| Sequence 1: | NP_609946.1 | Gene: | l(2)37Cb / 35192 | FlyBaseID: | FBgn0086444 | Length: | 894 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | XP_011541883.1 | Gene: | YTHDC2 / 64848 | HGNCID: | 24721 | Length: | 1439 | Species: | Homo sapiens |
| Alignment Length: | 1136 | Identity: | 280/1136 - (24%) |
|---|---|---|---|
| Similarity: | 453/1136 - (39%) | Gaps: | 370/1136 - (32%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 56 GGRRAIEEATKRLKLEHEDRDKIVPHLRLQSRRQYLEKRKDDKVAELEADILDDEYLFDESVLTK 120
Fly 121 REKEEREYKKQLLNIAKEHEKARELERIQRYNMPQDLKKGE-RSEYVEVDEFEKQPNSEQKKWEA 184
Fly 185 EQLASARFHFGAKDA----------KAEEEYELLLDDQIDFIQALTLDGSRE--KSSSRQ----P 233
Fly 234 ELTEKERKRLTLDETRRSLPVYPFKEDLIAAVKEHQVLIIEGETGSGKTTQVPQYLVEAGFTKD- 297
Fly 298 KKMIGCTQPRRVAAMSVAARVAEEMGVKLGNEVGYSIRFEDCTSDRTILKYMTDGTLHREFLS-E 361
Fly 362 PDLASYSVMIIDEAHERTLHTDILFGLVKDIARFRPELKLLISSATLDAEKFSAFFDDAPIFRIP 426
Fly 427 GRRYPV----------------------------------------------------------- 432
Fly 433 ------------DIFYTKAPEADY----------IDACC-----------------------VSV 452
Fly 453 -------------------------------LQIH-----------------------------A 457
Fly 458 TQPLGD------------------------------------------------------ILVFL 468
Fly 469 TGQDEIETCQEVLHDRV----KRLGSKIRELIVIPVYANLPSDMQAKIFEPTPPNARKVILATNI 529
Fly 530 AETSLTIDNIIYVIDPGFAKQNNFNSRTGMESLMVVPISKASANQRAGRAGRTAPGKCFRLYTAW 594
Fly 595 AYKHELEDNTVPEIQRINLGNAVLMLKALGINDLIHFDFL----DPPPHETLVLALEQLYALGAL 655
Fly 656 NHHGELTKLGRRMAEFPVDPMMGKMLLASEKYKCSEEMVTIAAMLSVNSAIFYRPKDKII----- 715
Fly 716 ----HADTARKNFN-HMHGDHLSLLQVYNQW--AETD-YSTQWCYENFIQYRSMKRARDVREQLV 772
Fly 773 GLMQRV---------EIDMVSCLPETVNVRKAA-TAGYFYHVARLSKGGHYKTIKHNQTVMIHPN 827
Fly 828 SSL----FEELP--------------RWVLYHE---------------------LVFTSKEYM-R 852
Fly 853 QVIEIESKWLLEVAPHYYKAKELEDSTNKKM 883 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| l(2)37Cb | NP_609946.1 | HrpA | 222..867 | CDD:224557 | 238/941 (25%) |
| DEXDc | 269..408 | CDD:238005 | 61/140 (44%) | ||
| HELICc | 491..581 | CDD:197757 | 36/89 (40%) | ||
| HA2 | 651..735 | CDD:214852 | 28/93 (30%) | ||
| OB_NTP_bind | 770..869 | CDD:285018 | 27/148 (18%) | ||
| YTHDC2 | XP_011541883.1 | R3H_DEXH_helicase | 46..104 | CDD:100077 | 20/96 (21%) |
| HrpA | 189..>1016 | CDD:224557 | 221/839 (26%) | ||
| DEXHc_YTHDC2 | 193..368 | CDD:350745 | 72/174 (41%) | ||
| ANK repeat | 505..537 | CDD:293786 | 1/31 (3%) | ||
| ANK repeat | 539..564 | CDD:293786 | 0/24 (0%) | ||
| OB_NTP_bind | 971..1066 | CDD:369483 | 18/94 (19%) | ||
| YTH | 1288..1404 | CDD:367840 | |||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 1 | 0.900 | - | - | E1_COG1643 | |
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 2 | 1.810 | |||||