Protein Alignment l(2)37Cb and Dhx29

DIOPT Version :9

• Sequence 1: NP_609946.1
• Gene: l(2)37Cb / 35192
• FlyBaseID: FBgn0086444
• Length: 894
• Species: Drosophila melanogaster
• Sequence 2: XP_002729053.2
• Gene: Dhx29 / 100362324
• RGDID: 2318361
• Length: 1366
• Species: Rattus norvegicus
• Alignment Length: 1195
• Identity: 308/1195 - (25%)
• Similarity: 506/1195 - (42%)
• Gaps: 341/1195 - (28%)

  Fly    13 SSSGEEPDSEEESRLKDLQ-------------ERDEFASRLKKRDDDRTRNVVDSTGGRRAIEEA 64
            |...||...:...:.:.:|             :|.|...::|.:.::::..|.......|..|:.
  Rat   174 SQEFEEQQPKSRPKFQSVQIQATLSPPLQTKTKRQEEDPKIKPKKEEKSMEVNMKEWILRYAEQQ 238

  Fly    65 TKRLKLE----HEDRDKIVPHLR--------LQSRRQ----YLEKRK------DDKVAEL--EAD 105
            .:..|.|    .||.||..|:.|        |.::.|    .:||.|      .:|:.:.  |.:
  Rat   239 NEEEKSEGSKGSEDEDKFDPNQRYLNLAARLLDAKEQAAAFKVEKNKQGQKEAQEKIRKFQREME 303

  Fly   106 ILDDEYLFDESVLTKREKEEREYK------KQLLNI--------AKEHEKARELERIQ------- 149
            .|:|..:|:.::....::.||:..      :..||.        |.|.||.::.|...
  Rat   304 TLEDHPIFNPAIKISHQQNERKKAPLATDGESALNFNLFEKPAAATEEEKGKKKEPHDVRNFDYT 368

  Fly   150 -----------------RYNMPQD----------------------------------------- 156
                             |.|:|:.
  Rat   369 ARSWTGKSPKQFLIDWVRKNLPKSPNPSFEKVPVGRYWKCRVRVVKSEDDVLVVCPTILTEDGMQ 433

  Fly   157 ------------LKKGE----------RSEYVEVDEFEKQPNSEQKKWEA--------------- 184
                        |.||:          |..:||..:.||: ..|..|.|.
  Rat   434 AQHLGATLALYRLVKGQSVHQLLPPTYRDVWVEWSDEEKK-KEELNKMETNKPRDLFIAKLLSKL 497

  Fly   185 ---EQLASARFHFGAKDAKA---EEEYELLLDDQIDFIQALTLD--GSRE----KSSSRQPELTE 237
               :||...|.|...|...|   ||.:|.|:.|  :.:.||:|:  |:.:    ::..|:.:.|.
  Rat   498 KQQQQLQQQRQHPENKTETAEDPEESWENLVSD--EDLSALSLEPTGAEDLEPVRNLFRRLQSTP 560

  Fly   238 KERKRLTLDETRRSLPVYPFKEDLIAAVKEHQVLIIEGETGSGKTTQVPQYLVEAGFTKD----K 298
            |.::.|   :.|:.|||:..:..::..:|.|:|:::.|||||||:||||.:|:|.....|    |
  Rat   561 KYQRLL---KERQQLPVFKHRASIVETLKRHRVVVVAGETGSGKSTQVPHFLLEDLLLNDCGARK 622

  Fly   299 KMIGCTQPRRVAAMSVAARVAEEMGVKLG----NEV-GYSIRFEDCTSDRTILKYMTDGTLHREF 358
            ..|.||||||::|:|:|.||.||:|.:.|    |.: ||.||.|...|:.|.|.|.|.|.|.|:.
  Rat   623 CNIVCTQPRRISAVSLATRVCEELGCEGGPGGRNSLCGYQIRMESRASESTRLLYCTTGVLLRKL 687

  Fly   359 LSEPDLASYSVMIIDEAHERTLHTDILFGLVKDIARFRPELKLLISSATLDAEKFSAFFDDAPIF 423
            ..:..||..|.:|:||.|||::.:|.|..::|:|.:.|.:|.|::.|||:|::|||.:|...||.
  Rat   688 QEDGLLADVSHVIVDEVHERSVQSDFLLVILKEILQKRSDLHLILMSATVDSDKFSTYFTHCPIL 752

