Protein Alignment l(2)37Cb and l(1)G0007

DIOPT Version :9

• Sequence 1: NP_609946.1
• Gene: l(2)37Cb / 35192
• FlyBaseID: FBgn0086444
• Length: 894
• Species: Drosophila melanogaster
• Sequence 2: NP_572947.1
• Gene: l(1)G0007 / 32373
• FlyBaseID: FBgn0026713
• Length: 1222
• Species: Drosophila melanogaster
• Alignment Length: 1041
• Identity: 388/1041 - (37%)
• Similarity: 567/1041 - (54%)
• Gaps: 170/1041 - (16%)

  Fly     4 KNRKRTASSSSSGE------------------EPDSEEESRLKDLQERDEFAS--RLKKRDDDRT 48
            ::|||...||::.|                  :.|.:.:.|....:|||...|  |.:.||.||.
  Fly   141 RDRKRGPVSSTAAEGRDRDRDWDRDRRRDRDRDRDRDRDRRQHRERERDRHRSWDRDRGRDRDRD 205

  Fly    49 RNVVD--------------STGG--RRAIEEATKRLKLEHEDRDKIVPHLRLQ-----------S 86
            |::.:              |:||  ..:.::..........|.|...|.....           |
  Fly   206 RSMSERSVHTPREPGTPGGSSGGISNSSWDDEDGEFGQRKSDWDMPTPRRHGNKSGDWSVRSGGS 270

  Fly    87 RRQYLEKRKDDKVAELEADILDD-----------EYLFDESVLTKREKEEREYKKQLLNIAKEHE 140
            ||.:  .|:||.|....|...:.           .:..|...|...|:|:|...::..||.:.::
  Fly   271 RRNH--GRQDDTVRPTPAHRYNQWAHGRKRSGATPWGEDPESLDLWEEEQRRLDREWYNIDEGYD 333

  Fly   141 KARELERIQRYNMPQDLKKGERSEYVE------VDEFEKQPNSEQKKWEAEQ--------LASAR 191
                 :....:..|......:|.|.:|      :...::|.|.:.:.||..:        |.|..
  Fly   334 -----DENNPFGGPNSEYFRKREEQLEQKRTKRISAQQRQNNRDNELWERNRMLTSGVVTLISVN 393

  Fly   192 FHFGAKDAKAEEEYELL--------LDDQIDF----------------IQALTLDGS-------- 224
            ..|   |.:|.|...||        ||.:|.|                :..|...||
  Fly   394 DDF---DEEALERVHLLVHHIIPPFLDGRIVFTKQPEPVVPVKDPTSDMALLARKGSALVRNYRE 455

  Fly   225 ---REKSSSRQPELT-----------------------EKER----------------------- 240
               |.|:..:..||:                       ||::
  Fly   456 QKERRKAQKKHWELSGTKLGNIMGVQRPQDEDDMRFDKEKDKADYRKDQKFADHMRDQDTGGKSD 520

  Fly   241 --KRLTLDETRRSLPVYPFKEDLIAAVKEHQVLIIEGETGSGKTTQVPQYLVEAGFTKDKKMIGC 303
              ::.|:.|.||.|||:..:::|:..::|:.|:||.||||||||||:.|||.|.|::| :.||||
  Fly   521 FSRKKTISEQRRFLPVFASRQELLNVIRENSVIIIVGETGSGKTTQLTQYLHEDGYSK-RGMIGC 584

  Fly   304 TQPRRVAAMSVAARVAEEMGVKLGNEVGYSIRFEDCTSDRTILKYMTDGTLHREFLSEPDLASYS 368
            ||||||||||||.||::||..:||.:|||:||||||||:||::||||||.|.||.|.:|:|.|||
  Fly   585 TQPRRVAAMSVAKRVSDEMDTQLGEDVGYAIRFEDCTSERTVIKYMTDGILLRESLRDPELDSYS 649

  Fly   369 VMIIDEAHERTLHTDILFGLVKDIARFRPELKLLISSATLDAEKFSAFFDDAPIFRIPGRRYPVD 433
            .:|:||||||:|.||:||||:::|...|.:|||:::|||:|:.||:.||.:.|.|.||||.:|||
  Fly   650 AIIMDEAHERSLSTDVLFGLLREIVARRHDLKLIVTSATMDSSKFATFFGNVPTFTIPGRTFPVD 714

