Protein Alignment Ddc and SGPL1

DIOPT Version :9

• Sequence 1: NP_724163.1
• Gene: Ddc / 35190
• FlyBaseID: FBgn0000422
• Length: 510
• Species: Drosophila melanogaster
• Sequence 2: NP_003892.2
• Gene: SGPL1 / 8879
• HGNCID: 10817
• Length: 568
• Species: Homo sapiens
• Alignment Length: 250
• Identity: 51/250 - (20%)
• Similarity: 90/250 - (36%)
• Gaps: 70/250 - (28%)

  Fly   162 ELPAEF--LACSGGKGG----GVIQGTASESTLVALLG----AKAKKLKEVKELHPEWDEHTILG 216
            ::.||.  :|||...||    |.:....:||.|:|...    |..|.:|..:.:.|:
Human   183 KIEAEIVRIACSLFNGGPDSCGCVTSGGTESILMACKAYRDLAFEKGIKTPEIVAPQ-------- 239

  Fly   217 KLVGYCSDQAHSSVERAGLLGGVKL-RSVQSENHRMRGAALEKAIEQDVA----------EGLIP 270
                    .||::..:|....|:|: |...::...:...|:.:||.::.|          .|:|
Human   240 --------SAHAAFNKAASYFGMKIVRVPLTKMMEVDVRAMRRAISRNTAMLVCSTPQFPHGVI- 295

  Fly   271 FYAVVTLGTTNSCAFDYLDECGPVGNKHNLWIHVDAAYAGSAFICPE---------YRHLMKGIE 326
                           |.:.|...:..|:.:.:||||...|...:..|         :...:||:.
Human   296 ---------------DPVPEVAKLAVKYKIPLHVDACLGGFLIVFMEKAGYPLEHPFDFRVKGVT 345

  Fly   327 SADSFNFNPHKWMLVNFDCSAMWLKDPSWVVNAFNVDP-----LYLKHDMQGSAP 376
            |..:   :.||:.......|.:...|..:....|.||.     :|....:.||.|
Human   346 SISA---DTHKYGYAPKGSSLVLYSDKKYRNYQFFVDTDWQGGIYASPTIAGSRP 397

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ddc	NP_724163.1	Pyridoxal_deC	70..446	CDD:278699	50/249 (20%)
SGPL1	NP_003892.2	DOPA_deC_like	144..507	CDD:99743	50/249 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0076
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810