Protein Alignment l(2)37Cb and dhx29

DIOPT Version :10

• Sequence 1: NP_609946.1
• Gene: l(2)37Cb / 35192
• FlyBaseID: FBgn0086444
• Length: 894
• Species: Drosophila melanogaster
• Sequence 2: XP_004910409.1
• Gene: dhx29 / 100216168
• XenbaseID: XB-GENE-995260
• Length: 1363
• Species: Xenopus tropicalis
• Alignment Length: 1110
• Identity: 293/1110 - (26%)
• Similarity: 471/1110 - (42%)
• Gaps: 324/1110 - (29%)

  Fly    11 SSSSSGEEPDSEEESRLKDLQERDEFASRLKKRDDDRTRNVVDSTGGRRAIEEATKRLKLEHEDR 75
            :...|.::.:.|:|:.|:.....::|..  .:|..:.|..::|:    ||...|||      :|:
 Frog   229 AEQGSDDDEEEEKETALEKHPTSEKFDP--NERYLELTAKLLDA----RAQAAATK------QDK 281

  Fly    76 DKIVPHLRLQSRRQYLEKRKDDKVAELEADILDDEYLFDESVLTKREKEEREYKKQLLNIAKEHE 140
            ||       |.:::..|:.:.   .:.|...|:|..||:.:|.....|.|.:..:..|..:.|..
 Frog   282 DK-------QGQKEAQERIRG---YQQEMKSLEDHPLFNPAVKIPEVKSESKQPRPALPPSDEES 336

  Fly   141 KAREL-ERIQRYNMPQDLKK------------------GERSEYVEVD----EFEKQPNSEQKK- 181
            ....| |:|:  |.|:|..|                  |:..:...:|    .::|.||...:|
 Frog   337 LNFNLFEKIE--NAPEDKAKKKPPLDIRNFDYTSRSWTGKSPKQFLIDWCRKHYQKSPNPSFEKV 399

  Fly   182 -----WEA--------------------EQLASARFHFGAKDA-----KAEEEYELL-------- 208
                 |::                    |....|: |..|..|     |.:..::||
 Frog   400 PVGKYWKSRVKIIKSHDDVMCVCPTIVTEDSMQAQ-HLAATLALYELTKGQSVHQLLPPTYRDVW 463

  Fly   209 -----LDDQID-----------------FIQALTLDGSREKSSSRQP--ELTEKERKRLTLDE-- 247
                 .:.|:.                 .:..|.|..::.|||.:.|  |..|...:.|..||
 Frog   464 LEWSDAEKQVQEQNKMESNKPRDQFITKLLNKLKLQQNQLKSSGQNPVTEDPEDSWENLACDEEQ 528

  Fly   248 ----------------------------------TRRSLPVYPFKEDLIAAVKEHQVLIIEGETG 278
                                              .|..|||:..::.::..:|.|:|:::.||||
 Frog   529 IETCPSTAQTDDLEPIRNLLLKSRDSIKYKRLLNDREQLPVFAHRKFILETLKRHRVIVVAGETG 593

  Fly   279 SGKTTQVPQYLVE-----AGFTKDKKMIGCTQPRRVAAMSVAARVAEEMGVKLG----NEV-GYS 333
            |||:|||||:|:|     .| :..|..|.||||||::|||:|.||.||:|...|    |.: ||.
 Frog   594 SGKSTQVPQFLLEDLLLNRG-SPGKCNIVCTQPRRISAMSLATRVCEELGCDSGPGGRNSLCGYQ 657

  Fly   334 IRFEDCTSDRTILKYMTDGTLHREFLSEPDLASYSVMIIDEAHERTLHTDILFGLVKDIARFRPE 398
            ||.|..|.:.|.|.|.|.|.|.|:...:..|.:.|.:|:||.||||:.:|.|..::::|...|.:
 Frog   658 IRMESRTGEATRLLYCTTGILLRKLQEDSMLKNISHIIVDEVHERTVQSDFLLIILREILHKRSD 722

