Protein Alignment l(2)37Cb and dhx37

DIOPT Version :9

• Sequence 1: NP_609946.1
• Gene: l(2)37Cb / 35192
• FlyBaseID: FBgn0086444
• Length: 894
• Species: Drosophila melanogaster
• Sequence 2: XP_005172500.1
• Gene: dhx37 / 100009635
• ZFINID: ZDB-GENE-030131-4505
• Length: 1153
• Species: Danio rerio
• Alignment Length: 1061
• Identity: 318/1061 - (29%)
• Similarity: 480/1061 - (45%)
• Gaps: 212/1061 - (19%)

  Fly     4 KNRKRTASSSSSGEEPDSEEESRLKD---LQERDEF------ASRLKKRDDDRTRNVVDSTGGRR 59
            |.|:::.|..::..:..:..:..::|   |:..|:.      |::.||:..:|     ..|..:.
Zfish    11 KGRQQSTSVQTAAADRQTNVQVEIQDGAVLKGVDDCNALVLPATKTKKQKVER-----PVTKKKA 70

  Fly    60 AIEEATKRLKLEHEDRDKIVPHLRLQSRRQYLEKRKDDKVAELEADIL---------DDEYLFDE 115
            ..::..|.|:...|.:||      ...|.:.|.|..:.::.|.|..:|         ...|...|
Zfish    71 LTKKQRKNLEKVLEQKDK------KAHRAEVLSKLAEVQLPEAELKLLYTTAKLGTGGKLYHIKE 129

  Fly   116 SVLTKREKEEREYKKQLLNIA--KEHEKARELERIQRYNMPQDLKKGERSEYVEVDEFEKQPNSE 178
            ||...::......|...|:.|  |...:|.|.|......|.:..:..:.||..:..|.||:..||
Zfish   130 SVNEGQDGGSSSVKISSLSGANRKRRREADEEEEENESEMSESSEDDDDSEESDSSEEEKEKISE 194

  Fly   179 QKKWEAEQLASA-RFHFGAKDAKAEEEYELLLDDQIDFIQALTLDGSREKSSSRQPELTEKERKR 242
            :|..|.:|.... :.....|:|..:||.:.....:.|...|:.:      ...|.||
Zfish   195 EKHTEEQQQQQVLKEETKPKEADMKEEKKAETWTKEDCKPAVFI------PVERLPE-------- 245

  Fly   243 LTLDETRRSLPVYPFKEDLIAAVKEHQVLIIEGETGSGKTTQVPQYLVEAGFTKDKKMIGCTQPR 307
              :.|.|..|||...::.::.|||:|:.:::.|||||||||||||:|.||||.....:||.|:||
Zfish   246 --IQEARLRLPVLAEEQIIMEAVKDHECVVLCGETGSGKTTQVPQFLYEAGFASSGGIIGVTEPR 308

  Fly   308 RVAAMSVAARVAEEMGVKLGNEVGYSIRFEDCTSDRTILKYMTDGTLHREFLSEPDLASYSVMII 372
            ||||:|::.|||.||.:..| .|.|.||:|...::.|.:|.||||.|.:|...:..|..|||:||
Zfish   309 RVAAISMSHRVATEMNLSSG-VVSYQIRYEGNVTENTKIKVMTDGVLLKEIQRDFLLQKYSVIII 372

  Fly   373 DEAHERTLHTDILFGLVKDIARFRPE----LKLLISSATLDAEKFS----AFFDDAPIFRIPGRR 429
            ||||||:::||||.||:..|...|.:    :||:|.||||..|.|:    .|....|:.::..|:
Zfish   373 DEAHERSVYTDILIGLLSRIVPLRNKKGLPMKLIIMSATLRVEDFTENKRLFSSPPPVIKVEARQ 437

  Fly   430 YPVDIFYTK-APEADYIDACCVSVLQIHATQPLGDILVFLTGQDEIET-CQ-------------- 478
            :.|.:.:.| .|..||.......:.:||...|.|.||||||||.|:.: |:
Zfish   438 FAVTVHFNKRTPMDDYTGETFRKICKIHRMLPPGGILVFLTGQAEVHSVCRRLRKAFPYKPNREH 502

