Protein Alignment l(2)37Cb and dhx9

DIOPT Version :10

• Sequence 1: NP_609946.1
• Gene: l(2)37Cb / 35192
• FlyBaseID: FBgn0086444
• Length: 894
• Species: Drosophila melanogaster
• Sequence 2: XP_002937403.1
• Gene: dhx9 / 733723
• XenbaseID: XB-GENE-967775
• Length: 1257
• Species: Xenopus tropicalis
• Alignment Length: 1065
• Identity: 279/1065 - (26%)
• Similarity: 435/1065 - (40%)
• Gaps: 258/1065 - (24%)

  Fly    22 EEESRLKDLQERDEFASRLKKRDDDRTRNVVDS--------TGGRRAIEEATKRL-------KLE 71
            |..:.|||.         ..|||:...:..::|        ..|...:|.|..||       |.:
 Frog   143 ERGANLKDY---------YAKRDEQEAQATLESEEVDLNAGLHGNWTLENAKARLNQFFQKEKTQ 198

  Fly    72 HEDR-DKIVP-HLR------------LQSRRQYLEKRKDDKVAELEADILDDEYLFDESV----- 117
            .|.: .::.| |.|            |..|....|...:.|:|.....:.....|:..||
 Frog   199 GEYKYSQVGPDHNRSFIAEMTLYVKQLGRRITAREHGSNKKLAAQSCALSIVRQLYHLSVIEPYS 263

  Fly   118 -LTKREKEEREYKKQL-LN--IAKEHEKARELERIQRYNMPQD------LKKGERSEYVEVDEFE 172
             |||:::.|.....|: ||  :.|:.:...:...|:....|||      |..|   :.|..:..:
 Frog   264 GLTKKKEGEAVEPYQVNLNPDVVKQLQSTIQELGIELPYPPQDPSQPVSLNLG---KLVHFEPSQ 325

  Fly   173 KQPNSEQKKWEAEQLASARFHFGAKDAKAEEEYELLLDDQIDFIQALTLDG----------SREK 227
            ||.:|....|...|                |.:.......||       :|          |.|.
 Frog   326 KQSHSGVVPWSPPQ----------------ENWNPWTSSNID-------EGPLAFAPQEQISAEL 367

  Fly   228 SSSRQPELTEKERKRLTLDETRRSLPVYPFKEDLIAAVKEHQVLIIEGETGSGKTTQVPQYLVEA 292
            .:.....:.:...|::.:|  |.||||..|:|:::.||....|:||.|.||.|||||||||:::.
 Frog   368 KNEHMYHMQDPNMKQVLID--RESLPVKKFEEEIMHAVHNSPVVIIRGATGCGKTTQVPQYILDE 430

  Fly   293 GFTKDKKM---IGCTQPRRVAAMSVAARVAEEMGVKLGNEVGYSIRFED-CTSDRTILKYMTDGT 353
            ....|:..   |..|||||::|:|||.|||.|.|.::|...|||:|||. .......:.:.|.|.
 Frog   431 CIRNDRAAQCNIVVTQPRRISAVSVAERVAFERGEEIGKSCGYSVRFESVLPRPHASMLFCTVGV 495

  Fly   354 LHREFLSEPDLASYSVMIIDEAHERTLHTDILFGLVKDIARFRPELKLLISSATLDAEKFSAFFD 418
            |.|:.  |..:...|.:|:||.|||.::||.|..:::|:.:..|::::::.|||:|...|..:|.
 Frog   496 LLRKL--EAGIRGISHVIVDEIHERDINTDFLLVVLRDVIQAFPDIRVILMSATIDTSMFCEYFF 558

  Fly   419 DAPIFRIPGRRYPVDIFY--------------------TKAPEA--------------DYIDACC 449
            :.||..:.||.:||..::                    .|..|.              ||.....
 Frog   559 NCPIIEVFGRTFPVQEYFLEDCIQMTQFIPPPRDKKKKDKDEEGGDDEETNCNLVCGDDYGPETR 623