  Fly   424 RIPGRRYPVDIFYTK--APEADYI-----DAC--------------------------CVSVLQI 455
            ||.||.|||::|:.:  ..|..:|     :.|                          |:.| |.
  Rat   753 RISGRSYPVEVFHLEDIVEETGFILEKDSEYCQKFLEEEEEITINVTSKAGGIKKYQECIPV-QS 816

  Fly   456 HATQPL---------------------------------------------GDILVFLTGQDEIE 475
            .|:..|                                             |.:|:||.|...|:
  Rat   817 GASPELSPFYQKYSSRTQYAVLYMNPHKINLDLILELLVYLDKSPQFRNIEGAVLIFLPGLAHIQ 881

  Fly   476 TCQEVL-HDRVKRLGSKIRELIVIPVYANLPSDMQAKIFEPTPPNARKVILATNIAETSLTIDNI 539
            ...::| :||  |..|:..:||.:  ::.|.:..||..|...||..||::||||||||.:||.::
  Rat   882 QLYDLLSNDR--RFYSERYQLIAL--HSVLSTQDQAAAFMLPPPGVRKIVLATNIAETGITIPDV 942

  Fly   540 IYVIDPGFAKQNNFNSRTGMESLMVVPISKASANQRAGRAGRTAPGKCFRLYTAWAYKHELEDNT 604
            ::|||.|..|:|.::..:.|.||:...:|||||.||.|||||...|.||||||...::..|| .:
  Rat   943 VFVIDTGRTKENKYHESSQMSSLVETFVSKASALQRQGRAGRVRDGFCFRLYTRERFEGFLE-YS 1006

  Fly   605 VPEIQRINLGNAVL-MLKA-LGINDLIHFDF----LDPPPHETLVLALEQLYALGALN-HHGELT 662
            ||||.|:.|....| ::|. ||..:    ||    ||||..:.:..|:..|..:||.. ...:||
  Rat  1007 VPEILRVPLEELCLHIMKCDLGSPE----DFLSKALDPPQPQVISNAMNLLRKIGACEPSEPKLT 1067

  Fly   663 KLGRRMAEFPVDPMMGKMLLASEKYKCSEEMVTIAAMLSVNSAIFYRPKDKIIHADTARKNFNHM 727
            .||:.:|..||:..:||||:....:.|.|.:.|:||:::..|. |..|..:...||.|:.:....
  Rat  1068 PLGQHLAALPVNVKIGKMLIFGAIFGCLEPVATLAAVMTEKSP-FITPIGRKDEADLAKSSLAVA 1131

  Fly   728 HGDHLSLLQVYNQWAETDY------STQWCYENFIQYRSMKRARDVREQLVGLMQRVEIDMVSCL 786
            ..|||::...|..|.:...      ...:|..||:...|:....||:::|:.|::.......:..
  Rat  1132 DSDHLTIYNAYLGWKKAQQEGGFRSEISYCQRNFLNRTSLLTLEDVKQELMKLVRAAGFSSSTSW 1196

  Fly   787 -----PETVNVRKAA------TAGYFYHVARLSKGGHYKTIKHNQTV-----------MIHPNSS 829
                 |:.::.:..|      .||.:..|.::.   ..|::...:.:           .:|| ||
  Rat  1197 EGKKGPQALSFQDIALLKAVLAAGLYDSVGKIM---CTKSVDVTEKLACMVETAQGKAQVHP-SS 1257

  Fly   830 LFEELPR--WVLYHELVFTSKEYMRQV--------------IEIESK--------WL-----LEV 865
            :..:|..  |:||.|.|..::.|:|:.              ||::.:        |:     :::
  Rat  1258 VNRDLQTYGWLLYQEKVRYARVYLRETTLITPFPVLLFGGDIEVQHRERLLSVDGWIYFQAPVKI 1322

  Fly   866 APHYYKAKELEDSTNKKM---PKVA 887
            |..:.:.:.|.||..:|.   ||::
  Rat  1323 AVIFKQLRVLIDSVLRKKLENPKMS 1347

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
l(2)37Cb	NP_609946.1	HrpA	222..867	CDD:224557	236/802 (29%)
		DEXDc	269..408	CDD:238005	64/147 (44%)
		HELICc	491..581	CDD:197757	39/89 (44%)
		HA2	651..735	CDD:214852	27/84 (32%)
		OB_NTP_bind	770..869	CDD:285018	24/149 (16%)
Dhx29	XP_002729053.2	HrpA	531..1314	CDD:224557	238/800 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1643
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810