  Fly   434 IFYTKAPEADYIDACCVSVLQIHATQPLGDILVFLTGQDEIETCQEVLHDRVKRLGSKIRELIVI 498
            :.::|....||:::.....||:|.|...||:|:|:.||::||...|||.:|:..: .....|.::
  Fly   715 VMFSKNTCEDYVESAVKQALQVHLTPNEGDMLIFMPGQEDIEVTCEVLEERLAEI-DNAPALSIL 778

  Fly   499 PVYANLPSDMQAKIFEPTPPNARKVILATNIAETSLTIDNIIYVIDPGFAKQNNFNSRTGMESLM 563
            |:|:.||||:|||||:.:....||.::||||||||||:|.||||||.|:.|...:|.|.||::|.
  Fly   779 PIYSQLPSDLQAKIFQKSSDGLRKCVVATNIAETSLTVDGIIYVIDSGYCKLKVYNPRIGMDALQ 843

  Fly   564 VVPISKASANQRAGRAGRTAPGKCFRLYTAWAYKHELEDNTVPEIQRINLGNAVLMLKALGINDL 628
            :.|||:|:||||:||||||.||:.:||||...||.||...|||||||.||.|.||:||:||:.||
  Fly   844 IYPISQANANQRSGRAGRTGPGQAYRLYTQRQYKDELLALTVPEIQRTNLANTVLLLKSLGVVDL 908

  Fly   629 IHFDFLDPPPHETLVLALEQLYALGALNHHGELTKLGRRMAEFPVDPMMGKMLLASEKYKCSEEM 693
            :.|.|:||||.:.::.:|.||:.||||:|.|.||.|||:|||||:||...:||:.:.:..||.|:
  Fly   909 LQFHFMDPPPQDNILNSLYQLWILGALDHTGALTTLGRQMAEFPLDPPQCQMLIVACRMGCSAEV 973

  Fly   694 VTIAAMLSVNSAIFYRPKDKIIHADTARKNFNHMHGDHLSLLQVYNQWAETDYSTQWCYENFIQY 758
            :.|.:||||.| ||||||.:...||..|:.|.....|||:.|.||.||.:.:||:.||.|:||..
  Fly   974 LIIVSMLSVPS-IFYRPKGREDEADGVREKFQRPESDHLTYLNVYQQWRQNNYSSTWCNEHFIHI 1037

  Fly   759 RSMKRARDVREQLVGLMQRVEIDMVSCLPETVNVRKAATAGYFYHVARLSKGGHYKTIKHNQTVM 823
            ::|::.|:||:||..:|.:..:.::||..:...|||...:.|||..|||...|.|..::......
  Fly  1038 KAMRKVREVRQQLKDIMTQQNLSVISCGIDWDIVRKCICSAYFYQAARLKGIGEYVNLRTGMPCH 1102

  Fly   824 IHPNSSLF--EELPRWVLYHELVFTSKEYMRQVIEIESKWLLEVAPHYYKAKELEDSTNKKMPKV 886
            :||.|:|:  ...|.:|:||||:.|:||||:....::..||.|:.|.::..||...|..:|..:.
  Fly  1103 LHPTSALYGLGTTPDYVVYHELIMTAKEYMQCATAVDGYWLAELGPMFFSVKESGRSGREKKKQA 1167

  Fly   887 A 887
            |
  Fly  1168 A 1168

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
l(2)37Cb	NP_609946.1	HrpA	222..867	CDD:224557	322/705 (46%)
		DEXDc	269..408	CDD:238005	90/138 (65%)
		HELICc	491..581	CDD:197757	49/89 (55%)
		HA2	651..735	CDD:214852	42/83 (51%)
		OB_NTP_bind	770..869	CDD:285018	35/100 (35%)
l(1)G0007	NP_572947.1	DEXDc	529..715	CDD:214692	112/186 (60%)
		DEXDc	551..689	CDD:238005	90/138 (65%)
		HELICc	722..870	CDD:238034	72/148 (49%)
		HA2	932..1014	CDD:214852	42/82 (51%)
		OB_NTP_bind	1048..1148	CDD:285018	34/99 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45468113
Domainoid	1	1.000	98	1.000	Domainoid score	I366
eggNOG	1	0.900	-	-		E1_COG1643
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	234	1.000	Inparanoid score	I130
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D113216at33208
OrthoFinder	1	1.000	-	-		FOG0000059
OrthoInspector	1	1.000	-	-		otm51353
orthoMCL	1	0.900	-	-		OOG6_100085
Panther	1	1.100	-	-	P	PTHR18934
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X141
	11	10.800