Protein Alignment l(2)37Cb and pea

DIOPT Version :9

• Sequence 1: NP_609946.1
• Gene: l(2)37Cb / 35192
• FlyBaseID: FBgn0086444
• Length: 894
• Species: Drosophila melanogaster
• Sequence 2: NP_610928.1
• Gene: pea / 36561
• FlyBaseID: FBgn0086895
• Length: 1242
• Species: Drosophila melanogaster
• Alignment Length: 1002
• Identity: 442/1002 - (44%)
• Similarity: 605/1002 - (60%)
• Gaps: 129/1002 - (12%)

  Fly     4 KNRKRTASSSSSGEEPDSEEESRLKDLQERDEFASRLKKRD-------------DD--------- 46
            ::|.|...||||.:..:....||.:..:.||.   |.:.||             ||
  Fly   229 RDRDRRHKSSSSRDHHERRRRSRSRSTERRDR---RDRSRDCSEKMPPPSAAMTDDPEAGKIYSG 290

  Fly    47 RTRNV------VDSTGGRRAIEEATKRLKLEHEDR----DKIVPH--------LRLQSRRQYLEK 93
            :..|:      |...|.|:..|......:|..|.|    .::|..        :.:..::..|..
  Fly   291 KIANIVPFGCFVQLFGLRKRWEGLVHISQLRAEGRVTDVTEVVTRNQTVKVKVMSITGQKVSLSM 355

  Fly    94 RKDDKVAELEADILDDEYLFDESVLTKREKEEREYKKQLLNI------AKEHEKARELERI---Q 149
            ::.|:.:..:.:.|......|||:..:...........:||:      ..|||..:.:.||   :
  Fly   356 KEVDQDSGKDLNPLSHAPEDDESLRDRNPDGPFSSSTSMLNLQGNGMEGDEHESRKRVTRISSPE 420

  Fly   150 RYNMPQDLKKG--ERSEYVEVD-EFEKQPNSEQKKWEAE-------------------------- 185
            |:.:.|.:..|  :|||..:.| |....|..|..:.:.|
  Fly   421 RWEIKQMISSGVLDRSEMPDFDEETGLLPKDEDDEADIEIEIVEEEPPFLSGHGRALHDLSPVRI 485

  Fly   186 ------QLASARFHFGAKDAKAEEEYELLLDDQID---------FIQALTLDGSREKSSSRQ--- 232
                  .||.|.....|...:..|:..|..:.:|:         :|..|..|.||..:::.:
  Fly   486 VKNPDGSLAQAAMMQSALSKERREQKMLQREQEIEAMPTSLNKNWIDPLPEDESRSLAANMRGMA 550

  Fly   233 ---PELTE-------------KERKRLTLDETRRSLPVYPFKEDLIAAVKEHQVLIIEGETGSGK 281
               ||:.|             .::..|||.|.|:|||:|..::|||.||.::|:||:.|||||||
  Fly   551 AAPPEVPEWKKHVIGGKKSSFGKKTDLTLVEQRQSLPIYKLRDDLIKAVTDNQILIVIGETGSGK 615

  Fly   282 TTQVPQYLVEAGFTKDKKMIGCTQPRRVAAMSVAARVAEEMGVKLGNEVGYSIRFEDCTSDRTIL 346
            |||:.|||.|.|||...| |||||||||||||||.|||||.|.:||.||||:||||||||..||:
  Fly   616 TTQITQYLGECGFTARGK-IGCTQPRRVAAMSVAKRVAEEYGCRLGQEVGYTIRFEDCTSPETII 679

  Fly   347 KYMTDGTLHREFLSEPDLASYSVMIIDEAHERTLHTDILFGLVKDIARFRPELKLLISSATLDAE 411
            ||||||.|.||.|.|.:|.||||:::|||||||:|||:||||:|...:.||||||:::||||||.
  Fly   680 KYMTDGMLLRECLMEAELKSYSVIMLDEAHERTIHTDVLFGLLKTAVQKRPELKLIVTSATLDAV 744

  Fly   412 KFSAFFDDAPIFRIPGRRYPVDIFYTKAPEADYIDACCVSVLQIHATQPLGDILVFLTGQDEIET 476
            |||.:|..||||.||||.:||::.|||.||.||:||..::|:|||..:|.||||:|||||:||:|
  Fly   745 KFSQYFFKAPIFTIPGRTFPVEVLYTKEPETDYLDASLITVMQIHLREPPGDILLFLTGQEEIDT 809

