Protein Alignment l(2)37Cb and dhx36

DIOPT Version :10

• Sequence 1: NP_609946.1
• Gene: l(2)37Cb / 35192
• FlyBaseID: FBgn0086444
• Length: 894
• Species: Drosophila melanogaster
• Sequence 2: NP_001122016.3
• Gene: dhx36 / 569072
• ZFINID: ZDB-GENE-050419-20
• Length: 1037
• Species: Danio rerio
• Alignment Length: 968
• Identity: 276/968 - (28%)
• Similarity: 439/968 - (45%)
• Gaps: 216/968 - (22%)

  Fly    69 KLEHEDRDKIVPHLRLQSRRQYLEKRKDDKVAELEADILDDEYLFDESVLTKREKEEREYKKQLL 133
            |.|.|.|.:.|.|:                               |||    |||    :..|||
Zfish    81 KSEAERRSRAVVHM-------------------------------DES----REK----HITQLL 106

  Fly   134 NIAKEHEKARELERIQRYNMPQDLKKGERS---------EYVEVDEFEKQPNSEQKKWEAEQLAS 189
            |..:     |:|.|....:..|..:..:.:         :.||.......|..|.|..:.|....
Zfish   107 NTVQ-----RDLGRDVHPSTSQSWRNKDEARGHSYFDGDDPVETQNIMPLPKVEPKDEKQEDAIK 166

  Fly   190 ARFHFGAKDAKAEEEYELLLDD--QIDFIQALTLDGSREKSSSRQPELTEKERKRLTLDETRRSL 252
            :|  ...|:...|...|.||.|  ||.|     ||...:|...::    |.....:.:.:.|:.|
Zfish   167 SR--ASLKEELNETNLEYLLQDVVQIPF-----LDEELKKDQQKK----EDNAAYIEMLKFRKKL 220

  Fly   253 PVYPFKEDLIAAVKEHQVLIIEGETGSGKTTQVPQYLVEAGFTKDKK---MIGCTQPRRVAAMSV 314
            |.|..:|:|:..:..::||:|.||||.||||||.|::::....:.:.   .:.||||||::|:||
Zfish   221 PSYGMREELVRLISANRVLVISGETGCGKTTQVTQFILDDFIQRGQGSLCRVVCTQPRRISAISV 285

  Fly   315 AARVAEEMG--VKLGNEVGYSIRFED-CTSDRTILKYMTDGTLHREFLSEPDLASYSVMIIDEAH 376
            |.|||.|..  |..|...||.||.:. ....:..|.|.|.|.:.:...|:|.|:|.:.:::||.|
Zfish   286 AERVAVERAEPVGEGKSCGYQIRLQSRLPRKQGSLLYCTTGVILQWLHSDPYLSSITHLVLDEIH 350

  Fly   377 ERTLHTDILFGLVKDIARFRPELKLLISSATLDAEKFSAFFDDAPIFRIPGRRYPVDIF------ 435
            ||::.:|||..:|||:...|.:||:::.||||:|||||.:|::.|:..|||..:||..:
Zfish   351 ERSVQSDILITIVKDLLTARDDLKVVLMSATLNAEKFSKYFNNCPMIHIPGYTFPVTEYLLEDVV 415

  Fly   436 ---------------YTK--------APEADYIDA-------CCVSVLQ---------------- 454
                           |.|        .||...|:|       |....|:
Zfish   416 ELLGFQPRYKQRKPHYRKRNNHGSSARPEKGKIEAKYHESWPCYARTLRDRFSDTTIEVLGMMDD 480

  Fly   455 ---------------IHATQPLGDILVFLTGQDEIETCQEVL-HDRVKRLGSKIRELIVIPVYAN 503
                           |...:..|.|||||.|.|.|.|..::| .|::.:.|.  ...|:||:::.
Zfish   481 DDNIDLELTAALIRHIAVNENEGAILVFLPGWDNISTLNDLLMSDQMFKSGR--YRFIIIPLHSL 543

  Fly   504 LPSDMQA-------KIFEPTPPNARKVILATNIAETSLTIDNIIYVIDPGFAKQNNFNSRTGMES 561
            :|:..|.       ::|:..||..||:::||||||||:|||:::||||.|..|:.:|:::..:.:
Zfish   544 MPTVSQTQVISLFPQVFKKPPPGVRKIVIATNIAETSITIDDVVYVIDGGKIKETHFDTQNNIRT 608

  Fly   562 LMVVPISKASANQRAGRAGRTAPGKCFRLYTAWAYKHELEDN-TVPEIQRINLGNAVLMLKALGI 625
            :....:|.|:|.||.|||||.:||||:.||.  ..:..|.|| .:|||||..|....|.:|.|.:
Zfish   609 MTAEWVSIANAKQRKGRAGRVSPGKCYHLYN--GLRASLLDNYQLPEIQRTPLEELCLQIKVLKL 671

  Fly   626 NDLIHF--DFLDPPPHETLVLALEQLYALGALNHHGELTKLGRRMAEFPVDPMMGKMLLASEKYK 688
            ..:..|  ..:|||....:.||:..|..|.||:...:||.||..:|..||:|.:|||:|......
Zfish   672 GPIATFLQKTMDPPSDRAIELAITHLVDLNALDRDEKLTPLGFHLARMPVEPHIGKMILFGALLG 736

  Fly   689 CSEEMVTIAAMLSVNSAIFYRP--KDKIIHADTARKNFN-HMHGDHLSLLQVYNQWAE-----TD 745
            |.:.::||||.||.... |:.|  |:||  ||..||.|: :...||||::..:..|.:     :.
Zfish   737 CLDPVLTIAASLSFKDP-FFIPLGKEKI--ADQRRKMFSQNSRSDHLSIVNAFLGWEDAKRQGSR 798

  Fly   746 YSTQWCYENFIQYRSMKRARDVREQLVGLMQRVEIDMVSCLPE----TVN------VRKAATAGY 800
            :..::|::||:...:::..::::.|....:.|... :.|..|:    .:|      |:....||.
Zfish   799 FEREYCWDNFLSANTLQMLQNMKGQFAEHLLRAGF-VNSKDPKDPSSNINSENKKLVKAVIVAGL 862

  Fly   801 FYHVARLSKGGHYKT-------IKHNQTVMIHPNSSLFEELP---RWVLYHELVFTSKEYMRQVI 855
            :..||::|...:.|.       .|.:..|.|||.|...||..   :|::||..:.|:..::....
Zfish   863 YPKVAKISPSHNKKRPMPVKVYTKADGKVCIHPKSVNAEETQFQYKWLVYHLKMKTTSIFLYDCT 927

  Fly   856 EIE------------------------SKWLLEVAP----HYYK--AKELEDSTNKKM 883
            |:.                        .:|::..:|    |..|  .|||:....:|:
Zfish   928 EVSPFSLLFFGGNISIQRDQDQDTIAVDEWIVFQSPGRIAHLVKDLKKELDVLLEEKI 985

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
l(2)37Cb	NP_609946.1	PTZ00121	<6..267	CDD:173412	46/208 (22%)
		HrpA	251..>868	CDD:441249	229/756 (30%)
dhx36	NP_001122016.3	None