Protein Alignment l(2)37Cb and dhx30

DIOPT Version :10

• Sequence 1: NP_609946.1
• Gene: l(2)37Cb / 35192
• FlyBaseID: FBgn0086444
• Length: 894
• Species: Drosophila melanogaster
• Sequence 2: XP_699339.5
• Gene: dhx30 / 570735
• ZFINID: ZDB-GENE-130530-833
• Length: 1173
• Species: Danio rerio
• Alignment Length: 1045
• Identity: 272/1045 - (26%)
• Similarity: 445/1045 - (42%)
• Gaps: 294/1045 - (28%)

  Fly     3 GKNRKRTASSSSSGEEP---DSEEESRLKDLQERDEFASRLKKRDDDRTRNVVD----------- 53
            ||.|:..........:.   |:|||:.|:.|..:       ||...||...:|:
Zfish   141 GKRRQEAGMLRMKDRQTSLCDNEEENHLQSLPIQ-------KKTQKDRAHGLVEEDSRLSEALAI 198

  Fly    54 ----------------------------STGGRRAIEE------------ATKRLKLEHEDRDKI 78
                                        ::||:..:.|            |:.|.:||.|.....
Zfish   199 FPRPRTLLGSVIQVATSSCRVRDLLQYKTSGGKVKVCELNVLWPTPMTFTASGRRRLEAEANAAA 263

  Fly    79 VPHLRLQSRRQYLEKRKDDKVAELEADILDDEYLFDESVLTKREKEEREYKKQLLNIAKEHEK-- 141
            :..|:|:                 |.::||::        .|.....|.::.|:....:.|.:
Zfish   264 LACLKLK-----------------ELNLLDEQ--------NKPLTHARYHQDQVREAGERHRQPC 303

  Fly   142 ----ARELE-RIQRYNMPQDLKKGERSEY-VEVDEFEKQPNSEQKKWEAEQLASARFHFGAKDAK 200
                ..:|| |||:|          .|:| ||.:        .||.|:.|:      |..:..:.
Zfish   304 RMQIPEQLELRIQQY----------LSQYPVEAE--------VQKLWDEEE------HQSSSIST 344

  Fly   201 AEEEYELLLDDQIDFI-QALTLDGSREKSSSRQPELTEKERKRLTLDETRR-------SLPVYPF 257
            |.::|     |:.:|| .|:|....|    :.:|:..|...:|| |...:|       .|||...
Zfish   345 AADDY-----DEDEFITDAITSKPYR----ALEPKEAEHLSQRL-LSMWKRVGPARGAELPVDAH 399

  Fly   258 KEDLIAAVKEHQVLIIEGETGSGKTTQVPQYLVEAGFTKDKKM---IGCTQPRRVAAMSVAARVA 319
            ||.::.||:..||::|.||||.||||::|::|:|.|..:.:..   :..|||||::|:|||.|||
Zfish   400 KESILEAVRSSQVVVISGETGCGKTTRIPRFLLEDGVLRGEGAECNVLVTQPRRISAVSVAQRVA 464

  Fly   320 EEMGVKLGNEVGYSIRFEDCTSDRT--ILKYMTDGTLHREFLSEPDLASYSVMIIDEAHERTLHT 382
            .|:|..|.:.|||.:|.|....:|:  .|.::|.|.|.::..|.|.|...|.:|:||.|||.:.|
Zfish   465 HEIGPALQHCVGYQVRLESRPPERSGGALLFLTLGVLLKKLQSNPRLEGISHVIVDEVHERDVQT 529

  Fly   383 DILFGLVKDIARFRPELKLLISSATLDAEKFSAFFDDAPIFRIPGRRYPV--------------- 432
            |:|..|::.:...|||||:|:.||:.|:::.:.:|...|:.|:||..:||
Zfish   530 DLLLHLLRCVLSLRPELKVLLMSASGDSQRLAQYFGGCPVLRVPGFMHPVRARFLEDMQLDSRRP 594

