Protein Alignment l(2)37Cb and sirt3.2

DIOPT Version :10

• Sequence 1: NP_609946.1
• Gene: l(2)37Cb / 35192
• FlyBaseID: FBgn0086444
• Length: 894
• Species: Drosophila melanogaster
• Sequence 2: NP_001120529.1
• Gene: sirt3.2 / 100145681
• XenbaseID: XB-GENE-5721494
• Length: 401
• Species: Xenopus tropicalis
• Alignment Length: 339
• Identity: 63/339 - (18%)
• Similarity: 114/339 - (33%)
• Gaps: 102/339 - (30%)

  Fly   284 QVPQYLVEAGFTKDKKMIGCTQPRRV-----------------AAMSVAARVAEEMGVKLG---N 328
            |:|:..:....:..|..|||.....:                 |.:|.|:.:.:......|   |
 Frog    92 QLPKSALAKNISAIKPNIGCNNLEDILDLITKNCCTNIIVMAGAGISTASGIPDFRTPGSGLYDN 156

  Fly   329 EVGYSIRFEDCTSDRTILKYMTDGT-----LHREFLS---EPDLASYSVMIIDEAHERTL----H 381
            ...|.|.:.:...|   :.|.....     |.:|...   :|:|..|.:.::   |::.|    :
 Frog   157 LQKYDIPYPEAIFD---INYFVCNPNPFFHLAKELFPGKYKPNLVHYFIKLL---HDKGLLLRCY 215

  Fly   382 TDILFGLVKDIARFRPELKLLISSATLDAEKF----SAFFDDAPIFRIPGRRYPVDIFYTKAP-- 440
            |..:.||.:              .|.:..||.    ..||..:           ..:.||..|
 Frog   216 TQNIDGLER--------------LAGIPVEKIVEVHGTFFSAS-----------CSLCYTPFPAN 255

  Fly   441 EA-----DYIDACCVSVLQIHATQPLGDILVFLTGQDEIETCQEVLHDRVKR-----LGSKIREL 495
            ||     |....||.     ....|:...:||. |:|..:|..:...|..|.     :|:.::
 Frog   256 EAKELIFDGNPPCCK-----FCAGPVKPDIVFF-GEDLPQTFTQAYQDFPKADLLIIMGTSLK-- 312

  Fly   496 IVIPVYANLPSDMQAKI------FEPTPPNARKVILATNIAETSLTIDNIIYVIDPGFAKQNNFN 554
              |..:|:|.:.::..|      .|...|.|:|.:...::||.....|.|..::       :..:
 Frog   313 --IEPFASLVNTVKPSIPRLLINREKVGPFAKKRLRRRDVAELGDLCDIIHTMV-------SRLS 368

  Fly   555 SRTGMESLMVVPIS 568
            .:..::.||..|.|
 Frog   369 WQAELDQLMNSPTS 382

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
l(2)37Cb	NP_609946.1	PTZ00121	<6..267	CDD:173412
		HrpA	251..>868	CDD:441249	63/339 (19%)
sirt3.2	NP_001120529.1	SIRT1	127..360	CDD:238699	52/273 (19%)