Protein Alignment l(2)37Cb and prp43

DIOPT Version :10

• Sequence 1: NP_609946.1
• Gene: l(2)37Cb / 35192
• FlyBaseID: FBgn0086444
• Length: 894
• Species: Drosophila melanogaster
• Sequence 2: NP_595937.1
• Gene: prp43 / 2540057
• PomBaseID: SPBC16H5.10C
• Length: 735
• Species: Schizosaccharomyces pombe
• Alignment Length: 655
• Identity: 330/655 - (50%)
• Similarity: 457/655 - (69%)
• Gaps: 20/655 - (3%)

  Fly   247 ETRRSLPVYPFKEDLIAAVKEHQVLIIEGETGSGKTTQVPQYLVEAGFTK-DKKMIGCTQPRRVA 310
            ||||.||||..:|:.:....|:|:::..||||||||||:||:::...... ....|.||||||||
pombe    70 ETRRELPVYQQREEFLKIYHENQIIVFVGETGSGKTTQIPQFVLYDELPHLTNTQIACTQPRRVA 134

  Fly   311 AMSVAARVAEEMGVKLGNEVGYSIRFEDCTSDRTILKYMTDGTLHREFLSEPDLASYSVMIIDEA 375
            |||||.|||:||.|.||.||||:||||||:...|:|||||||.|.||.:::..|:.||.:|:|||
pombe   135 AMSVAKRVADEMDVDLGEEVGYNIRFEDCSGPNTLLKYMTDGMLLREAMTDHMLSRYSCIILDEA 199

  Fly   376 HERTLHTDILFGLVKDIARFRPELKLLISSATLDAEKFSAFFDDAPIFRIPGRRYPVDIFYTKAP 440
            |||||.||||.||:|.:|..||:||:::.||||||:||..:|.|||:..:|||.|||:|:||:.|
pombe   200 HERTLATDILMGLMKRLATRRPDLKIIVMSATLDAKKFQKYFFDAPLLAVPGRTYPVEIYYTQEP 264

  Fly   441 EADYIDACCVSVLQIHATQPLGDILVFLTGQDEIE-TCQEVL--HDRVKRLGSKIRELIVIPVYA 502
            |.||::|...:|||||..:..|||||||||::||| .|:::.  .|.:.|.|: ...|.|.|:|.
pombe   265 ERDYLEAALRTVLQIHVEEGPGDILVFLTGEEEIEDACRKITLEADDLVREGA-AGPLKVYPLYG 328

  Fly   503 NLPSDMQAKIFEPTPPN-----ARKVILATNIAETSLTIDNIIYVIDPGFAKQNNFNSRTGMESL 562
            :||.:.|.:||||||.:     .|||:::|||||||||||.|:||:||||:||..:|.|..:|||
pombe   329 SLPPNQQQRIFEPTPEDTKSGYGRKVVISTNIAETSLTIDGIVYVVDPGFSKQKIYNPRIRVESL 393

  Fly   563 MVVPISKASANQRAGRAGRTAPGKCFRLYTAWAYKHELEDNTVPEIQRINLGNAVLMLKALGIND 627
            :|.|||||||.|||||||||.|||||||||..|::.||.:.|.|||.|.||.:.||.||.|||:|
pombe   394 LVSPISKASAQQRAGRAGRTRPGKCFRLYTEEAFRKELIEQTYPEILRSNLSSTVLELKKLGIDD 458

  Fly   628 LIHFDFLDPPPHETLVLALEQLYALGALNHHGELTKLGRRMAEFPVDPMMGKMLLASEKYKCSEE 692
            |:|||::|||..||::.|||:|..|..|:.:|:||.|||:.:|||:||.:..||:.|.::.||.|
pombe   459 LVHFDYMDPPAPETMMRALEELNYLNCLDDNGDLTPLGRKASEFPLDPNLAVMLIRSPEFYCSNE 523

  Fly   693 MVTIAAMLSVNSAIFYRPKDKIIHADTARKNFNHMHGDHLSLLQVYNQWAETDYSTQWCYENFIQ 757
            ::::.|:|||.: :|.||......||..|:.|.|..||||:||.||:.:...:.:..||:.:|:.
pombe   524 VLSLTALLSVPN-VFVRPNSARKLADEMRQQFTHPDGDHLTLLNVYHAYKSGEGTADWCWNHFLS 587

  Fly   758 YRSMKRARDVREQLVGLMQRVEIDMVSCLPET----VNVRKAATAGYFYHVARLSKGG-HYKTIK 817
            :|::..|.:||:||...|:|.|::::|...:.    ||:|:|..:|:|..||:.|..| :|.|:|
pombe   588 HRALISADNVRKQLRRTMERQEVELISTPFDDKNYYVNIRRALVSGFFMQVAKKSANGKNYVTMK 652

  Fly   818 HNQTVMIHPNSSLFEELPRWVLYHELVFTSKEYMRQVIEIESKWLLEVAPHYYKAKELEDSTNKK 882
            .||.|.:||:..| ...|.||:|:|.|.|:|.::|.|..|..:||:|:||:||   :|:|..|.|
pombe   653 DNQVVSLHPSCGL-SVTPEWVVYNEFVLTTKSFIRNVTAIRPEWLIELAPNYY---DLDDFDNNK 713

  Fly   883 MPKVA 887
            ..|.|
pombe   714 EVKSA 718

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
l(2)37Cb	NP_609946.1	PTZ00121	<6..267	CDD:173412	9/19 (47%)
		HrpA	251..>868	CDD:441249	317/630 (50%)
prp43	NP_595937.1	HrpA	74..>701	CDD:441249	316/629 (50%)