  Fly   479 ----EVLHD-----RVKRL-------------------GSKIRE--------------------- 494
                |...|     |.|:.                   |.:.|:
Zfish   503 TDMMETEEDLKKSKRAKKKNVSLPRINLDNYSALPVDEGDEDRQAGIDEDDGEGSDLELELGDHP 567

  Fly   495 -------------LIVIPVYANLPSDMQAKIFEPTPPNARKVILATNIAETSLTIDNIIYVIDPG 546
                         |.|:|:|:.|..:.|||:|.|.|..:|..::|||:|||||||..|.||:|.|
Zfish   568 DTDHEEKADPSIPLYVLPLYSLLAPEQQAKVFRPPPAGSRLCVVATNVAETSLTIPGIKYVVDCG 632

  Fly   547 FAKQNNFNSRTGMESLMVVPISKASANQRAGRAGRTAPGKCFRLYTAWAYKHELEDNTVPEIQRI 611
            ..|:..::..||:.|..|..||:|||||||||||||.||.|:|||:: |...:....:..||.|.
Zfish   633 RVKKRFYDRVTGVSSFKVTWISQASANQRAGRAGRTEPGHCYRLYSS-AVFGDFSLFSEAEITRR 696

  Fly   612 NLGNAVLMLKALGINDLIHFDFLDPPPHETLVLALEQLYALGALN---HHGELTK---------- 663
            .:.:.||.:|.|.|..:::|.|..||..|.|:.|.|.|.:||||.   .||.|::
Zfish   697 PVEDLVLQMKDLNIEKVVNFPFPTPPSSEALIAAEELLISLGALEKPARHGRLSEMEKARLSCPI 761

  Fly   664 --LGRRMAEFPVDPMMGKMLLASEKYKCSEEMVTIAAMLSVNSAI--FYRPKDKIIHADTARKNF 724
              |||.||.|||.|...|||....:..|.:.::||.:.::|....  :.||      |.:..:|.
Zfish   762 SPLGRAMAAFPVAPRYAKMLALGRQQGCMQYIITIVSAMTVREIFEDYDRP------AGSEEENV 820

  Fly   725 NHMHGDHLSLLQVYNQWAETDYS----------------------TQWCYENFIQYRSMKRARDV 767
            . |.|.....:|:...||....|                      .|:|.||.:::::|...|.:
Zfish   821 K-MSGKKARSVQMRRLWAGQGASLLLGDLMVLLGAVGACEFAGLTPQFCEENGLRFKAMLEIRRL 884

  Fly   768 REQLVGLMQRVEID---------------MVSCLPETVNVRKAATAGYFYHVARLSKG------- 810
            |.||...:..|..|               .|.||      |:...||...|:||..:.
Zfish   885 RGQLTNAVNAVCADADVYVDNKMAPPTEAQVLCL------RQIVLAGLGDHIARRVQAEELLDPK 943

  Fly   811 --GHYKTIKHNQTVMIHPNSSLFEELPRWVLYHELVFTSKEYMRQVIEIESKWLLEVAPHYYKAK 873
              ..|||...:..|.|||:|:|.:.||.:|:|.|::.|:|.|||.|..::..|:.::.|.|....
Zfish   944 WRNAYKTPLLDDPVFIHPSSALHKTLPEFVVYQEIMETTKMYMRGVCAVQDDWIPKLLPQYCHFS 1008

  Fly   874 ELEDSTNKKMPKVAGRAEMAQ 894
            ..|:|...:...:.||.:..|
Zfish  1009 APEESPAPRFCPLIGRVKCHQ 1029

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
l(2)37Cb	NP_609946.1	HrpA	222..867	CDD:224557	261/793 (33%)
		DEXDc	269..408	CDD:238005	72/142 (51%)
		HELICc	491..581	CDD:197757	45/123 (37%)
		HA2	651..735	CDD:214852	29/100 (29%)
		OB_NTP_bind	770..869	CDD:285018	35/122 (29%)
dhx37	XP_005172500.1	HrpA	200..1007	CDD:224557	270/837 (32%)
		DEXDc	272..412	CDD:238005	72/140 (51%)
		HELICc	583..667	CDD:197757	43/83 (52%)
		HA2	730..781	CDD:282288	20/50 (40%)
		HA2	761..>813	CDD:214852	18/57 (32%)
		OB_NTP_bind	<918..1004	CDD:285018	29/91 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1643
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D354219at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.820