Protein Alignment Ddc and SGPL1

DIOPT Version :10

• Sequence 1: NP_724163.1
• Gene: Ddc / 35190
• FlyBaseID: FBgn0000422
• Length: 510
• Species: Drosophila melanogaster
• Sequence 2: NP_001425282.1
• Gene: SGPL1 / 8879
• HGNCID: 10817
• Length: 579
• Species: Homo sapiens
• Alignment Length: 250
• Identity: 51/250 - (20%)
• Similarity: 90/250 - (36%)
• Gaps: 70/250 - (28%)

  Fly   162 ELPAEF--LACSGGKGG----GVIQGTASESTLVALLG----AKAKKLKEVKELHPEWDEHTILG 216
            ::.||.  :|||...||    |.:....:||.|:|...    |..|.:|..:.:.|:
Human   194 KIEAEIVRIACSLFNGGPDSCGCVTSGGTESILMACKAYRDLAFEKGIKTPEIVAPQ-------- 250

  Fly   217 KLVGYCSDQAHSSVERAGLLGGVKL-RSVQSENHRMRGAALEKAIEQDVA----------EGLIP 270
                    .||::..:|....|:|: |...::...:...|:.:||.::.|          .|:|
Human   251 --------SAHAAFNKAASYFGMKIVRVPLTKMMEVDVRAMRRAISRNTAMLVCSTPQFPHGVI- 306

  Fly   271 FYAVVTLGTTNSCAFDYLDECGPVGNKHNLWIHVDAAYAGSAFICPE---------YRHLMKGIE 326
                           |.:.|...:..|:.:.:||||...|...:..|         :...:||:.
Human   307 ---------------DPVPEVAKLAVKYKIPLHVDACLGGFLIVFMEKAGYPLEHPFDFRVKGVT 356

  Fly   327 SADSFNFNPHKWMLVNFDCSAMWLKDPSWVVNAFNVDP-----LYLKHDMQGSAP 376
            |..:   :.||:.......|.:...|..:....|.||.     :|....:.||.|
Human   357 SISA---DTHKYGYAPKGSSLVLYSDKKYRNYQFFVDTDWQGGIYASPTIAGSRP 408

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ddc	NP_724163.1	Pyridoxal_deC	70..446	CDD:395219	50/249 (20%)
SGPL1	NP_001425282.1	None