Protein Alignment l(2)37Cb and Dqx1

DIOPT Version :10

• Sequence 1: NP_609946.1
• Gene: l(2)37Cb / 35192
• FlyBaseID: FBgn0086444
• Length: 894
• Species: Drosophila melanogaster
• Sequence 2: XP_038964267.1
• Gene: Dqx1 / 680434
• RGDID: 1591766
• Length: 780
• Species: Rattus norvegicus
• Alignment Length: 735
• Identity: 228/735 - (31%)
• Similarity: 359/735 - (48%)
• Gaps: 118/735 - (16%)

  Fly   247 ETRRSLPVYP----FKEDLIAAVKEHQVLIIEGETGSGKTTQVPQYLVE----AGFTKDKKMIGC 303
            |.||:||::.    |.|.|.::  ...|:::.||.||||:||:||:..|    .||...:  :..
  Rat    37 EQRRALPIWAARFLFLEHLESS--PTGVVLVSGEPGSGKSTQIPQWCAEFALARGFQTGQ--VTV 97

  Fly   304 TQPRRVAAMSVAARVAEEMGVKLGNEVGYSIRFEDCTSDRTILKYMTDGTLHREFLSEPDLASYS 368
            |||..:||||:|:|||:||.:.||:|:||||..||||...|:|::..|....:|..|.....::|
  Rat    98 TQPYPLAAMSLASRVADEMDLTLGHEIGYSIPQEDCTGPNTMLRFCWDRLFLQEVASTRGPGAWS 162

  Fly   369 VMIIDEAHERTLHTDILFGLVKDIARFR-----PELKLLISSATLDAEKFSAFFDDAPIFRIPGR 428
            |:::|||.||::.:|:|.||::| .|.|     |.:.::..||.  ..||.||:.::|...:|
  Rat   163 VLVLDEAQERSVASDLLQGLLRD-TRLRNLPGDPRVVIVTDSAL--EPKFQAFWGNSPTVHVP-- 222

  Fly   429 RYPVD---IFYTKAPEADYIDACCVSVLQI-HATQPLGDILVFLTGQDEIETCQEVLHDRVKRL- 488
            |.|.:   :.|.....||.::|.|.:||:: ...:..||:||:|..::||..|.|.|...:..|
  Rat   223 REPGENPTLTYKDTVPADLVEAACQAVLELCQREEAPGDVLVYLPSEEEISLCCESLSREMGMLA 287

  Fly   489 --GSKIRELIVIPVYANLPSDMQAKIFEPTPPNARKVILATNIAETSLTIDNIIYVIDPGFAKQN 551
              |...|   |:|::......:|. ::|.|..:.||:::...:|:.|.::..|.:|||.|...::
  Rat   288 VPGPLPR---VLPLHPGCGQAIQT-VYEDTDVSVRKIVVTHWLADFSFSLPFIQHVIDSGLELRS 348

  Fly   552 NFNSRTGMESLMVVPISKASANQRAGRAGRTAPGKCFRLYTAWAYKHELEDNTVPEIQRINLGNA 616
            .:|.|...||.::..|||..|..|..||....||.|.|||:......|......|::...||.:.
  Rat   349 VYNPRIRAESQVLRRISKCQAEARLLRARGFPPGTCLRLYSKSTLDLEAPPLPHPKVCEENLSSL 413

  Fly   617 VLMLKALGINDLIHFDFLDPPPHETLVLALEQLYALGALNHHGELTKLGRRMAEFPVDPMMGKML 681
            ||:||...|.:.....|||.|..|.|:.|||.|..|.||:..|:|:.||..::|||:.|.:.|.|
  Rat   414 VLLLKRKQIAEPGECHFLDRPAPEALMQALEDLDYLAALDDDGDLSDLGIILSEFPLPPELAKAL 478

  Fly   682 LASEKYKCSEEMVTIAAMLSVNSAIFYRPKDKIIHADTA-RKNFNHMHGDHLSLLQVYNQWAETD 745
            |||.::.|.:||:|:||||:.... |.||  .:...:.| |:...|..|||.||:|||..:.::.
  Rat   479 LASCEFNCVDEMLTLAAMLTAAPG-FTRP--PLCAGEAALRRGLEHADGDHSSLIQVYEAFVQSG 540

  Fly   746 YSTQWCYENFIQYRSMKRARDVREQLVGLMQRVEIDMVSCLP------ETVNVRKAATAGYFY-- 802
            ....||....:.:.::.:||.:|.:|:.||||:|:.:  .||      ...:::||..:|||.
  Rat   541 ADETWCQARGLSWEALCQARKLRAELLELMQRIELPL--SLPAFGSEQNRRDLQKALLSGYFLKA 603

  Fly   803 -------------------------------------------------------------HVAR 806
                                                                         .|||
  Rat   604 MMRRGLMSKLPSDSLSTSGWPQTAPLAPYSATQAGITATPALAFFIFCASLLSPPMYLCFNEVAR 668

  Fly   807 LSKG-GHYKTIKHNQTVMIHP-----NSSLFEELPRWVLYHELVFTSKEYMRQVIEIESKWLLEV 865
            .:.| |:|..:.|.....:.|     |.....:.|.|||||....:....:..|.||:.:.|:|:
  Rat   669 DTDGTGNYLLLTHKHVAQLSPYCVYRNRRTPAQPPTWVLYHRFSISKDNCLCTVSEIQPEMLVEL 733

  Fly   866 APHYYKA----KELEDSTNK 881
            ||.|:.:    .|..|..|:
  Rat   734 APPYFLSNLPPSESRDLLNQ 753

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
l(2)37Cb	NP_609946.1	PTZ00121	<6..267	CDD:173412	8/23 (35%)
		HrpA	251..>868	CDD:441249	220/712 (31%)
Dqx1	XP_038964267.1	HrpA	41..>498	CDD:441249	166/469 (35%)
		DEAD-like_helicase_N	42..221	CDD:475120	70/185 (38%)
		OB_NTP_bind	662..737	CDD:400182	22/74 (30%)