  Fly   450 VSVLQIHATQ-PL----------------GDILVFLTGQDEIETCQEVLHDRVKRLGSKIRELIV 497
            .|:.|:...: ||                |.:||||.|.:.|...|:.| :.....||  ....:
 Frog   624 RSMSQLSEKETPLELIEALLKYIETLNVPGAVLVFLPGWNLIYAMQKHL-EMNPHFGS--HSYCI 685

  Fly   498 IPVYANLPSDMQAKIFEPTPPNARKVILATNIAETSLTIDNIIYVIDPGFAKQNNFNSRTGMESL 562
            :|:::.:|.|.|.|:|:|.|....||||:|||||||:||::::||||....|...|.|...|.:.
 Frog   686 LPLHSQIPRDEQRKVFDPVPDGIIKVILSTNIAETSITINDVVYVIDSCKQKVKLFTSHNNMTNY 750

  Fly   563 MVVPISKASANQRAGRAGRTAPGKCFRLYTAWAYKHELEDNTVPEIQRINLGNAVLMLKALGIND 627
            ..|..||.:..||.|||||..||.||.|.:...:: .||.:..|||.|..|....|.:|.|.:..
 Frog   751 ATVWASKTNLEQRKGRAGRVRPGFCFHLCSRARFE-RLETHLTPEIFRTPLHEVALSIKLLRLGG 814

  Fly   628 LIHF--DFLDPPPHETLVLALEQLYALGALNHHGELTKLGRRMAEFPVDPMMGKMLLASEKYKCS 690
            :..|  ..::|||.:.::.|...|..|.||:.:.|||.|||.:|:.|::|.:|||::....:...
 Frog   815 IGQFLSKAIEPPPLDAVIEAEHTLRELDALDSNDELTPLGRILAKLPIEPRLGKMMIMGCIFYVG 879

  Fly   691 EEMVTIAA-------MLSVNSAIFYRPKDKIIHADTARKNFNHMHGDHLSLLQVYNQWAET---- 744
            :.:.||:|       .:|....:.|      :|.:.|...|:    ||::||.|:..|.:.
 Frog   880 DALCTISAATCFPEPFISEGRRLGY------VHRNFAGNRFS----DHVALLSVFQAWDDARMGG 934

  Fly   745 -DYSTQWCYENFIQYRSMKRARDVREQLVGLMQRVEIDMVSCLPE-----------------TVN 791
             :..|::|....:...:::...:.:.||      .||.:.|..||                 .|.
 Frog   935 EEAETRFCEHKRLNMATLRMTWEAKVQL------KEILVNSGFPEECLMTQVFNNTGPDNNLDVV 993

  Fly   792 VRKAATAGY---FYHVAR---LSKGGHYKTIKHNQTVMIHPNSSLFEELPRWVLYHE-------- 842
            :...|...|   .||..:   |:..|....|..:.......|..|....|.:|...:
 Frog   994 ISLLAFGVYPNVCYHKEKRKILTTEGRNALIHKSSVNCPFSNQDLKYPSPFFVFSEKIRTRAISA 1058

  Fly   843 -----------LVFTSKEYMR--QVIEIESKWLLEVAPHYYKA-----------------KELE- 876
                       |:|.||:.|.  :.|.::. |:....||...|                 ||.|
 Frog  1059 KGMTMVSPLQLLLFASKKVMSDGEFILLDD-WIRLSLPHDESACITALRAALEALVVEVTKEPEI 1122

  Fly   877 ----DSTNKKM---------PKVAG 888
                |..|:||         |..||
 Frog  1123 LSQLDPVNEKMLNMIRLISKPSTAG 1147

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
l(2)37Cb	NP_609946.1	PTZ00121	<6..267	CDD:173412	63/298 (21%)
		HrpA	251..>868	CDD:441249	211/729 (29%)
dhx9	XP_002937403.1	DSRM_DHX9_rpt1	3..71	CDD:380683
		DSRM_DHX9_rpt2	181..255	CDD:380684	15/73 (21%)
		DEXHc_DHX9	333..565	CDD:350730	82/258 (32%)
		HrpA	388..>873	CDD:441249	169/490 (34%)
		HA2	840..921	CDD:214852	25/90 (28%)
		OB_NTP_bind	996..1075	CDD:400182	13/78 (17%)