 LEHED--RDKIVPHLRLQSRRQYLEKRKD---------------DKVAELEADILDDEYLFDESV 117
            .|.||  ||:       :::.:|:|:.|.               .:|.:....:..|::...|.:
plant   185 GEGEDRRRDR-------RAKDEYVEEDKGGANEPELYQVYKGRVTRVMDAGCFVQFDKFRGKEGL 242

  Fly   118 L------TKREKEEREYKK-------QLLNIAK----------EHEKARELERIQRYNMPQDLKK 159
            :      |:|..:.:|:.|       ::::|:.          :....|:|..:::.:...|..:
plant   243 VHVSQMATRRVDKAKEFVKRDMEVYVKVISISSDKYSLSMRDVDQNTGRDLIPLRKPSDEDDSSR 307

  Fly   160 GERSEYVE--------------VDEFEKQPN-------SEQKKWEAEQLASA------RFHFGAK 197
            ...|...:              |:|.:..|:       |..::|||:||.::      .|....:
plant   308 SNPSYRTKDGQVTKTGISGIRIVEENDVAPSRRPLKKMSSPERWEAKQLIASGVLRVDEFPMYDE 372

  Fly   198 DAK--------AEEEYEL-LLDDQIDFIQALTL--------------DGSREKSSSRQPELTEK- 238
            |..        ||||.|: :.:|:..|:|..|.              :||..::::.|..||::
plant   373 DGDGMLYQEEGAEEELEIEMNEDEPAFLQGQTRYSVDMSPVKIFKNPEGSLSRAAALQSALTKER 437

  Fly   239 ----------------------------------------------------------------E 239
                                                                            :
plant   438 REMREQQQRTMLDSIPKDLNRPWEDPMPETGERHLAQELRGVGLSAYDMPEWKKDAFGKTPTFGQ 502

  Fly   240 RKRLTLDETRRSLPVYPFKEDLIAAVKEHQVLIIEGETGSGKTTQVPQYLVEAGFTKDKKMIGCT 304
            |.:|::.|.|.|||:|..|::||.||.::|||::.|||||||||||.|||.|||:| .|..||||
plant   503 RSKLSIQEQRESLPIYKLKKELIQAVHDNQVLVVIGETGSGKTTQVTQYLAEAGYT-TKGKIGCT 566

  Fly   305 QPRRVAAMSVAARVAEEMGVKLGNEVGYSIRFEDCTSDRTILKYMTDGTLHREFLSEPDLASYSV 369
            |||||||||||.|||||.|.:||.||||:|||||||...|::||||||.|.||.|.:.:|:.|||
plant   567 QPRRVAAMSVAKRVAEEFGCRLGEEVGYAIRFEDCTGPDTVIKYMTDGMLLREILIDENLSQYSV 631

  Fly   370 MIIDEAHERTLHTDILFGLVKDIARFRPELKLLISSATLDAEKFSAFFDDAPIFRIPGRRYPVDI 434
            :::|||||||:|||:||||:|.:.:.|.:|:|:::||||||||||.:|.:..||.||||.:||:|
plant   632 IMLDEAHERTIHTDVLFGLLKKLMKRRLDLRLIVTSATLDAEKFSGYFFNCNIFTIPGRTFPVEI 696

  Fly   435 FYTKAPEADYIDACCVSVLQIHATQPLGDILVFLTGQDEIETCQEVLHDRVKRLGSKIRELIVIP 499
            .|||.||.||:||..::|||||.|:|.||||||||||:||::..:.|::|:|.||..:.|||::|
plant   697 LYTKQPETDYLDAALITVLQIHLTEPEGDILVFLTGQEEIDSACQSLYERMKGLGKNVPELIILP 761

  Fly   500 VYANLPSDMQAKIFEPTPPNARKVILATNIAETSLTIDNIIYVIDPGFAKQNNFNSRTGMESLMV 564
            ||:.|||:||::||:|.||..|||::||||||.|||||.|.||:||||||||.:|.:.|:|||::
plant   762 VYSALPSEMQSRIFDPPPPGKRKVVVATNIAEASLTIDGIYYVVDPGFAKQNVYNPKQGLESLVI 826

  Fly   565 VPISKASANQRAGRAGRTAPGKCFRLYTAWAYKHELEDNTVPEIQRINLGNAVLMLKALGINDLI 629
            .|||:|||.|||||||||.||||:||||..||::|:...::|||||||||...|.:||:|||||:
plant   827 TPISQASAKQRAGRAGRTGPGKCYRLYTESAYRNEMPPTSIPEIQRINLGMTTLTMKAMGINDLL 891

  Fly   630 HFDFLDPPPHETLVLALEQLYALGALNHHGELTKLGRRMAEFPVDPMMGKMLLASEKYKCSEEMV 694
            .|||:|||..:.|:.|:||||:||||:..|.||||||:|||||::|.:.||||||....||:|::
plant   892 SFDFMDPPQPQALISAMEQLYSLGALDEEGLLTKLGRKMAEFPLEPPLSKMLLASVDLGCSDEIL 956

  Fly   695 TIAAMLSVNSAIFYRPKDKIIHADTARKNFNHMHGDHLSLLQVYNQWAETDYSTQWCYENFIQYR 759
            |:.||:...: |||||::|...||..|..|....||||:||.||..|...::|..||:|||||.|
plant   957 TMIAMIQTGN-IFYRPREKQAQADQKRAKFFQPEGDHLTLLAVYEAWKAKNFSGPWCFENFIQSR 1020

  Fly   760 SMKRARDVREQLVGLMQRVEIDMVSCLPETVNVRKAATAGYFYHVARLSKGGHYKTIKHNQTVMI 824
            |::||:|||:||:.:|.:.::|:|:.......:|||.|||:|:|.||......|:|:..||.|.|
plant  1021 SLRRAQDVRKQLLSIMDKYKLDVVTAGKNFTKIRKAITAGFFFHGARKDPQEGYRTLVENQPVYI 1085

  Fly   825 HPNSSLFEELPRWVLYHELVFTSKEYMRQVIEIESKWLLEVAPHYYKAKELEDSTNKK 882
            ||:|:||:..|.||:||:||.|:|||||:|..|:.|||:|:||.::|..:....:.:|
plant  1086 HPSSALFQRQPDWVIYHDLVMTTKEYMREVTVIDPKWLVELAPRFFKVSDPTKMSKRK 1143

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
l(2)37Cb	NP_609946.1	HrpA	222..867	CDD:224557	369/709 (52%)
		DEXDc	269..408	CDD:238005	91/138 (66%)
		HELICc	491..581	CDD:197757	58/89 (65%)
		HA2	651..735	CDD:214852	43/83 (52%)
		OB_NTP_bind	770..869	CDD:285018	47/98 (48%)
AT3G26560	NP_189288.1	GH2-like_DHX8	9..76	CDD:409668
		S1_DHX8_helicase	214..290	CDD:240189	8/75 (11%)
		HrpA	504..1129	CDD:224557	364/626 (58%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1643
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53574
OrthoDB	1	1.010	-	-		D354219at2759
OrthoFinder	1	1.000	-	-		FOG0000059
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100085
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X141
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	8	7.730