  Fly   399 LKLLISSATLDAEKFSAFFDDAPIFRIPGRRYPVDIFY--------------------------- 436
            |.|::.|||:|.||||::|...||.||.||.:||::|:
 Frog   723 LHLVLMSATVDCEKFSSYFTHCPIIRISGRTFPVEVFHLEDVVEATGFVLEQDSEYCQKFLEDEE 787

  Fly   437 -------------TKAPEADYIDACCVSVLQI------------HATQPL--------------- 461
                         ||..|  :|.|...:.|.:            ||...:
 Frog   788 EITLSVTGKGGSSTKYQE--FIPALSDTGLDLGQRYQRYSSQTRHAVLYMNPNKINLDLILELLV 850

  Fly   462 ------------GDILVFLTGQDEIETCQEVL------HDRVKRLGSKIRELIVIPVYANLPSDM 508
                        |.:|:||.|..:|:...::|      |||        |...:|.:::.|.|..
 Frog   851 FLDISPQYRNVEGAVLIFLPGLADIQQLYDILSSDKRFHDR--------RRYKLIALHSILSSQD 907

  Fly   509 QAKIFEPTPPNARKVILATNIAETSLTIDNIIYVIDPGFAKQNNFNSRTGMESLMVVPISKASAN 573
            ||:.|...|...||::||||||||.:||.::::|:|.|..|:|.::..:.|.||:...||||||.
 Frog   908 QAEAFILPPAGTRKIVLATNIAETGITIPDVVFVVDAGRTKENRYHESSQMSSLVETFISKASAL 972

  Fly   574 QRAGRAGRTAPGKCFRLYTAWAYKHELEDNTVPEIQRINLGNAVL-MLKA-LGINDLIHFDF--- 633
            ||.|||||...|.||||||...::..:| .:||||.|:.|....| ::|. ||..:    ||
 Frog   973 QRQGRAGRVRDGFCFRLYTRERFEGFME-YSVPEILRVPLEELCLHIMKCDLGSPE----DFLSK 1032

  Fly   634 -LDPPPHETLVLALEQLYALGALN-HHGELTKLGRRMAEFPVDPMMGKMLLASEKYKCSEEMVTI 696
             ||||..:.:..|:..|..:||.. ....||.||:.:|..||:..:||||:....:.|.:.:.|:
 Frog  1033 ALDPPQLQVISNAMNLLRKIGACELIQPRLTPLGQHLAALPVNVKIGKMLIFGAIFGCLDAVATL 1097

  Fly   697 AAMLSVNSAIFYRPKDKIIHADTARKNFNHMHGDHLSLLQVYNQW---------AETDYSTQWCY 752
            ||.::..|. |..|..:...||.|:.:....:.|||::.:.|..|         ||..|    |.
 Frog  1098 AATMTEKSP-FVTPIGEKDRADLAKSSMAVANSDHLTIFRAYLGWKAIRSDGYAAEMSY----CR 1157

  Fly   753 ENFIQYRSMKRARDVREQLVGLMQRVEID-------------MVSCLPETVNVRKA-ATAGYFYH 803
            :||:..:::....||:::|:.|::....:             |.:...|..::.|| .|||.:.:
 Frog  1158 KNFLNRKALLTIEDVKQELIRLVRAAGFECPRFVEPNGLSDNMKALSAEETSLLKAILTAGLYDN 1222

  Fly   804 VARL------------------SKGGHYKTIKHNQTVMIHPNSSLFEELPR--WVLYHELVFTSK 848
            |.::                  ::|          ...:|| ||:..:|..  |:||.|.:..||
 Frog  1223 VGKILFTNSVDITEKLACMVETAQG----------KAQVHP-SSVNRDLQTYGWLLYQEKIKYSK 1276

  Fly   849 EYMRQ 853
            .::|:
 Frog  1277 VFLRE 1281

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
l(2)37Cb	NP_609946.1	PTZ00121	<6..267	CDD:173412	66/377 (18%)
		HrpA	251..>868	CDD:441249	230/748 (31%)
dhx29	XP_004910409.1	HrpA	565..>1184	CDD:441249	209/639 (33%)
		OB_NTP_bind	1211..1297	CDD:400182	19/82 (23%)