Protein Alignment l(2)37Cb and ath

DIOPT Version :10

• Sequence 1: NP_609946.1
• Gene: l(2)37Cb / 35192
• FlyBaseID: FBgn0086444
• Length: 894
• Species: Drosophila melanogaster
• Sequence 2: XP_556838.4
• Gene: ath / 1276808
• VectorBaseID: AGAMI1_006394
• Length: 715
• Species: Anopheles gambiae
• Alignment Length: 676
• Identity: 284/676 - (42%)
• Similarity: 409/676 - (60%)
• Gaps: 24/676 - (3%)

  Fly   218 ALTLD-GSREKSSSRQPELTEKERKRLTLDETRRSLPVYPFKEDLIAAVKEHQVLIIEGETGSGK 281
            |:|:| |...::||...:.:....|:....:.|.|||:|..::.|:..|::...:|:.|||||||
Mosquito    40 AVTMDSGLSSRNSSLGNQYSRSYMKQEQAKQQRLSLPIYSVRKSLMEMVRKSSTIIVLGETGSGK 104

  Fly   282 TTQVPQYLVEAGFTKDKKMIGCTQPRRVAAMSVAARVAEEMGVKLGNEVGYSIRFEDCTSDRTIL 346
            |||:||::.|||...| |||..||||||||::||..||:|||..||:.|||::||||.||:.|.:
Mosquito   105 TTQMPQFIYEAGLNGD-KMIAITQPRRVAAITVAKWVAQEMGTNLGDLVGYTVRFEDMTSENTQV 168

  Fly   347 KYMTDGTLHREFLSEPDLASYSVMIIDEAHERTLHTDILFGLVKDIARFR-----PELKLLISSA 406
            ||||||.|.||.||:..|.:|:|:|:||.||||:.||:|.|:||...:.|     ..||::|.||
Mosquito   169 KYMTDGILCREALSDRQLRNYNVIILDEVHERTIATDVLLGVVKKAQQIRALKRMTPLKVIIMSA 233

  Fly   407 TLDAEKFSAFFDDAPIFRIPGRRYPVDIFYTKAPEADYIDACCVSVLQIHATQPLGDILVFLTGQ 471
            |:|.:.|:::|.|.||..:.||.|.|.: |....:..||:||..:|::||.|||.||:|||||||
Mosquito   234 TMDCDHFASYFSDCPIVYLQGRTYQVKV-YQMVEKMHYIEACLKTVVEIHQTQPAGDVLVFLTGQ 297

  Fly   472 DEIETCQEVLHDRVKRLGSKIRELIVIPVYANLPSDMQAKIFEPTPPNARKVILATNIAETSLTI 536
            :|||.....:....|.....:.:|.|.|:||.||.:.|..:|...|.|.||||.||||||||:||
Mosquito   298 EEIEATVGKMRRLAKSFSPDLPKLAVHPMYAALPQNQQLDVFNAAPGNVRKVIFATNIAETSITI 362

  Fly   537 DNIIYVIDPGFAKQNNFNSRTGMESLMVVPISKASANQRAGRAGRTAPGKCFRLYTAWAYKHELE 601
            :.|.||:|.|.||..:::..|||:.|.|..||:|.|:||.|||||.:.|.|:|.|:...|.| ||
Mosquito   363 NGIRYVVDCGRAKVRSYDPITGMDMLKVSWISQAQAHQRTGRAGRLSDGVCYRTYSKEVYGH-LE 426

  Fly   602 DNTVPEIQRINLGNAVLMLKALGINDLIHFDFLDPPPHETLVLALEQLYALGALN--HHGELTKL 664
            ..|:|||.|.|:...:|.|..:|:| ...|||:|.||.|.:|..|.:|.||.|::  .:..||.|
Mosquito   427 KMTMPEILRCNMAATILNLLVMGVN-YKDFDFIDKPPEEAIVGGLLELKALNAISSVENPILTAL 490

  Fly   665 GRRMAEFPVDPMMGKMLLASEKYKCSEEMVTIAAMLS----VNSAIFYRPKDKIIHADTARKNFN 725
            |.:||.||:||...||||::.|:.|.|||:||.||||    ..:::..|.:..|.|:     .|.
Mosquito   491 GTKMARFPLDPKYSKMLLSAPKFGCLEEMLTIIAMLSGENVFTNSVHKREQMLIAHS-----KFF 550

  Fly   726 HMHGDHLSLLQVYNQWAETDYSTQWCYENFIQYRSMKRARDVREQLVGLMQRVEIDMVSCLPETV 790
            ...|||::||.|:|::........||::||:..|::.....:||||..:.:.:::...:|..:|.
Mosquito   551 DRSGDHITLLNVFNEFKTRAKPKVWCFDNFLNERNLTHVASIREQLSEICKALDLPSSTCGKDTT 615

  Fly   791 NVRKAATAGYFYHVARLSKGGHYKTIKHNQTVMIHPNSSLFEEL-PRWVLYHELVFTSKEYMRQV 854
            .|.|....|.|.::|.......|.|........|||:|::..:. |..|:|.|||.|...|:|.|
Mosquito   616 PVAKCLLTGLFANIATKQPDHLYLTSTSALKARIHPSSAVCGKFRPPVVVYTELVATRLNYLRNV 680

  Fly   855 IEIESKWLLEVAPH--YYKAKELEDS 878
            .||:..|:.||.|:  .|:.|..:::
Mosquito   681 TEIDPAWIDEVVPNVSQYQTKGFKEN 706

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
l(2)37Cb	NP_609946.1	PTZ00121	<6..267	CDD:173412	14/49 (29%)
		HrpA	251..>868	CDD:441249	273/628 (43%)
ath	XP_556838.4	None