Protein Alignment l(2)37Cb and dhx35

DIOPT Version :10

• Sequence 1: NP_609946.1
• Gene: l(2)37Cb / 35192
• FlyBaseID: FBgn0086444
• Length: 894
• Species: Drosophila melanogaster
• Sequence 2: NP_001072515.1
• Gene: dhx35 / 779970
• XenbaseID: XB-GENE-5868299
• Length: 701
• Species: Xenopus tropicalis
• Alignment Length: 656
• Identity: 303/656 - (46%)
• Similarity: 444/656 - (67%)
• Gaps: 19/656 - (2%)

  Fly   243 LTLDETRRSLPVYPFKEDLIAAVKEHQVLIIEGETGSGKTTQVPQYLVEAGFTKDKKMIGCTQPR 307
            |:::..|:.|||:..:..::..|:.:|.::|.||||.||:||:||||.|||:|.:.:::|.||||
 Frog    43 LSIEHQRQKLPVFKLRNHILYLVENYQTVVIIGETGCGKSTQIPQYLTEAGWTAEGRVVGVTQPR 107

  Fly   308 RVAAMSVAARVAEEMGVKLGNEVGYSIRFEDCTSDR-TILKYMTDGTLHREFLSEPDLASYSVMI 371
            ||||:|||.|||||.|..||:||||.|||:|||..: |.:|::|||.|.||.:|:|.|..|||::
 Frog   108 RVAAVSVAGRVAEERGAVLGHEVGYCIRFDDCTDPQATRIKFLTDGMLVREMMSDPLLTRYSVLM 172

  Fly   372 IDEAHERTLHTDILFGLVKDIARFRPELKLLISSATLDAEKFSAFF----------DDAPIFRIP 426
            :||||||||:|||..||:|.:.:.|.:|:|:::|||||||||.|||          |...|..:.
 Frog   173 LDEAHERTLYTDIAIGLLKKVQKKRGDLRLVVASATLDAEKFKAFFNQNDTNDPSRDTCAILTVE 237

  Fly   427 GRRYPVDIFYTKAPEADYIDACCVSVLQIHATQPLGDILVFLTGQDEIETCQEVLHDRVK---RL 488
            ||.:|||||||::|..||:.:...:|::||.:...||||.|||||:|:|:...:|.::.:   |.
 Frog   238 GRTFPVDIFYTQSPVPDYLKSTVQTVMKIHQSDLEGDILAFLTGQEEVESVVSMLVEQARILSRS 302

  Fly   489 GSKIRELIVIPVYANLPSDMQAKIFEPTPPNARKVILATNIAETSLTIDNIIYVIDPGFAKQNNF 553
            |.| :.|.|:|:||.||:..|.|:||....:||||::||||||.|:||:.|.:|||.||.|...:
 Frog   303 GMK-KHLRVLPMYAGLPTSEQMKVFERVSHSARKVVVATNIAEASITINGISFVIDCGFVKLRAY 366

  Fly   554 NSRTGMESLMVVPISKASANQRAGRAGRTAPGKCFRLYTAWAYKHELEDNTVPEIQRINLGNAVL 618
            :.:..:|||:|||:|:|||||||||:||...|:|:||||...:. :|..:||||:||.||...:|
 Frog   367 DPKRAVESLVVVPVSQASANQRAGRSGRNRSGQCYRLYTEEDFL-KLPPSTVPEMQRSNLAPVIL 430

  Fly   619 MLKALGINDLIHFDFLDPPPHETLVLALEQLYALGALNHHGELTK-LGRRMAEFPVDPMMGKMLL 682
            .||||||::::.|.||.|||.:::|.|||.|||||.|:.|..||: ||.||||||::||..||||
 Frog   431 QLKALGIDNVLRFHFLSPPPAQSMVQALELLYALGGLDKHCRLTEPLGVRMAEFPLNPMFAKMLL 495

  Fly   683 ASEKYKCSEEMVTIAAMLSVNSAIFYRPKDKIIHADTARKNFNHMHGDHLSLLQVYNQWAETDYS 747
            .|..:.||.|:::||||:.:.: ||..|.::...|....:.|....||||::|.|:..:.:.:.|
 Frog   496 ESGNFGCSAEILSIAAMMQIQN-IFVVPPNQKSQAIREHRKFAVEEGDHLTMLNVFEAFIKFNKS 559

  Fly   748 TQWCYENFIQYRSMKRARDVREQLVGLMQRVEIDMVSCLPETVNVRKAATAGYFYHVARLSKGGH 812
            :.||.:.|:.|:.:.||..|||||..|:.:.::...|...:...:.:...:|:|.:.|:|...|.
 Frog   560 SHWCQQRFLNYKGLMRAVTVREQLKKLLSKFKVPKNSSEGDPDPILRCIVSGFFANAAKLHSTGV 624

  Fly   813 YKTIKHNQTVMIHPNSSLF-EELPRWVLYHELVFTSKEYMRQVIEIESKWLLEVAPHYYKAKELE 876
            |:|::....:.|||.|.|: |:.|.|||:.|:|.|:|.|||.|..:||.||||:|||:|:.....
 Frog   625 YRTVRDGHELYIHPTSVLYAEKPPNWVLFSEVVQTNKYYMRDVTAVESAWLLELAPHFYQQGTHL 689

  Fly   877 DSTNKK 882
            ..|:|:
 Frog   690 SRTSKR 695

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
l(2)37Cb	NP_609946.1	PTZ00121	<6..267	CDD:173412	6/23 (26%)
		HrpA	251..>868	CDD:441249	296/632 (47%)
dhx35	NP_001072515.1	HrpA	52..>681	CDD:441249	296/631 (47%)