  Fly   433 --DIFYTK----------------APE----ADYIDACCVSVLQIHATQPLGDILVFLTGQDEIE 475
              |:..|:                .|:    ||.||       .||.|...|.:|.||.|..||:
Zfish   595 LLDMGSTQWSAEVRGRMGKEENNVTPDLDLVADVID-------HIHRTGEPGAVLCFLPGWQEIK 652

  Fly   476 TCQEVLHDR-VKRLGSKIRELIVIPVYANLPSDMQAKIFEPTPPNARKVILATNIAETSLTIDNI 539
            ..|:.|.:: ..|.||:    |::|:::::....|..:|:..|...||::|||||||||:|||:|
Zfish   653 AVQQQLEEKQAYRSGSQ----IILPLHSSMAVSEQQVVFQRPPAGQRKIVLATNIAETSITIDDI 713

  Fly   540 IYVIDPGFAKQNNFNSRTGMESLMVVPISKASANQRAGRAGRTAPGKCFRLYTAWAYKHELEDNT 604
            ::|:|.|..|:.|::.||.:.:|..|.||:|:..||.|||||..||..:.|:.. .....:|...
Zfish   714 VHVVDAGVQKEQNYDPRTKVSALNTVWISQANVTQRRGRAGRCQPGHSYHLFPR-KQLERMEPFP 777

  Fly   605 VPEIQRINLGNAVLMLKALGINDLIHF------DF----LDPPPHETLVLALEQLYALGALNHHG 659
            ||||.|..|.:.|:..|       ||.      ||    ||.|..:.:..|::.|..:|.|:...
Zfish   778 VPEILRTPLESVVMQAK-------IHCPESKAEDFLSQVLDSPDTQAVRTAVKNLMDIGVLDASE 835

  Fly   660 ELTKLGRRMAEFPVDPMMGKMLLASEKYKCSEEMVTIAAMLSVNSAIFYRPKDKIIHADTARKNF 724
            :||.||..::....||.:||:|:.|..:.|.:.::::.|.|:.:.  ||...........|:...
Zfish   836 DLTPLGHHVSCMSCDPRLGKVLVFSALFSCVQPVLSVVACLTRDP--FYNSLQNRTLVSKAKAEL 898

  Fly   725 NHMHG-DHLSLLQVYNQWAETDYSTQWCYENFIQYRSMKRARDVREQLV--------------GL 774
            :...| |:|...:|...|.|                  :.:||.|:..:              ||
Zfish   899 SGSSGSDYLVFSRVVQSWRE------------------QHSRDSRQDYLDKHTLSGASLRFIHGL 945

  Fly   775 MQRVEIDM---------VSC--LPETVN--------VRKAATAGYFYHVARLSKG-----GHYKT 815
            ||:...::         ..|  |...||        :.....||.:.::.::.||     |.::.
Zfish   946 MQQFSDNLCEAGLVDHSAECLRLSSPVNQQSKEEQLITAVLLAGLYPNLIQVKKGVVTKSGRFRA 1010

  Fly   816 IKHNQTVMIHPNSSLFEELPRWVLYHELVFTSKEYMRQVIEIESKWLLEVAPHYYKAKE------ 874
                      .|.|...|....:|:...|...|::      :.|:||.     ::.|.:
Zfish  1011 ----------ENVSFRTESGPVLLHRSSVNRDKQH------LWSRWLT-----FFSAVKSSGQVF 1054

  Fly   875 LEDST 879
            :.|||
Zfish  1055 IRDST 1059

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
l(2)37Cb	NP_609946.1	PTZ00121	<6..267	CDD:173412	65/330 (20%)
		HrpA	251..>868	CDD:441249	208/708 (29%)
dhx30	XP_699339.5	HrpA	388..>930	CDD:441249	186/580 (32%)
		OB_NTP_bind	982..1069	CDD:400182	18/99 (18%)