  Fly   477 CQEVLHDRVKRLGSKIRELIVIPVYANLPSDMQAKIFEPTPPNARKVILATNIAETSLTIDNIIY 541
            ..|:|::|:|.||..:.|||::|||:.|||:||.:||:|.|..:|||::||||||||||||.|.|
  Fly   810 ACEILYERMKSLGPDVPELIILPVYSALPSEMQTRIFDPAPAGSRKVVIATNIAETSLTIDGIFY 874

  Fly   542 VIDPGFAKQNNFNSRTGMESLMVVPISKASANQRAGRAGRTAPGKCFRLYTAWAYKHELEDNTVP 606
            |:||||.||..:||:|||:||:|.|||:|:|.|||||||||.|||.:||||..||:.|:....||
  Fly   875 VVDPGFVKQKVYNSKTGMDSLVVTPISQAAAKQRAGRAGRTGPGKTYRLYTERAYRDEMLPTPVP 939

  Fly   607 EIQRINLGNAVLMLKALGINDLIHFDFLDPPPHETLVLALEQLYALGALNHHGELTKLGRRMAEF 671
            ||||.||...||.||.:|||||:||||:|.||.|:||:|||||::|.||:..|.||:||||||||
  Fly   940 EIQRTNLATTVLQLKTMGINDLLHFDFMDAPPVESLVMALEQLHSLSALDDEGLLTRLGRRMAEF 1004

  Fly   672 PVDPMMGKMLLASEKYKCSEEMVTIAAMLSVNSAIFYRPKDKIIHADTARKNFNHMHGDHLSLLQ 736
            |::|.:.|||:.|...:||:|::||.:||||.: :|||||||...||..:..||...||||:||.
  Fly  1005 PLEPNLSKMLIMSVALQCSDEILTIVSMLSVQN-VFYRPKDKQALADQKKAKFNQAEGDHLTLLA 1068

  Fly   737 VYNQWAETDYSTQWCYENFIQYRSMKRARDVREQLVGLMQRVEIDMVSCLPETVNVRKAATAGYF 801
            |||.|....:|..||||||:|.|::||::|||:||:|:|.|.::|:||....:|.::||..:|:|
  Fly  1069 VYNSWKNNKFSNAWCYENFVQIRTLKRSQDVRKQLLGIMDRHKLDVVSAGKNSVRIQKAICSGFF 1133

  Fly   802 YHVARLSKGGHYKTIKHNQTVMIHPNSSLFEELPRWVLYHELVFTSKEYMRQVIEIESKWLLEVA 866
            .:.|:......|:|:..:|.|.|||:|:||...|.||:|||||.|:|||||:|..|:.|||:|.|
  Fly  1134 RNAAKKDPQEGYRTLVDSQVVYIHPSSALFNRQPEWVIYHELVQTTKEYMREVTTIDPKWLVEFA 1198

  Fly   867 PHYY------------KAKELEDSTNK 881
            |.::            |.:.||...||
  Fly  1199 PSFFRFSDPTKLSKFKKNQRLEPLYNK 1225

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
l(2)37Cb	NP_609946.1	HrpA	222..867	CDD:224557	378/663 (57%)
		DEXDc	269..408	CDD:238005	97/138 (70%)
		HELICc	491..581	CDD:197757	58/89 (65%)
		HA2	651..735	CDD:214852	44/83 (53%)
		OB_NTP_bind	770..869	CDD:285018	46/98 (47%)
pea	NP_610928.1	S1_DHX8_helicase	285..363	CDD:240189	11/77 (14%)
		HrpA	573..1221	CDD:224557	376/649 (58%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45468086
Domainoid	1	1.000	55	1.000	Domainoid score	I637
eggNOG	1	0.900	-	-		E1_COG1643
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	234	1.000	Inparanoid score	I130
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D13788at6656
OrthoFinder	1	1.000	-	-		FOG0000059
OrthoInspector	1	1.000	-	-		otm51353
orthoMCL	1	0.900	-	-		OOG6_100085
Panther	1	1.100	-	-	P	PTHR18934
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X141
	11	10.800