Protein Alignment l(2)37Cb and Dhx16

DIOPT Version :10

• Sequence 1: NP_609946.1
• Gene: l(2)37Cb / 35192
• FlyBaseID: FBgn0086444
• Length: 894
• Species: Drosophila melanogaster
• Sequence 2: NP_997661.1
• Gene: Dhx16 / 294232
• RGDID: 1302963
• Length: 1044
• Species: Rattus norvegicus
• Alignment Length: 901
• Identity: 595/901 - (66%)
• Similarity: 739/901 - (82%)
• Gaps: 19/901 - (2%)

  Fly     2 SGKNRKRTASSSSSGEEPDSEEE------SRLKDLQERDEFASRLKKRDDDRTRNVVDSTGGRRA 60
            ||| ||...|.|.:.|:|.||:|      .||:||:|||.||.|:::||.||||||::.: .::|
  Rat   144 SGK-RKTGGSKSPTEEKPASEDEWERTERERLQDLEERDAFAERVRQRDKDRTRNVLERS-DKKA 206

  Fly    61 IEEATKRLKLEHEDRDKIVPHLRLQSRRQYLEKRKDDKVAELEADILDDEYLFDESVLTKREKEE 125
            .|||.||||:..|||..:||.||.:|||:||.||:.:|:.:|||::.|:|.||.:..|::.|:.|
  Rat   207 YEEAQKRLKMAEEDRKAMVPELRKKSRREYLAKREREKLEDLEAELADEEVLFGDVELSRHERRE 271

  Fly   126 REYKKQLLNIAKEHEKARELERIQ---RYNMPQDLKKGERSEYVEVDEFEK-QPNSEQKKWEAEQ 186
            .:||:::.::|:|:..|.|.|:::   ||:||:: .:|:.:...::.|.|. .|..||::||..:
  Rat   272 LKYKRRVRDLAREYRAAGEQEKLEATNRYHMPKE-TRGQPARATDIVEEESGAPGEEQRRWEEAR 335

  Fly   187 LASARFHFGAKDAKAEE-EYELLL--DDQIDFIQALTLDGSREKSSSRQPELTEKERKRLTLDET 248
            |.:|...|||:||.|:| :|:|:|  |:.|:|::|..|.|..|.||.  |.|:.:.:::.::...
  Rat   336 LDAASLKFGARDAAAQEPQYQLVLEEDETIEFVRAAQLQGDEEPSSG--PPLSAQAQQKESIQAV 398

  Fly   249 RRSLPVYPFKEDLIAAVKEHQVLIIEGETGSGKTTQVPQYLVEAGFTKDKKMIGCTQPRRVAAMS 313
            ||||||:||:|:|:.|:..|||||||||||||||||:||||.|.|:||....|.|||||||||||
  Rat   399 RRSLPVFPFREELLTAIANHQVLIIEGETGSGKTTQIPQYLFEEGYTKKGMKIACTQPRRVAAMS 463

  Fly   314 VAARVAEEMGVKLGNEVGYSIRFEDCTSDRTILKYMTDGTLHREFLSEPDLASYSVMIIDEAHER 378
            ||||||.|||||||||||||||||||||:||:|:|||||.|.||||||||||||||:::||||||
  Rat   464 VAARVAREMGVKLGNEVGYSIRFEDCTSERTVLRYMTDGMLLREFLSEPDLASYSVVMVDEAHER 528

  Fly   379 TLHTDILFGLVKDIARFRPELKLLISSATLDAEKFSAFFDDAPIFRIPGRRYPVDIFYTKAPEAD 443
            ||||||||||:||:||||||||:|::|||||..:|||||||||:|||||||:|||||||||||||
  Rat   529 TLHTDILFGLIKDVARFRPELKVLVASATLDTARFSAFFDDAPVFRIPGRRFPVDIFYTKAPEAD 593

  Fly   444 YIDACCVSVLQIHATQPLGDILVFLTGQDEIETCQEVLHDRVKRLGSKIRELIVIPVYANLPSDM 508
            |::||.|||||||.|||.||||||||||:|||...|:|.||.:|||||||||:|:|:||||||||
  Rat   594 YLEACVVSVLQIHVTQPPGDILVFLTGQEEIEAACEMLQDRCRRLGSKIRELLVLPIYANLPSDM 658

  Fly   509 QAKIFEPTPPNARKVILATNIAETSLTIDNIIYVIDPGFAKQNNFNSRTGMESLMVVPISKASAN 573
            ||:||:||||.||||::|||||||||||:.||||:||||.||.::|.|||||||.|.|.||||||
  Rat   659 QARIFQPTPPGARKVVVATNIAETSLTIEGIIYVLDPGFCKQKSYNPRTGMESLTVTPCSKASAN 723

  Fly   574 QRAGRAGRTAPGKCFRLYTAWAYKHELEDNTVPEIQRINLGNAVLMLKALGINDLIHFDFLDPPP 638
            ||||||||.|.||||||||||||:||||:.|||||||.:|||.||:||:|||:||:|||||||||
  Rat   724 QRAGRAGRVAAGKCFRLYTAWAYQHELEETTVPEIQRTSLGNVVLLLKSLGIHDLMHFDFLDPPP 788

  Fly   639 HETLVLALEQLYALGALNHHGELTKLGRRMAEFPVDPMMGKMLLASEKYKCSEEMVTIAAMLSVN 703
            :|||:||||||||||||||.||||..||:|||.|||||:.||:||||||.||||::|:|||||||
  Rat   789 YETLLLALEQLYALGALNHLGELTTSGRKMAELPVDPMLSKMILASEKYSCSEEILTVAAMLSVN 853

  Fly   704 SAIFYRPKDKIIHADTARKNFNHMHGDHLSLLQVYNQWAETDYSTQWCYENFIQYRSMKRARDVR 768
            ::||||||||::|||.||.||....||||.||.||.||||:.||:|||||||:|:|||:||||||
  Rat   854 NSIFYRPKDKVVHADNARVNFFLPGGDHLVLLNVYTQWAESGYSSQWCYENFVQFRSMRRARDVR 918

  Fly   769 EQLVGLMQRVEIDMVSCLPETVNVRKAATAGYFYHVARLSKGGHYKTIKHNQTVMIHPNSSLFEE 833
            |||.||::|||:.:.||..:.|.||||.|:|||||.|||::.| |:|:|..|||.|||||||||:
  Rat   919 EQLEGLLERVEVGLTSCQGDYVRVRKAITSGYFYHTARLTRSG-YRTVKQQQTVFIHPNSSLFEQ 982

  Fly   834 LPRWVLYHELVFTSKEYMRQVIEIESKWLLEVAPHYYKAKELEDSTNKKMPKVAGR 889
            .|||:||||||.|:||:||||:||||.|||||||||||||||||...|||||..|:
  Rat   983 QPRWLLYHELVLTTKEFMRQVLEIESSWLLEVAPHYYKAKELEDPHAKKMPKKVGK 1038

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
l(2)37Cb	NP_609946.1	PTZ00121	<6..267	CDD:173412	113/273 (41%)
		HrpA	251..>868	CDD:441249	471/616 (76%)
Dhx16	NP_997661.1	PTZ00121	<146..>410	CDD:173412	111/268 (41%)
		HrpA	401..>1028	CDD:441249	482/627 (77%)